Results 31 to 40 of about 396,361 (329)
eLife, 2019 Constitutive TGFβ signaling is important in maintaining retinal neurons and blood vessels and is a factor contributing to the risk for age-related macular degeneration (AMD), a retinal disease involving neurodegeneration and microglial activation.
Wenxin Ma +6 more
doaj +2 more sources
Effects of nuclear factor κB expression on retinal neovascularization and apoptosis in a diabetic retinopathy rat model [PDF]
International Journal of Ophthalmology, 2015 AIM:To investigate the expression and role of nuclear factor κB (NF-κB) in diabetic retinopathy (DR) and its relationship with neovascularization and retinal cell apoptosis.METHODS: A total of 80 male Wistar rats were randomly assigned to control (4, 8 ...
Ning Jiang +3 more
doaj +2 more sources
Optical Coherence Tomography Features of Active and Inactive Retinal Neovascularization in Proliferative Diabetic Retinopathy [PDF]
, 2016 PURPOSE: To describe spectral domain-optical coherence tomography features of retinal neovascularization in proliferative diabetic retinopathy and thus to identify novel signs of new vessel activity. METHODS: Retrospective, cross-sectional study.
Egan, CA +6 more
core +3 more sources
Cyclic AMP Response Element Binding Protein Mediates Pathological Retinal Neovascularization via Modulating DLL4-NOTCH1 Signaling [PDF]
EBioMedicine, 2015 Retinal neovascularization is the most common cause of moderate to severe vision loss in all age groups. Despite the use of anti-VEGFA therapies, this complication continues to cause blindness, suggesting a role for additional molecules in retinal ...
Nikhlesh K. Singh +3 more
openalex +3 more sources
Ocular Syphilis with Retinal and Disc Neovascularization Treated with Bevacizumab: A Case Report
Case Reports in Ophthalmology, 2023 We report the findings observed in a young woman with ocular syphilis complicated with retinal and disc neovascularization successfully treated with intravitreal bevacizumab.
Lucia Comastri +4 more
doaj +1 more source
Frontiers in Immunology, 2022 Inflammation plays a pivotal role in ischemia-induced retinal neovascularization. Targeting microglia/macrophage-based neuroinflammation presents a promising therapeutic strategy.
Xiaowei Sun +5 more
semanticscholar +1 more source
Frontiers in Molecular Neuroscience, 2023 Microglia are the primary resident retinal macrophages that monitor neuronal activity in real-time and facilitate angiogenesis during retinal development. In certain retinal diseases, the activated microglia promote retinal angiogenesis in hypoxia stress
Xue-Yan Fu +5 more
semanticscholar +1 more source
Journal of Clinical Investigation, 2021 Therapies targeting VEGF have proven only modestly effective for the treatment of proliferative sickle cell retinopathy (PSR), the leading cause of blindness in patients with sickle cell disease.
Jing Zhang +19 more
semanticscholar +1 more source
Nattokinase Attenuates Retinal Neovascularization Via Modulation of Nrf2/HO-1 and Glial Activation
Investigative Ophthalmology and Visual Science, 2021 Purpose Nattokinase (NK), an active ingredient extracted from traditional food Natto, has been studied for prevention and treatment of cardiovascular diseases due to various vasoprotective effects, including fibrinolytic, antihypertensive, anti ...
Zijing Huang +9 more
semanticscholar +1 more source
Case Reports in Ophthalmological Medicine, 2021 We report the rescue effect of intravitreal aflibercept injections on retinal neovascularization and macular edema due to Eales disease. Case 1 was a 36-year-old female. Intravitreal aflibercept was administered as rescue therapy after persistent retinal
Ning-Yi Hsia +6 more
doaj +1 more source