Results 221 to 230 of about 15,573 (263)
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Purification and Culture of Retinal Ganglion Cells
Cold Spring Harbor Protocols, 2013Retinal ganglion cells (RGCs) are the neurons that extend axons through the optic nerve, connecting and transmitting information from the retina to the brain. In mammals, RGCs receive information from bipolar and amacrine cells and synapse onto target cells in the lateral geniculate nucleus (LGN) as well as the superior colliculus.
Alissa, Winzeler, Jack T, Wang
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Current Biology
How do we perceive the beautiful and rich world around us? Light from the external environment is focused onto the retina, our visual sensory organ. Photons are captured by photoreceptors - light sensors within the retina - and converted into electrical signals. These electrical signals are transmitted to the brain through the optic nerve.
Akihiro, Matsumoto, Keisuke, Yonehara
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How do we perceive the beautiful and rich world around us? Light from the external environment is focused onto the retina, our visual sensory organ. Photons are captured by photoreceptors - light sensors within the retina - and converted into electrical signals. These electrical signals are transmitted to the brain through the optic nerve.
Akihiro, Matsumoto, Keisuke, Yonehara
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Hyperacuity in Cat Retinal Ganglion Cells
Science, 1986Cat X retinal ganglion cells that can resolve sine gratings of only 2.5 cycles per degree can nevertheless respond reliably to displacements of a grating of approximately 1 minute of arc. This is a form of hyperacuity comparable in magnitude to that seen in human vision.
R, Shapley, J, Victor
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Activation of autophagy in retinal ganglion cells
Journal of Neuroscience Research, 2008AbstractAutophagy has been shown to be activated in neuronal cells in response to injury and suggested to have a cell‐protective role in neurodegenerative diseases. In this study, we investigated the activation of autophagy in retinal ganglion cells (RGCs) following optic nerve transection (ONT) and evaluated its effect on RGC survival.
Seok Hwan, Kim +7 more
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Retinal Ganglion Cell Axon Fractionation
2023Retinal ganglion cell (RGC) axon regeneration in mammals can be stimulated through gene knockouts, pharmacological agents, and biophysical stimulation. Here we present a fractionation method to isolate regenerating RGC axons for downstream analysis using immunomagnetic separation of cholera toxin subunit B (CTB)-bound RGC axons.
Sean D, Meehan, Sanjoy, Bhattacharya
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Culture of rat retinal ganglion cells
Journal of Huazhong University of Science and Technology [Medical Sciences], 2011This study aimed to modify the mixed and purified culture of rat retinal ganglion cells (RGCs) in vitro. The retinae of 1-3 day old Sprague-Dawley (SD) rats were separated bluntly into two layers: inner layer and outer layer, under a surgical microscope. Retinal cells isolated from different layers (inner layer, outer layer and whole retinal tissue) by
Zhirong, Xu +4 more
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Topography of pig retinal ganglion cells
Journal of Comparative Neurology, 2005AbstractIn the present work we analyzed the distribution of retinal ganglion cells (RGCs) in the pig retina. RGCs were retrogradely labeled in vivo by injecting Fluoro‐Gold into the optic nerve. RGC density and the distribution of RGCs in terms of soma size were analyzed. Different regions of the porcine retina were identified following analysis of the
Mónica, Garcá +3 more
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Feature Detection by Retinal Ganglion Cells
Annual Review of Vision Science, 2022Retinal circuits transform the pixel representation of photoreceptors into the feature representations of ganglion cells, whose axons transmit these representations to the brain. Functional, morphological, and transcriptomic surveys have identified more than 40 retinal ganglion cell (RGC) types in mice.
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Peptides influence retinal ganglion cells
Neuroscience Letters, 1981Neurotensin, substance P and (D-Ala2, Met5)-enkephalinamide were iontophoresed onto ganglion cells of the amphibian retina. Substance P and neurotensin were found to be excitatory while (D-Ala2, Met5)-enkephalinamide suppressed all types of ganglion cells. These findings are consistent with a functional role for peptides in the vertebrate retina.
E, Dick, R F, Miller
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Towards Retinal Ganglion Cell Regeneration
Regenerative Medicine, 2012Traumatic optic nerve injury and glaucoma are among the leading causes of incurable vision loss across the world. What is worse, neither pharmacological nor surgical interventions are significantly effective in reversing or halting the progression of vision loss.
Huasong, Gao +7 more
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