Results 111 to 120 of about 72,734 (313)

Effects of High Salt-Exposure on the Development of Retina and Lens in 5.5-Day Chick Embryo [PDF]

, 2014
Background/Aims: Excess maternal salt intake during pregnancy may alter fetal development. However, our knowledge on how an increased salt intake during pregnancy influences fetal eye development is limited.
Xiao-yu Wang, Manli Chuai, Guang Wang, Ma, Zheng-lai, Hocher, Berthold (Prof.), Karoline von Websky, Xuesong Yang, Chen, Yao, Wang, Guang, von Websky, Karoline, Yang, Xuesong, You-peng Chen, Chuai, Manli, Hocher, Berthold, Yao Chen, Berthold Hocher, Chen, You-peng, Wang, Xiao-yu, Zheng-lai Ma   +18 more
core   +1 more source

Modulation of the expression of the transcription factor Max in rat retinal ganglion cells by a recombinant adeno-associated viral vector

Brazilian Journal of Medical and Biological Research, 2005
Exclusion of the transcription factor Max from the nucleus of retinal ganglion cells is an early, caspase-independent event of programmed cell death following damage to the optic axons.
H. Petrs-Silva, V. Chiodo, L.B. Chiarini, W.W. Hauswirth, R. Linden   +4 more
doaj   +1 more source

Ex Vivo Evaluation of Poly(Solketal Acrylate) Nanoparticles for Intravitreal Drug Delivery to the Posterior Eye Segment

Macromolecular Rapid Communications, EarlyView.
Nile Red‐loaded poly(solketal acrylate) nanoparticles enable fluorescence tracking and exhibit nontoxic profiles in retinal cells. Enhanced cellular uptake and deep retinal penetration after intravitreal injection highlight their excellent potential for targeted ocular drug delivery to the posterior segment of the eye.
Yasaman Pourdakheli Hamedani, José Hurst, Malte Ritter, Philipp Weingarten, Julia Skokowa, Sven Schnichels, Friederike Adams   +6 more
wiley   +1 more source

Homogenous Cell Transplantation Trials in Parkinson's Disease: A Systematic Review and Meta‐Analysis

Movement Disorders Clinical Practice, EarlyView.
Abstract Background The transplantation of homogenous cells has emerged as an investigational strategy for Parkinson's disease (PD), offering an alternative to symptomatic treatment. Objective We performed a systematic review and meta‐analysis to assess its clinical efficacy and safety.
Nolan Reinisch, Athena Mancini, Adham Elsherbini, Jason Yuen, Andres Lozano   +4 more
wiley   +1 more source

Functional and cell-specific regulation of the Brn-3b transcription factor by microRNAs

, 2010
Post-transcriptional gene regulation is a very powerful and evolutionary conserved mechanism which allows cells to finely modulate gene expression by acting at the level of their mRNAs.
Calissano, M.
core  

Vision recovery despite retinal ganglion cell loss in Leber’s hereditary optic neuropathy

, 2016
PURPOSE\ud \ud - To report vision recovery in a single case of Leber's hereditary optic neuropathy (LHON) (mtDNA14484/ND6 mutation) with longitudinal documentation of retinal ganglion cell layer by ocular coherence tomography (OCT) that includes the pre-
Ann L. Webber, Webber, Ann L.
core   +1 more source

Trainable COSFIRE filters for vessel delineation with application to retinal images [PDF]

, 2015
Retinal imaging provides a non-invasive opportunity for the diagnosis of several medical pathologies. The automatic segmentation of the vessel tree is an important pre-processing step which facilitates subsequent automatic processes that contribute to ...
Petkov, Nicolai, Azzopardi, George
core   +1 more source

Melanopsin‐Mediated Post‐Illumination Pupillary Response in Idiopathic Rapid Eye Movement (REM) Sleep Behavior Disorder and Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Aims To conduct a case–control study to investigate melanopsin‐mediated post‐illumination pupillary response (PIPR) in patients with Parkinson's disease (PD), video‐polysomnography‐confirmed isolated/idiopathic rapid eye movement (REM) sleep behavior disorder (iRBD), and age‐matched healthy controls (HC). Methods PIPR was measured at 6 s after
Joey W.Y. Chan, Bei Huang, Siyi Gong, Yuhua Yang, Shi Tang, Steven Wai‐ho Chau, Ngan Yin Chan, Tim Man‐ho Li, Yaping Liu, Anne Y.Y. Chan, Karen K.Y. Ma, Shirley X. Li, Joshua Tsoh, Kelvin K.L. Chong, Kathryn A. Roecklein, Vincent C.T. Mok, Yun Kwok Wing   +16 more
wiley   +1 more source

Distribution of melanopsin positive neurons in pigmented and albino mice: evidence for melanopsin interneurons in the mouse retina.

, 2014
Here we have studied the population of intrinsically photosensitive retinal ganglion cells (ipRGCs) in adult pigmented and albino mice. Our data show that although pigmented (C57Bl/6) and albino (Swiss) mice have a similar total number of ipRGCs, their ...
Ortín-Martínez, A, Vidal-Sanz, M, Agudo-Barriuso, M, Valiente-Soriano, FJ, García-Ayuso, D, Galindo-Romero, C, Vugler, AA, Jiménez-López, M, Villegas-Pérez, MP   +8 more
core  

Retinal ganglion cell vulnerability to pathogenic tau in Alzheimer's disease. [PDF]

Acta Neuropathol Commun
Pathological tau isoforms, including hyperphosphorylated tau at serine 396 (pS396-tau) and tau oligomers (Oligo-tau), are elevated in the retinas of patients with mild cognitive impairment (MCI) due to Alzheimer’s disease (AD) and AD dementia.
Davis MR, Robinson E, Koronyo Y, Salobrar-Garcia E, Rentsendorj A, Gaire BP, Mirzaei N, Kayed R, Sadun AA, Ljubimov AV, Schneider LS, Hawes D, Black KL, Fuchs DT, Koronyo-Hamaoui M.   +14 more
europepmc   +2 more sources