Results 81 to 90 of about 385,405 (300)

Real‐world outcomes of aflibercept 8 mg in patients previously treated for neovascular age‐related macular degeneration

Acta Ophthalmologica, EarlyView.
Abstract Purpose To evaluate visual, anatomical and safety outcomes of aflibercept 8 mg in previously treated patients with neovascular age‐related macular degeneration (nAMD). Methods This retrospective study included nAMD patients switched to aflibercept 8 mg from prior anti‐VEGF therapies at Sahlgrenska University Hospital between February 2024 and ...
Imadeddin Abu Ishkheidem, Esra Inci, Martin Breimer, Sofia Töyrä Silfverswärd, Madeleine Zetterberg, Marita Andersson Grönlund   +5 more
wiley   +1 more source

Formononetin, an active compound of Astragalus membranaceus (Fisch) Bunge, inhibits hypoxia-induced retinal neovascularization via the HIF-1α/VEGF signaling pathway

Drug Design, Development and Therapy, 2016
Background It has been reported that formononetin (FMN), one of the main ingredients from famous traditional Chinese medicine “Huang-qi” (Astragalus membranaceus [Fisch] Bunge) for Qi-tonifying, exhibits the effects of immunomodulation and tumor growth ...
Jianming Wu, Xiao Ke, Na Ma, Wei Wang, Weiding Fu, Hongcheng Zhang, Man-xi Zhao, Xiaoping Gao, Xiaofeng Hao, Zhirong Zhang   +9 more
semanticscholar   +1 more source

Fluid/function correlation using AI‐based quantification versus central subfield thickness in treatment‐naïve and pre‐treated patients with neovascular AMD in a real‐world setting

Acta Ophthalmologica, EarlyView.
Abstract Purpose To investigate the association between best‐corrected visual acuity (BCVA) and quantitative macular fluid volumes, compared to central subfield thickness (CST) in treatment‐naïve and previously treated patients with active neovascular age‐related macular degeneration (nAMD).
Anna Eidenberger, Gregor S. Reiter, Virginia Mares, Sophie Frank‐Publig, Philipp Fuchs, Magdalena Baratsits, Markus Gumpinger, Georg Faustmann, Alexandra Miere, Catherine Creuzot‐Garcher, Ulrike Scheschy, Laurent Kodjikian, Vincent Gualino, Benjamin Wolff, Stefan Sacu, Ursula Schmidt‐Erfurth   +15 more
wiley   +1 more source

Characteristics of Retinal Neovascularization in Proliferative Diabetic Retinopathy Imaged by Optical Coherence Tomography Angiography.

Investigative Ophthalmology and Visual Science, 2016
Purpose To characterize the morphology of neovascularization at the disc (NVD) and neovascularization elsewhere (NVE) in treatment-naïve or previously treated proliferative diabetic retinopathy (PDR) patients using optical coherence tomography (OCT ...
Akihiro Ishibazawa, T. Nagaoka, H. Yokota, A. Takahashi, Tsuneaki Omae, Youngseok Song, Tatsuhisa Takahashi, A. Yoshida   +7 more
semanticscholar   +1 more source

Power and clinical utility of mesopic microperimetry analysis strategies in age‐related macular degeneration

Acta Ophthalmologica, EarlyView.
Abstract Purpose This study evaluates whether mesopic microperimetry (MMP) provides a more robust measure of retinal function compared to visual acuity (VA) in age‐related macular degeneration (AMD) clinical trials, with a focus on optimal analysis strategies. Method Fellow‐eyes of unilateral neovascular AMD were prospectively studied.
Francesco Cinque, Jeroen Pas, Mahfam Shahabi, Laurens Sluijterman, Sofie ten Brink, Anita de Breuk, Thomas J. Heesterbeek, Caroline Klaver, Carel Hoyng, Yara Lechanteur   +9 more
wiley   +1 more source

Spectral domain-optical coherence tomography retinal biomarkers in choroidal neovascularization of multifocal choroiditis, myopic choroidal neovascularization, and idiopathic choroidal neovascularization [PDF]

, 2021
Rui Gao, Jingxue Ma, Zhengwei Zhang, Qingli Shang, Jialiang Duan   +4 more
openalex   +1 more source

Neovascular age‐related macular degeneration without drusen

Acta Ophthalmologica, EarlyView.
Abstract Purpose To describe the clinical characteristics and 1‐year follow‐up of patients with neovascular AMD (nAMD) without drusen in either eye. Methods This is a multicentre retrospective cohort study in three tertiary referral centres in The Netherlands. We included patients of 55 years or older with nAMD in one or both eyes, without the presence
Marc J. Sirks, Elon H. C. van Dijk, Husein Ghalayini, Somayeh Bazdar, WeiFeng Yu, Suzanne Yzer, José P. Martinez Ciriano, Reinier O. Schlingemann, Roselie M. H. Diederen, Camiel J. F. Boon   +9 more
wiley   +1 more source

Cnidium officinale extract and butylidenephthalide inhibits retinal neovascularization in vitro and in vivo

BMC Complementary and Alternative Medicine, 2016
BackgroundRetinal neovascularization, which is the pathological growth of new blood vessels, is associated with retinopathy of prematurity, neovascular age-related macular degeneration, diabetic retinopathy and retinal vein occlusion.
Y. Lee, Yu-Ri Lee, Chan-Sik Kim, K. Jo, E. Sohn, Jin Sook Kim, Junghyun Kim   +6 more
semanticscholar   +1 more source

Pregnancy as a risk factor for central serous chorioretinopathy: A systematic review and meta‐analysis

Acta Ophthalmologica, EarlyView.
Abstract Purpose Pregnancy induces significant changes in the body, including increased peripheral and choroidal blood perfusion and an increased systemic corticosteroid level. Here, we systematically reviewed the evidence on pregnancy as a risk factor for developing central serous chorioretinopathy (CSC) and conducted a meta‐analysis to obtain a ...
Nathalie Skovgaard Eriksen, Zainab Fakhril‐din, Riccardo Fasana, Rodrigo Anguita, Elon H. C. van Dijk, Lorenzo Ferro Desideri, Jakob Grauslund, Michael Stormly Hansen, Oliver Niels Klefter, Armin Motaabbed, Line Petersen, Prithvi Ramtohul, Mehmet Cem Sabaner, Osman Savran, Miklos Schneider, Yousif Subhi   +15 more
wiley   +1 more source

Receptor-Interacting Protein Kinase-3 Expression Impacts Ocular Vascular Development and Pathological Neovascularization

Cells
Functional cell death pathways are essential for normal ocular vascular development and tissue homeostasis. As our understanding of necrosis-based cell death pathways has expanded, the inclusion of regulated forms, including necroptosis, ferroptosis, and
Yong-Seok Song, Shoujian Wang, SunYoung Park, Barbara Hanna, Kelsey J. Johnson, Soesiawati R. Darjatmoko, Mohammad Ali Saghiri, Ali Mohammad Saghiri, Bo Liu, Christine M. Sorenson, Nader Sheibani   +10 more
doaj   +1 more source