Results 51 to 60 of about 402,915 (338)

Concurrent management of myopic choroidal neovascularization and rhegmatogenous retinal detachment with intravitreal antivascular endothelial growth factor during primary retinal detachment repair

Indian Journal of Ophthalmology, 2018
We report concurrent management of rhegmatogenous retinal detachment and myopic choroidal neovascularization in the left eye of a 24-year-old female who presented with sudden dimness of vision due to retinal detachment and choroidal neovascularization ...
Kumar Saurabh, Rupak Roy, Nicey Roy Thomas, Maitreyi Chowdhury   +3 more
doaj   +1 more source

Disruption of profilin1 function suppresses developmental and pathological retinal neovascularization

Journal of Biological Chemistry, 2020
Angiogenesis-mediated neovascularization in the eye is usually associated with visual complications. Pathological angiogenesis is particularly prominent in the retina in the settings of proliferative diabetic retinopathy, in which it can lead to ...
D. Gau, L. Vignaud, Abigail Allen, Zhijian Guo, J. Sahel, David N. Boone, D. Koes, X. Guillonneau, P. Roy   +8 more
semanticscholar   +1 more source

Bim expression in endothelial cells and pericytes is essential for regression of the fetal ocular vasculature. [PDF]

PLoS ONE, 2017
Apoptosis plays a central role in developmental and pathological angiogenesis and vessel regression. Bim is a pro-apoptotic Bcl-2 family member that plays a prominent role in both developmental and pathological ocular vessel regression, and ...
Shoujian Wang, Ismail S Zaitoun, Ryan P Johnson, Nasim Jamali, Zafer Gurel, Catherine M Wintheiser, Andreas Strasser, Volkhard Lindner, Nader Sheibani, Christine M Sorenson   +9 more
doaj   +1 more source

Mechanism of piR-1245/PIWI-like protein-2 regulating Janus kinase-2/signal transducer and activator of transcription-3/vascular endothelial growth factor signaling pathway in retinal neovascularization

Neural Regeneration Research, 2023
Inhibiting retinal neovascularization is the optimal strategy for the treatment of retina-related diseases, but there is currently no effective treatment for retinal neovascularization.
Yong Yu, Li-Kun Xia, Yu Di, Qing-Zhu Nie, Xiao-Long Chen   +4 more
doaj   +1 more source

Complement C3 variant and the risk of age-related macular degeneration [PDF]

, 2007
Background: Age-related macular degeneration is the most common cause of blindness in Western populations. Susceptibility is influenced by age and by genetic and environmental factors.
Armbrecht, AM, Bird, AC, Clayton, DG, Deary, IJ, Dhillon, B, Genetic Factors AMD Study G, Hayward, C, Khan, JC, Matharu, BK, Moore, AT, Morgan, J, Redmond, E, Sepp, T, Shahid, H, Thurlby, DA, Wright, AF, Yates, JRW   +16 more
core   +1 more source

Vascular cell-adhesion molecule 1 (VCAM-1) regulates JunB-mediated IL-8/CXCL1 expression and pathological neovascularization

Communications Biology, 2023
Vascular adhesion molecules play an important role in various immunological disorders, particularly in cancers. However, little is known regarding the role of these adhesion molecules in proliferative retinopathies.
Geetika Kaur, Deepti Sharma, Shivantika Bisen, Chandra Sekhar Mukhopadhyay, Katherine Gurdziel, Nikhlesh K. Singh   +5 more
doaj   +1 more source

Laser treatment in diabetic retinopathy [PDF]

, 2007
Diabetic retinopathy is a leading cause of visual impairment and blindness in developed countries due to macular edema and proliferative diabetic retinopathy (PDR). For both complications laser treatment may offer proven therapy: the Diabetic Retinopathy
Akduman L, Aljoscha S. Neubauer, Arend O, Bandello F, Benson WE, Chew EY, Davies N, Ferris, Ferris F, Friberg TR, Gabel VP, Gallemore RP, Giovannini A, Gupta V, Hainsworth DP, Jaffe GJ, Kinyoun J, Klein R, Kroll P, Ladas ID, Laursen ML, Lee CM, Lewis H, Luttrull JK, Maeshima K, Michael W. Ulbig, Neubauer AS, Parolini B, Puliafito CA, Sanchez-Tocino H, Schatz H, Shahidi M, Shimura M, Ulbig MR, Ulbig MW, Ulbig MW, Xu X   +36 more
core   +1 more source

Peripheral Retinal Neovascularization with Vitreous Hemorrhage in HIV Retinopathy

Case Reports in Ophthalmology, 2017
We report a case of peripheral retinal neovascularization and vitreous hemorrhage in the setting of HIV retinopathy that can serve to extend the clinical spectrum of this condition.
Kim Jiramongkolchai, Tin Yan Alvin Liu, J. Fernando Arevalo   +2 more
doaj   +1 more source

Combining Fine- and Coarse-Grained Classifiers for Diabetic Retinopathy Detection

, 2020
Visual artefacts of early diabetic retinopathy in retinal fundus images are usually small in size, inconspicuous, and scattered all over retina. Detecting diabetic retinopathy requires physicians to look at the whole image and fixate on some specific ...
Adrià Recasens, DY Carson Lam, E Decencière, G Quellec, J Amin, L Seoud, MD Abràmoff, MU Akram, N Ramachandran, P Costa, R Welikala, V Gulshan, Z Wang, Ze Yang   +13 more
core   +1 more source

Diabetic retinopathy: could the alpha-1 antitrypsin be a therapeutic option? [PDF]

, 2014
Diabetic retinopathy is one of the most important causes of blindness. The underlying mechanisms of this disease include inflammatory changes and remodeling processes of the extracellular-matrix (ECM) leading to pericyte and vascular endothelial cell ...
Chuluyan, Hector Eduardo, Gallo, Juan Eduardo Maria, Ortiz, Gustavo Alfredo, Salica, Juan Pablo   +3 more
core   +1 more source