Results 81 to 90 of about 386,190 (246)

Complement C3 variant and the risk of age-related macular degeneration [PDF]

, 2007
Background: Age-related macular degeneration is the most common cause of blindness in Western populations. Susceptibility is influenced by age and by genetic and environmental factors.
Armbrecht, AM, Bird, AC, Clayton, DG, Deary, IJ, Dhillon, B, Genetic Factors AMD Study G, Hayward, C, Khan, JC, Matharu, BK, Moore, AT, Morgan, J, Redmond, E, Sepp, T, Shahid, H, Thurlby, DA, Wright, AF, Yates, JRW   +16 more
core   +1 more source

Wide-field angiography in retinal vein occlusions

International Journal of Retina and Vitreous, 2019
Background Retinal vein occlusion (RVO) is the second most common retinal vascular disease after diabetic retinopathy. It can result in significant visual loss from complications like macula edema, retinal and iris neovascularization, and vitreous ...
Colin S. Tan, Kelvin Z. Li, SriniVas R. Sadda   +2 more
doaj   +1 more source

Segmentation of Retinal Blood Vessels Using Deep Learning [PDF]

arXiv, 2023
The morphology of retinal blood vessels can indicate various diseases in the human body, and researchers have been working on automatic scanning and segmentation of retinal images to aid diagnosis. This project compares the performance of four neural network architectures in segmenting retinal images, using a combined dataset from different databases ...
arxiv  

Cnidium officinale extract and butylidenephthalide inhibits retinal neovascularization in vitro and in vivo

BMC Complementary and Alternative Medicine, 2016
BackgroundRetinal neovascularization, which is the pathological growth of new blood vessels, is associated with retinopathy of prematurity, neovascular age-related macular degeneration, diabetic retinopathy and retinal vein occlusion.
Y. Lee, Yu-Ri Lee, Chan-Sik Kim, K. Jo, E. Sohn, Jin Sook Kim, Junghyun Kim   +6 more
semanticscholar   +1 more source

Combining Fine- and Coarse-Grained Classifiers for Diabetic Retinopathy Detection

, 2020
Visual artefacts of early diabetic retinopathy in retinal fundus images are usually small in size, inconspicuous, and scattered all over retina. Detecting diabetic retinopathy requires physicians to look at the whole image and fixate on some specific ...
Adrià Recasens, DY Carson Lam, E Decencière, G Quellec, J Amin, L Seoud, MD Abràmoff, MU Akram, N Ramachandran, P Costa, R Welikala, V Gulshan, Z Wang, Ze Yang   +13 more
core   +1 more source

Laser treatment in diabetic retinopathy [PDF]

, 2007
Diabetic retinopathy is a leading cause of visual impairment and blindness in developed countries due to macular edema and proliferative diabetic retinopathy (PDR). For both complications laser treatment may offer proven therapy: the Diabetic Retinopathy
Akduman L, Aljoscha S. Neubauer, Arend O, Bandello F, Benson WE, Chew EY, Davies N, Ferris, Ferris F, Friberg TR, Gabel VP, Gallemore RP, Giovannini A, Gupta V, Hainsworth DP, Jaffe GJ, Kinyoun J, Klein R, Kroll P, Ladas ID, Laursen ML, Lee CM, Lewis H, Luttrull JK, Maeshima K, Michael W. Ulbig, Neubauer AS, Parolini B, Puliafito CA, Sanchez-Tocino H, Schatz H, Shahidi M, Shimura M, Ulbig MR, Ulbig MW, Ulbig MW, Xu X   +36 more
core   +1 more source

Dietary Compound Chrysin Inhibits Retinal Neovascularization with Abnormal Capillaries in db/db Mice

Nutrients, 2016
Diabetic retinopathy (DR) develops in a significant proportion of patients with chronic diabetes, characterized by retinal macular edema and abnormal retinal vessel outgrowth leading to vision loss.
Min-Kyung Kang, Sin-Hye Park, Yun-Ho Kim, Eun‐Jung Lee, L. Antika, Dong Yeon Kim, Yean-Jung Choi, Young‐Hee Kang   +7 more
semanticscholar   +1 more source

Mild endoplasmic reticulum stress promotes retinal neovascularization via induction of BiP/GRP78. [PDF]

PLoS ONE, 2013
Endoplasmic reticulum (ER) stress occurs as a result of accumulation of unfolded or misfolded proteins in the ER and is involved in the mechanisms of various diseases, such as cancer and neurodegeneration. The goal of the present study was to clarify the
Shinsuke Nakamura, Haruka Takizawa, Masamitsu Shimazawa, Yuhei Hashimoto, Sou Sugitani, Kazuhiro Tsuruma, Hideaki Hara   +6 more
doaj   +1 more source

Targeted Thrombospondin-1 Expression in Ocular Vascular Development and Neovascularization

Frontiers in Cell and Developmental Biology, 2021
Tight regulation of positive and negative regulators of angiogenesis is essential, particularly in the eye where their dysregulation can lead to vision loss.
Christine M. Sorenson, Christine M. Sorenson, Shoujian Wang, Soesiawati R. Darjatmoko, Zafer Gurel, Bo Liu, Bo Liu, Nader Sheibani, Nader Sheibani, Nader Sheibani, Nader Sheibani   +10 more
doaj   +1 more source

Lebecetin, a C‐type lectin, inhibits choroidal and retinal neovascularization

The FASEB Journal, 2017
Angiogenesis is a cause of visual impairment and blindness in the wet form of age‐related macular degeneration and in ischemic retinopathies. Current therapies include use of anti‐VEGF agents to reduce choroidal neovascularization (CNV) and edema.
Fadoua Montassar, Marie Darche, A. Blaizot, S. Augustin, Jean-Baptiste Conart, A. Millet, M. Elayeb, J. Sahel, A. R. Goazigo, F. Sennlaub, N. Marrakchi, E. Messadi, X. Guillonneau   +12 more
semanticscholar   +1 more source