Knowledge of neuronal cell types in the mammalian retina is important for the understanding of human retinal disease and the advancement of sight-restoring technology, such as retinal prosthetic devices.
Ian L Jones+7 more
doaj +1 more source
Activated retinal glia mediated axon regeneration in experimental glaucoma
Glaucoma, a leading cause of blindness, is a neurodegenerative disease characterized by progressive loss of retinal ganglion cell axons in the optic nerve and their cell bodies in the retina.
Barbara Lorber+3 more
doaj
Clinically Verified Hybrid Deep Learning System for Retinal Ganglion Cells Aware Grading of Glaucomatous Progression [PDF]
Objective: Glaucoma is the second leading cause of blindness worldwide. Glaucomatous progression can be easily monitored by analyzing the degeneration of retinal ganglion cells (RGCs). Many researchers have screened glaucoma by measuring cup-to-disc ratios from fundus and optical coherence tomography scans. However, this paper presents a novel strategy
arxiv
Revealing structure components of the retina by deep learning networks [PDF]
Deep convolutional neural networks (CNNs) have demonstrated impressive performance on visual object classification tasks. In addition, it is a useful model for predication of neuronal responses recorded in visual system. However, there is still no clear understanding of what CNNs learn in terms of visual neuronal circuits. Visualizing CNN's features to
arxiv
Functional imaging of ganglion and receptor cells in living human retina by osmotic contrast [PDF]
Imaging neuronal activity non-invasively in vivo is of tremendous interest, but current imaging techniques lack either functional contrast or necessary microscopic resolution. The retina is the only part of the central nervous system (CNS) that allows us direct optical access.
arxiv
Editorial: Molecular dynamics of cognitive-motor impairment in neurodegenerative diseases
Dhiraj Kumar+5 more
doaj +1 more source
Neuronal Nitric Oxide Synthase Is Crucial for Ganglion Cell Death in Rat Retinal Explant Cultures
We examined possible involvement of nitric oxide synthase (NOS) on ganglion cell death in explant cultures of neonatal rat retina. Survival of retinal ganglion cells was significantly prolonged by a broad-spectrum NOS inhibitor Nω-nitro-L-arginine ...
Hiroshi Katsuki+4 more
doaj
NUTRITION AND VASCULAR SUPPLY OF RETINAL GANGLION CELLS DURING HUMAN DEVELOPMENT
Purpose. To review the roles of the different vascular beds nourishing the inner retina (retinal ganglion cells) during normal development of the human eye and using our own tissue specimens to support our conclusions.Methods.
Paul eRutkowski, Christian-Albrecht eMay
doaj +1 more source
How does the inner retinal network shape the ganglion cells receptive field : a computational study [PDF]
We consider a model of basic inner retinal connectivity where bipolar and amacrine cells interconnect, and both cell types project onto ganglion cells, modulating their response output to the brain visual areas. We derive an analytical formula for the spatio-temporal response of retinal ganglion cells to stimuli taking into account the effects of ...
arxiv
Neural System Identification with Spike-triggered Non-negative Matrix Factorization [PDF]
Neuronal circuits formed in the brain are complex with intricate connection patterns. Such complexity is also observed in the retina as a relatively simple neuronal circuit. A retinal ganglion cell receives excitatory inputs from neurons in previous layers as driving forces to fire spikes.
arxiv