Results 161 to 170 of about 399,940 (338)

Retinal Viral Gene Therapy: Impact of Route of Administration on Serious Adverse Events—A Systematic Review

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To explore the prevalence of serious adverse events (SAEs) associated with retinal viral gene therapy and to examine trends influencing SAE occurrences in human gene therapy surgeries and pre‐clinical animal trials. Methods Literature review was performed to identify peer‐reviewed human and animal studies relevant to viral gene ...
Aubrey Berger, Ciera D. Johnson, Alan D. Marmorstein, Brittni A. Scruggs   +3 more
wiley   +1 more source

Characterization of protein kinase C β isoform's action on retinoblastoma protein phosphorylation, vascular endothelial growth factor-induced endothelial cell proliferation, and retinal neovascularization [PDF]

, 2002
Kiyoshi Suzuma, Noriko Takahara, Izumi Suzuma, Keiji Isshiki, Kohjiro Ueki, Michael Leitges, Lloyd Paul Aiello, George L. King   +7 more
openalex   +1 more source

Ten‐Year Incidence, Risk Factors and Progression Rate of Macular Atrophy in Neovascular Age‐Related Macular Degeneration

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To evaluate the 10‐year cumulative incidence, progression rates, and risk factors for macular atrophy (MA) in neovascular age‐related macular degeneration (nAMD) patients receiving long‐term anti‐vascular endothelial growth factor (VEGF) therapy.
Francesco Romano, Marco Casaluci, Antonio Valastro, Matteo Airaldi, Paolo Milella, Francesco Pozzo Giuffrida, Elisa Cozzi, Andrea Aretti, Kelvin YC Teo, Chui Ming Gemmy Cheung, Marco Nassisi, Francesco Viola, Giovanni Staurenghi, Alessandro Invernizzi   +13 more
wiley   +1 more source

Knockout of insulin and IGF-1 receptors on vascular endothelial cells protects against retinal neovascularization [PDF]

, 2003
Tatsuya Kondo, David Vicent, Kiyoshi Suzuma, Masashi Yanagisawa, George L. King, Martin Holzenberger, C. Ronald Kahn   +6 more
openalex   +1 more source

The roles of macrophage migration inhibitory factor in retinal diseases

Neural Regeneration Research
Macrophage migration inhibitory factor (MIF), a multifunctional cytokine, is secreted by various cells and participates in inflammatory reactions, including innate and adaptive immunity. There are some evidences that MIF is involved in many vitreoretinal
Hongbing Zhang, Xianjiao Zhang, Hongsong Li, Bing Wang, Pei Chen, Jiamin Meng   +5 more
doaj   +1 more source

Evaluating the outcomes of pluripotent stem‐cell‐derived photoreceptor transplantation in retinal repair

The FEBS Journal, EarlyView.
Transplantation of stem cell‐derived photoreceptors in retinal repair. We summarize methods for differentiating stem cells and describe surgical techniques for transplanting photoreceptor precursors to restore visual function (A). The effectiveness of these techniques is assessed with behavioral (B) and in vitro assays (C) using mouse models that mimic
Darin Zerti, Birthe Dorgau, Evelyne Sernagor, Lyle Armstrong, Majlinda Lako, Gerrit Hilgen   +5 more
wiley   +1 more source

Angiopoietin/Tek Interactions Regulate MMP-9 Expression and Retinal Neovascularization [PDF]

, 2003
Arup Das, William C. Fanslow, Douglas Pat Cerretti, Erin Warren, Nicholas Talarico, Paul McGuire   +5 more
openalex   +1 more source

Phenotyping of retinal neovascularization in ischemic retinal vein occlusion using wide field OCT angiography

Eye, 2020
Josef Huemer, Hagar Khalid, S. Wagner, L. Nicholson, D. J. Fu, D. Sim, P. Patel, K. Balaskas, R. Rajendram, P. Keane   +9 more
semanticscholar   +1 more source

Current Progress of Tissue Engineering With Stem Cells in Urology Updated Review in 2025

International Journal of Urology, EarlyView.
ABSTRACT Tissue engineering, a key component of regenerative medicine, aims to restore the structure and function of damaged organs using combinations of cells, scaffolds, and bioactive factors. In urology, the integration of stem cell biology has fueled significant progress in preclinical models for kidney, bladder, and urethral regeneration ...
Kenichi Kobayashi, Tsunehito Horii, Akinori Wada, Kazuaki Yamanaka, Akeo Hagiwara, Susumu Kageyama   +5 more
wiley   +1 more source

Dysregulation of lncRNA OIP5‐AS1 participants in the progression of diabetic retinopathy and affects the proliferation in retinal vascular endothelial cell

Journal of Diabetes Investigation, EarlyView.
OIP5‐AS1 was down‐regulated in T2DM‐DR patients and regulated cellular functions via targeting miR‐181a‐5p. ABSTRACT Aims This study was to ascertain the clinical performance of OIP5‐AS1 in diabetic retinopathy (DR) and its molecular mechanism in the disease progression. Materials and Methods Subjects included 85 healthy controls, 79 patients with type
Ziwen Yin, Jingyun Dong, Yachao Meng, Zhiqiang Yang, Chunhong Zhao, Qiuyun Wu   +5 more
wiley   +1 more source