Results 31 to 40 of about 38,468 (270)

Therapeutic effect against retinal neovascularization in a mouse model of oxygen-induced retinopathy: bone marrow-derived mesenchymal stem cells versus Conbercept

BMC Ophthalmology, 2020
Background To study the therapeutic effect of bone marrow-derived mesenchymal stem cells (BMSC) against retinal neovascularization and to compare with anti-vascular endothelial growth factor (VEGF) therapy.
Wei Xu, Weijing Cheng, Xiaoyuan Cui, Guoxing Xu   +3 more
doaj   +1 more source

Endothelium Expression of Bcl-2 Is Essential for Normal and Pathological Ocular Vascularization.

PLoS ONE, 2015
Bcl-2 is an anti-apoptotic protein with important roles in vascular homeostasis and angiogenesis. Mice globally lacking Bcl-2 (Bcl-2 -/-) are small in stature and succumb to renal failure shortly after weaning as a result of renal hypoplasia/cystic ...
Ismail S Zaitoun, Ryan P Johnson, Nasim Jamali, Reem Almomani, Shoujian Wang, Nader Sheibani, Christine M Sorenson   +6 more
doaj   +1 more source

Rapid Regression of Exudative Maculopathy in Idiopathic Retinitis, Vasculitis, Aneurysms and Neuroretinitis Syndrome after Intravitreal Ranibizumab

Case Reports in Ophthalmology, 2012
The idiopathic retinitis, vasculitis, aneurysms and neuroretinitis syndrome is a rare retinal vascular disorder characterized by multiple leaking aneurysmal dilations, retinal vasculitis, neuroretinitis and peripheral vascular ischemia.
Cristina Marín-Lambíes, Roberto Gallego-Pinazo, David Salom, Javier Navarrete, Manuel Díaz-Llopis   +4 more
doaj   +1 more source

Spectrum of peripheral retinal ischemia in Wyburn-Mason syndrome

American Journal of Ophthalmology Case Reports, 2020
Purpose: We report two cases of Wyburn-Mason syndrome that illustrate the spectrum of peripheral retinal ischemia seen in this condition. Observations: A 12-year-old female presented with a retinal arteriovenous malformation and sclerotic vessels ...
Blake Fortes, MD, James Lin, MD, Supalert Prakhunhungsit, MD, Carlos Mendoza-Santiesteban, MD, Audina M. Berrocal, MD   +4 more
doaj   +1 more source

Toward Wireless Implantable Robotic Systems Driven by Magnetic Field for Personalized Therapy

Advanced Robotics Research, EarlyView.
Robotic materials are playing an increasingly vital role in enabling sensing and actuation at small scales. This perspective highlights recent advances in magnetic materials and magnetically actuated devices for wireless sensing, actuation, and energy harvesting toward implantable robotic systems for closed‐loop therapy.
Yusheng Wang, Ruijian Ge, Xiaoguang Dong
wiley   +1 more source

Bilateral Hypertensive Retinopathy Complicated with Retinal Neovascularization: Panretinal Photocoagulation or Intravitreal Anti-VEGF Treatment

Case Reports in Ophthalmology, 2014
Purpose: To present the case of a patient with bilateral hypertensive retinopathy complicated with retinal neovascularization who received anti-VEGF intravitreal injection in one eye and panretinal photocoagulation (PRP) in the fellow eye.
Odysseas Georgiadis, Stamatina A. Kabanarou, Georgios Batsos, Elias Feretis, Tina Xirou   +4 more
doaj   +1 more source

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

Advanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang, Linghua Zeng, Kunkun Zou, Keying Lin, Fangting Yao, Jinglun Song, Shumeng Zhang, Hanshu Feng, Zhichao Yang, Chunlei Wang, Hongtao Diao, Xue Kong, Tengfei Pan, Joonki Kim, Tianqi Duo, Linqiang Li, Yu Bian   +16 more
wiley   +1 more source

Computer-aided quantification of retinal neovascularization [PDF]

Angiogenesis, 2009
Rodent models of retinal angiogenesis play a pivotal role in angiogenesis research. These models are a window to developmental angiogenesis, to pathological retinopathy, and are also in vivo tools for anti-angiogenic drug screening in cancer and ophthalmic research.
Stahl, Andreas, Connor, Kip M., Sapieha, Przemyslaw, Willett, Keirnan L., Krah, Nathan M., Dennison, Roberta J., Chen, Jing, Guerin, Karen I., Smith, Lois E. H.   +8 more
openaire   +3 more sources

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source

Neovascularization Detection and Localization in Fundus Images Using Deep Learning

Sensors, 2021
Proliferative Diabetic Retinopathy (PDR) is a severe retinal disease that threatens diabetic patients. It is characterized by neovascularization in the retina and the optic disk. PDR clinical features contain highly intense retinal neovascularization and
Michael Chi Seng Tang, Soo Siang Teoh, Haidi Ibrahim, Zunaina Embong   +3 more
doaj   +1 more source