Results 101 to 110 of about 72,734 (313)
Stem Cells, Retinal Ganglion Cells and Glaucoma [PDF]
, 2014 Retinal ganglion cells (RGCs) represent an essential neuronal cell type for vision. These cells receive inputs from light-sensing photoreceptors via retinal interneurons and then relay these signals to the brain for further processing. RGC diseases that result in cell death, e.g.
Valentin M, Sluch, Donald J, Zack
openaire +2 more sources
Zebrafish inversin mutants develop scoliosis in the absence of laterality defects
Developmental Dynamics, EarlyView.Abstract Background Human mutations in INVERSIN are associated with nephronophthisis, variable penetrance of situs inversus and congenital heart disease. Inversin has been shown to localize to cilia and many of the patient phenotypes are attributed to disrupted cilia function.
Christopher J. Derrick +3 more
wiley +1 more source
Hypoxia-ischemia and retinal ganglion cell damage
, 2008 Charanjit Kaur1, Wallace S Foulds2, Eng-Ang Ling11Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; 2Singapore Eye Research Institute, SingaporeAbstract: Retinal hypoxia is the potentially blinding ...
Eng-Ang Ling +2 more
core
Neuroprotective effects of VCP modulators in mouse models of glaucoma
Heliyon, 2016 Glaucoma is a major cause of adult blindness due to gradual death of retinal ganglion cells. Currently, no therapeutics are available for the protection of these cells from the cell death. We have recently succeeded in synthesizing novel compounds, KUSs (
Noriko Nakano +10 more
doaj +1 more source
Inherited metabolic epilepsies–established diseases, new approaches
Epilepsia Open, EarlyView.Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source
Retinal Ganglion Cell Loss in Diabetes Associated with Elevated Homocysteine
, 2009 A number of studies have suggested that homocysteine may be a contributing factor to development of retinopathy in diabetic patients based on observed correlations between elevated homocysteine levels and the presence of retinopathy.
Kenneth S. Shindler
core
Frontiers in Neuroscience, 2015 Knowledge of neuronal cell types in the mammalian retina is important for the understanding of human retinal disease and the advancement of sight-restoring technology, such as retinal prosthetic devices.
Ian L Jones +7 more
doaj +1 more source
InfoMat, EarlyView.We developed a bio‐inspired artificial retina in which curved artificial receptive fields composed of perovskite photoconductors perform multiply‐and‐accumulate operations through in‐sensor computing. This architecture simultaneously realized the structural efficiency of human eyes (compact single‐lens imaging system) and functional advantages of ...
Jisang Ha +8 more
wiley +1 more source
GABA_{B} Receptors Regulate Chick Retinal Calcium Waves
, 2001 Correlated spiking activity and associated Ca²⁺ waves in the developing retina are important in determining the connectivity of the visual system. Here, we show that GABA, via GABA_{B} receptors, regulates the temporal characteristics of Ca²⁺ waves ...
Catsicas, M, Mobbs, P
core
Retinal ganglion cell/inner plexiform layer thickness in patients with Parkinson’s disease
, 2017 Introduction: The aim of the paper was to analyze the changes in the macular ganglion cell layer and inner plexiform layer (GCL-IPL) thickness in patients with Parkinson’s disease.
Marko Zlatanović +9 more
core +1 more source