Results 131 to 140 of about 138,851 (338)

NLRP3 Upregulation in Retinal Pigment Epithelium in Age-Related Macular Degeneration

International Journal of Molecular Sciences, 2016
Inflammation and oxidative stress are involved in age-related macular degeneration (AMD) and possibly associated with an activation of neuronal apoptosis inhibitor protein/class II transcription activator of the Major Histocompatibility Complex (MHC ...
Yujuan Wang, J. Hanus, M. Abu-Asab, D. Shen, Alexander Ogilvy, J. Ou, X. Chu, G. Shi, Wei Li, Shusheng Wang, C. Chan   +10 more
semanticscholar   +1 more source

Secretory autophagy and epithelial‐to‐mesenchymal transition in cadaveric AMD samples: Novel pathways in disease progression

Acta Ophthalmologica, EarlyView.
Abstract Purpose To examine the presence of secretory autophagy and epithelial–mesenchymal transition (EMT) in the macular retinal pigment epithelium (RPE) of human cadaver eyes with different forms of age‐related macular degeneration (AMD). Methods Human cadaver macula samples representing dry and wet AMD, as well as age‐matched controls, were ...
Iswariyaraja Sridevi Gurubaran, Ali Koskela, Hanna Heloterä, Kai Kaarniranta   +3 more
wiley   +1 more source

Retinal findings in membranoproliferative glomerulonephritis

American Journal of Ophthalmology Case Reports, 2017
Purpose: To assess the evolution of retinal findings in patients with membranoproliferative glomerulonephritis (MPGN) by funduscopy, intravenous fluorescein angiography and optical coherence tomography. Observations: Three women and one man were followed
Ahmad M. Mansour, Luiz H. Lima, J. Fernando Arevalo, Miguel Hage Amaro, Virginia Lozano, Alaa Bou Ghannam, Errol W. Chan   +6 more
doaj   +1 more source

Complement C3 variant and the risk of age-related macular degeneration [PDF]

, 2007
Background: Age-related macular degeneration is the most common cause of blindness in Western populations. Susceptibility is influenced by age and by genetic and environmental factors.
Armbrecht, AM, Bird, AC, Clayton, DG, Deary, IJ, Dhillon, B, Genetic Factors AMD Study G, Hayward, C, Khan, JC, Matharu, BK, Moore, AT, Morgan, J, Redmond, E, Sepp, T, Shahid, H, Thurlby, DA, Wright, AF, Yates, JRW   +16 more
core   +1 more source

Interventions for submacular haemorrhage: A systematic review and network meta‐analysis of controversies—On behalf of the Spanish Vitreo‐Retinal Society (SERV)

Acta Ophthalmologica, EarlyView.
Abstract Purpose This systematic review aims to evaluate and synthesize the existing literature on the interventions used for submacular haemorrhage (SMH), highlighting the controversies and differences in clinical practice. Method A systematic review was conducted following the PRISMA guidelines.
Salvador Pastor‐Idoate, Pablo Redruello‐Guerrero, Laura de Juan Hernández, Gregorio Benites‐Narcizo, Mario Rivera‐Izquierdo, José García‐Arumí, José Carlos Pastor Jimeno   +6 more
wiley   +1 more source

Epinephrine, but not dexamethasone, induces apoptosis in human retinal pigment epithelium cells in vitro: Possible implications on the pathogenesis of central serous chorioretinopathy

Philippine Journal of Ophthalmology, 2004
Objective: The pathogenesis of central serous chorioretinopathy is poorly understood. It is believed to be due to dysfunction of the retinal pigment epithelium and/or choroid, and has been associated with elevated levels of epinephrine and administration
Santiago Antonio B. Sibayan, MD, PhD, Karin Kobuch, MD, Detlev Spiegel, MD, Elfriede Eckert, MTA, Rita Leser, MTA, Jan Monzer, PhD, Veit-Peter Gabel, MD   +6 more
doaj  

Humanin G (HNG) protects age-related macular degeneration (AMD) transmitochondrial ARPE-19 cybrids from mitochondrial and cellular damage. [PDF]

, 2017
Age-related macular degeneration (AMD) ranks third among the leading causes of visual impairment with a blindness prevalence rate of 8.7%. Despite several treatment regimens, such as anti-angiogenic drugs, laser therapy, and vitamin supplementation ...
Chwa, Marilyn, Cohen, Pinchas, Kenney, M Cristina, Kuppermann, Baruch D, Lu, Stephanie, Nashine, Sonali, Nesburn, Anthony B   +6 more
core   +1 more source

A model for de novo pigmentation of amelanotic retinal pigment epithelial cells

Acta Ophthalmologica, EarlyView.
Abstract Purpose Retinal Pigment Epithelial (RPE) cells perform critical functions in the visual cycle. Their melanin pigmentation, which is organized into specialized compartments – melanosomes, is highly critical for proper vision. A chemical method to induce pigmentation in a non‐pigmented model of ARPE‐19 cells was applied using L‐DOPA as a ...
Santosh Gupta, Lyubomyr Lytvynchuk, Taras Ardan, Hana Studenovska, Georgina Faura, Lars Eide, Ljubo Znaor, Slaven Erceg, Knut Stieger, Jan Motlik, Goran Petrovski   +10 more
wiley   +1 more source

JAPANESE QUAIL (COTURNIX JAPONICA) AS THE MODEL OF HUMAN AGING RETINAL PROCESSES. REPORT № 2. COMPARATIVE ANALYSIS OF THE COMPOSITION OF RETINOIDS ISOLATED FROM RETINAL PIGMENT EPITHELIUM OF HUMAN AND JAPANESE QUAIL EYES

Офтальмохирургия, 2015
Purpose. To compare the composition of retinoids of lipofuscin granules (LG) isolated from retinal pigment epithelium (RPE) of human cadaver eyes and Japanese quail. Material and methods.
M. A. Yakovleva, A. V. Zykova, P. M. Arbuhanova, N. N. Trofimova, S. A. Borzenok, M. A. Ostrovsky, P. P. Zak   +6 more
doaj  

Effects of cyclic adenosine 3,5-monophosphate on photoreceptor disc shedding and retinomotor movement. Inhibition of rod shedding and stimulation of cone elongation. [PDF]

, 1982
As a test of the hypothesis that cyclic nucleotides play a role in the regulation of retinomotor movements and disc shedding in the photoreceptor-pigment epithelial complex, we have used an in vitro eyecup preparation that sustains both disc shedding and
Besharse, J, BURNSIDE, Beth, Dunis, D
core   +1 more source