Results 141 to 150 of about 91,639 (372)
The unusual microtubule polarity in teleost retinal pigment epithelial cells. [PDF]
, 1988 In cells of the teleost retinal pigment epithelium (RPE), melanin granules disperse into the RPE cells long apical projections in response to light onset, and aggregate toward the base of the RPE cell in response to dark onset.
BURNSIDE, Beth, Troutt, L
core +1 more source
HN1 expression contributes to mitotic fidelity through Aurora A‐PLK1‐Eg5 axis
Cytoskeleton, EarlyView.Abstract Hematological and neurological expressed 1 (HN1) is homolog of Jupiter protein from Drosophila melanogaster where it functions as a microtubule‐associated protein. However, in mammalian cells, HN1 is associated partially with y‐tubulin in centrosomes, Stathmin for stabilizing microtubules, and Cdh1 for regulating Cyclin B1 for cell cycle ...
Gülseren Özduman +3 more
wiley +1 more source
Molecular Biology of the Cell, 2015 How autophagy is regulated in the postmitotic retinal pigment epithelium (RPE) is unclear. Visual cycle metabolites and cholesterol that accumulate in the RPE inhibit autophagic flux by activating acid sphingomyelinase (ASMase).
Kimberly A. Toops +4 more
semanticscholar +1 more source
The Heterotaxy Gene CCDC11 Is Important for Cytokinesis via RhoA Regulation
Cytoskeleton, EarlyView.ABSTRACT Mutations in CCDC11 (cfap53) have been identified in multiple patients with heterotaxy (Htx), a disorder of left–right (LR) patterning of the internal organs. In Xenopus, depletion of Ccdc11 causes defects in LR patterning, recapitulating the patient phenotype. Upon Ccdc11 depletion, monociliated cells of the Left–Right Organizer (LRO) exhibit
Saurabh S. Kulkarni +9 more
wiley +1 more source
Combined hamartoma of the retina and retinal pigment epithelium associated with optic coloboma
Clinical Ophthalmology, 2011 Nadyr Antonia Damasceno, Eduardo F DamascenoAbstract: The authors relate an uncommon case of combined hamartoma of the retina and retinal pigment epithelium associated with optic coloboma.Keywords: combined hamartoma of the retina and retinal pigment ...
Nadyr Antonia Damasceno +1 more
doaj
PLK4: Master Regulator of Centriole Duplication and Its Therapeutic Potential
Cytoskeleton, EarlyView.ABSTRACT Centrosomes catalyze the assembly of a microtubule‐based bipolar spindle, essential for the precise chromosome segregation during cell division. At the center of this process lies Polo‐Like Kinase 4 (PLK4), the master regulator that controls the duplication of the centriolar core to ensure the correct balance of two centrosomes per dividing ...
Muhammad Hamzah +2 more
wiley +1 more source
Revista Brasileira de Oftalmologia, 2014 Purpose: Register and compare anatomical changes, structural and quantitative found in optical coherence tomography Stratus and Topcon 3D in chronic users of chloroquine.
Celso Morita +5 more
doaj +1 more source
Quantitative phase imaging of retinal cells [PDF]
arXiv, 2017 The health of cells found in the inner retinal layers of the human eye is crucial to understand the onset of diseases of the retina such as macular degeneration and retinopathy. A challenge is to periodically image these cells in human eyes to detect abnormalities well before physiological and pathological changes occur.
arxiv
Clinical features of a novel TIMP-3 mutation causing Sorsby's fundus dystrophy: implications for disease mechanism [PDF]
, 2001 AIMS: To describe the phenotype in three family members affected by a novel mutation in the gene coding for the enzyme tissue inhibitor of metalloproteinase-3 (TIMP-3). METHODS: Three members of the same family were seen with a history of nyctalopia and
Barker, M.D. +6 more
core +2 more sources
ChemPlusChem, EarlyView.Gold nanoparticles (AuNPs) are widely used in biomedicine, electronics, catalysis, and environmental science. Conventional synthesis relies on harsh chemicals, driving interest in eco‐friendly methods using plants, bacteria, fungi, and algae. Biomolecules like polyphenols, proteins, and fatty acids aid nanoparticle synthesis under mild conditions. This
Youfeng Yue +3 more
wiley +1 more source