Results 101 to 110 of about 5,405,992 (262)

of Postnatal developmental dynamics of cell type specification genes in Brn3a/Pou4f1 Retinal Ganglion Cells

open access: yes, 2018
of Postnatal developmental dynamics of cell type specification genes in Brn3a/Pou4f1 Retinal Ganglion ...
Vladimir Muzyka (5471207)   +2 more
core   +1 more source

AKAP1 Protects Retinal Ganglion Cells and Preserves Vision by Improving Mitochondrial and Synaptic Health in Glaucomatous Neurodegeneration

open access: yesAdvanced Science, EarlyView.
Intravitreal AAV2‐mediated AKAP1 restoration enhances mitochondrial fusion and biogenesis, improves bioenergetic capacity, and preserves mitochondrial integrity in glaucomatous RGCs. AKAP1 stabilizes presynaptic structure, maintaining synaptic protein expression, and limiting complement‐associated neuroinflammation.
Tonking Bastola   +10 more
wiley   +1 more source

A Novel Constitutional TUBB Variant Associated With Familial Malformations of Cortical Development

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Most pathogenic tubulin variants arise de novo in sporadic patients, causing severe brain malformations and significant neurodevelopmental impairment. The resulting reproductive disadvantage typically prevents these mutations from being transmitted to offspring.
Elena Cellini   +9 more
wiley   +1 more source

Ocular morphology and morphometry of the great egret (Ardea alba): A comprehensive anatomical description

open access: yesThe Anatomical Record, EarlyView.
Abstract Ardea alba (Linnaeus, 1758) is widely distributed, yet knowledge of its ocular morphology remains limited. This study described the morphometry and morphology of the eyeball and its accessory glands in six specimens using radiography, morphometry, light and scanning electron microscopy, and 3D scanning.
Julia Vaz Feio   +6 more
wiley   +1 more source

Intrinsically photosensitive (melanopsin) retinal ganglion cell function in glaucoma

open access: yes, 2011
Purpose. To determine whether glaucoma alters intrinsically photosensitive retinal ganglion cell (ipRGC) function. Methods. Forty-one patients (25 with glaucoma and 16 healthy age-matched control participants) were tested.
Thomas, Ravi   +7 more
core   +1 more source

Distribution of doublecortin in the developing retina of birds: A comparative analysis

open access: yesThe Anatomical Record, EarlyView.
Abstract The avian retina presents an elegant and highly accessible model for investigating the spatial and temporal dynamics of neurogenesis within the central nervous system. In recent years, the microtubule cytoskeleton has emerged not merely as a structural scaffold, but as a dynamic regulator of the transition of a morphologically homogeneous pool
Javier Francisco‐Morcillo   +5 more
wiley   +1 more source

A Novel In Vitro Sensing Configuration for Retinal Physiology Analysis of a Sub-Retinal Prosthesis

open access: yesSensors, 2012
This paper presents a novel sensing configuration for retinal physiology analysis, using two microelectrode arrays (MEAs). In order to investigate an optimized stimulation protocol for a sub-retinal prosthesis, retinal photoreceptor cells are stimulated,
Kyung Hwan Kim   +6 more
doaj   +1 more source

Retinal ganglion cell-specific genetic regulation in primary open-angle glaucoma

open access: yes, 2022
Retinal ganglion cell-specific genetic regulation in primary open-angle ...
P Sivakumaran (9885827)   +26 more
core  

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

open access: yesBMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma   +8 more
wiley   +1 more source

Neuroprotective effects of VCP modulators in mouse models of glaucoma

open access: yesHeliyon, 2016
Glaucoma is a major cause of adult blindness due to gradual death of retinal ganglion cells. Currently, no therapeutics are available for the protection of these cells from the cell death. We have recently succeeded in synthesizing novel compounds, KUSs (
Noriko Nakano   +10 more
doaj   +1 more source

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