Results 131 to 140 of about 91,639 (372)
Investigative Ophthalmology and Visual Science, 2015 PURPOSE To seek pathways of retinal pigment epithelium (RPE) fate in age-related macular degeneration via a morphology grading system; provide nomenclature, visualization targets, and metrics for clinical imaging and model systems.
E. Zanzottera +5 more
semanticscholar +1 more source
Investigative Ophthalmology and Visual Science, 2015 PURPOSE Lipofuscin (LF) and melanolipofuscin (MLF) of the retinal pigment epithelium (RPE) are the principal sources of autofluorescence (AF) signals in clinical fundus-AF imaging.
T. Ach +5 more
semanticscholar +1 more source
Multiclass segmentation as multitask learning for drusen segmentation in retinal optical coherence tomography [PDF]
arXiv, 2019 Automated drusen segmentation in retinal optical coherence tomography (OCT) scans is relevant for understanding age-related macular degeneration (AMD) risk and progression. This task is usually performed by segmenting the top/bottom anatomical interfaces that define drusen, the outer boundary of the retinal pigment epithelium (OBRPE) and the Bruch's ...
arxiv
Bayesian Optimization in Bioprocess Engineering—Where Do We Stand Today?
Biotechnology and Bioengineering, EarlyView.ABSTRACT Bayesian optimization is a stochastic, global black‐box optimization algorithm. By combining Machine Learning with decision‐making, the algorithm can optimally utilize information gained during experimentation to plan further experiments—while balancing exploration and exploitation.
Florian Gisperg +5 more
wiley +1 more source
Indian Journal of Ophthalmology, 2019 Congenital hypertrophy of retinal pigment epithelium (CHRPE) is a benign, pigmented, flat lesion arising from the retinal pigment epithelium (RPE). In this study, we describe optical coherence tomography angiography (OCTA) features of two eyes with ...
P Mahesh Shanmugam +5 more
doaj +1 more source
The Channel Attention based Context Encoder Network for Inner Limiting Membrane Detection [PDF]
arXiv, 2019 The optic disc segmentation is an important step for retinal image-based disease diagnosis such as glaucoma. The inner limiting membrane (ILM) is the first boundary in the OCT, which can help to extract the retinal pigment epithelium (RPE) through gradient edge information to locate the boundary of the optic disc. Thus, the ILM layer segmentation is of
arxiv
Association of drusen deposition with choroidal intercapillary pillars in the aging human eye [PDF]
, 2004 PURPOSE. To determine the pattern of drusen accumulation with age and to investigate the initial sites of deposition and their relationship to choroidal capillaries in human donor eyes from the eye bank of Moorfields Eye Hospital.METHODS.
Al Hosaini, H +5 more
core +1 more source
Biotechnology Progress, EarlyView.Abstract Induced pluripotent stem cells (iPSCs) offer significant therapeutic potential, but cryopreservation challenges, particularly the reliance on cytotoxic Dimethyl Sulfoxide (Me2SO), hinder their clinical application. This review examines current cryopreservation practices in clinical and preclinical iPSC‐based therapies, highlighting the ...
Michael Dobruskin +2 more
wiley +1 more source
Retinal pigment epithelium changes in Kartagener syndrome
American Journal of Ophthalmology Case Reports, 2018 Purpose: We present the first case in the literature of a patient with Kartagener syndrome and ocular findings of nonexudative age-related macular degeneration. Observations: A 55-year-old woman with Kartagener syndrome and chronic angle closure glaucoma
Maria D. Garcia +4 more
doaj
U-Net with spatial pyramid pooling for drusen segmentation in optical coherence tomography [PDF]
arXiv, 2019 The presence of drusen is the main hallmark of early/intermediate age-related macular degeneration (AMD). Therefore, automated drusen segmentation is an important step in image-guided management of AMD. There are two common approaches to drusen segmentation. In the first, the drusen are segmented directly as a binary classification task.
arxiv