Results 241 to 250 of about 4,628,424 (310)

OPTN protects retinal ganglion cells and ameliorates neuroinflammation in optic neuropathies. [PDF]

Commun Biol
Wang Q, Wang Y, Jiang YDD, Donahue R, Cao G, Yan W, Guo H, Li Z, Liang J, Hao J, Lu Y, Bei F, Wang Q, Tian F.   +13 more
europepmc   +1 more source

Müller Glia–Vasculature Interactions in the Developing Retina

Glia, Volume 74, Issue 10, October 2026.
Retinal vascular layers form normally despite loss of cholinergic retinal waves. Müller glial processes contact endothelial tip cells early and form Aquaporin‐4‐enriched endfeet. Glial endfoot calcium signals are compartmentalized and occur largely independently of neural activity. ABSTRACT Coordinated signaling among neurons, glia, and the vasculature
Samira Monshietehadi, Angel J. Garcia, Benjamin E. Smith, Matthew Tarchick, Kiara Abhayaratne, Aileen Conley, Marla B. Feller   +6 more
wiley   +1 more source

Photodisruption of the Inner Limiting Membrane Promotes Retinal Engraftment of Stem-Cell Derived Retinal Ganglion Cells. [PDF]

Invest Ophthalmol Vis Sci
De Coster E, De Clerck K, De Clercq C, Li W, Punj D, Vanmeerhaeghe B, Verdonck J, De Smedt S, Braeckmans K, Hadady H, Remaut K, Johnson TV, Peynshaert K.   +12 more
europepmc   +1 more source

Mesenchymal Stem Cell‐Derived Extracellular Vesicles Ameliorate NaIO3‐Induced Dry AMD by Delivering miR‐486‐3p to Inhibit Lipocalin‐2‐Mediated Ferroptosis

MedComm, Volume 7, Issue 10, October 2026.
Our study reveals a novel mechanism by which MSC‐derived EVs alleviate NaIO3‐induced dry AMD‐like pathology. MSC‐EVs deliver miR‐486‐3p into retinal cells to directly inhibit the ferroptosis‐promoting target gene Lcn2. Concurrently, downregulated Lcn2 restores intracellular Gpx4 expression, thereby suppressing ferroptosis and rescuing retinal ...
Zheng Li, Tujing Zhao, Lin Ye, Runze Li, Huaping Tian, Ruilin Liao, Lulin Huang   +6 more
wiley   +1 more source

Epothilone B stabilizes microtubules via Tau to protect retinal ganglion cells and promote axon regeneration. [PDF]

Cell Commun Signal
Liang Y, Chi J, Sun YJ, Li YZ, Li YL, Li GY.   +5 more
europepmc   +1 more source

In Situ Hybridization and RT‐PCR Detection of Nervous Necrosis Virus in Fourfinger Threadfin, Eleutheronema tetradactylum, in Taiwan

Journal of Fish Diseases, Volume 49, Issue 10, October 2026.
ABSTRACT Between April and July 2020, suspected outbreaks of nervous necrosis virus (NNV) infection were observed in fourfinger threadfin (Eleutheronema tetradactylum) fingerling hatcheries in Pingtung County, southern Taiwan. Affected fish exhibited spiral swimming behaviour and abdominal distension, resulting in mortality rates between 50% and 100 ...
Chia‐Yu Hsieh, Shang‐Ting Wu, Chun‐Ying Lin   +2 more
wiley   +1 more source

Overexpression or Activation of Potassium Channel TASK-3 Protects Retinal Ganglion Cells and Restores Visual Function in Optic Nerve Crush. [PDF]

Invest Ophthalmol Vis Sci
Zhang J, Chen X, Ji J, Chen P, Yao J, Jiang R, Liu L, Wen X.   +7 more
europepmc   +1 more source

Nucleic Acids as Emerging Regulators of Calcium Phosphate Biomineralization

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
Calcium phosphate biomineralization has traditionally been considered a protein‐regulated process. This review highlights the emerging role of nucleic acids, which interact with mineral phases through adsorption, coprecipitation, and templating, thereby influencing crystal nucleation and growth.
Fanny Duhalde, Jessem Landoulsi, Xavier Houard   +2 more
wiley   +1 more source

Effects of a ROCK Inhibitor on Retinal Ganglion Cells In Vivo and In Vitro. [PDF]

J Clin Med
Chen W, Iizuka Y, Mabuchi F, Kashiwagi K.   +3 more
europepmc   +1 more source

PEBP1 Regulates Ferroptosis in Acute Glaucoma: Targeted Therapy Using Engineered Exosomes

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
General schematic diagram of Spatial and Single‐Cell Transcriptomics Identifies PEBP1 as a Ferroptosis Mediator in Glaucoma: Targeted Intervention by Engineered Stem Cell Exosomes. ABSTRACT Glaucoma is the leading cause of irreversible blindness worldwide, primarily driven by the progressive loss of retinal ganglion cells (RGCs) under pathological high
Yijia Huang, Di Gong, Junhong Guo, Wei Huang, Tingyu Hu, Shengbin Tang, Li Li, Bingkai Feng, Kuanrong Dang, Simin Deng, Yong Liu, Chunyan Tan, Fei Yao, Jiantao Wang   +13 more
wiley   +1 more source