Results 181 to 190 of about 91,639 (372)
Coordination of IFT20 With Other IFT Components Is Required for Ciliogenesis
Journal of Clinical Laboratory Analysis, EarlyView.Intraflagellar transport is a bidirectional transport system essential for ciliogenesis. Using the IFT20 knockout cell lines established in this study, we found that IFT20 deficiency significantly impaired ciliogenesis and reduced cilium length. Further investigation revealed that IFT20 interacted with other IFT proteins and regulated their levels and ...
Weishu Wang +6 more
wiley +1 more source
Familial polyposis syndrome and achalasia in a young adult
JPGN Reports, EarlyView.Abstract We report the case of a 19‐year‐old White male diagnosed with familial adenomatous polyposis (FAP), Gardner's syndrome (GS) phenotype, status post total colectomy, who developed progressive dysphagia and weight loss. He was diagnosed with achalasia based on imaging and esophageal manometry.
Gabriella A. Lorusso Vivas +2 more
wiley +1 more source
Clinical &Experimental Ophthalmology, Volume 50, Issue 9, Page 1013-1024, December 2022., 2022 Abstract Background To evaluate the long‐term efficacy and safety of continued repeated low‐level red‐light (RLRL) therapy on myopia control over 2 years, and the potential rebound effect after treatment cessation. Methods The Chinese myopic children who originally completed the one‐year randomised controlled trial were enrolled.
Ruilin Xiong +13 more
wiley +1 more source
Optic Disc Pallor in Parkinson's Disease: A UK Biobank Study
Movement Disorders, EarlyView.Abstract Background Recent studies have suggested that retinal changes measured with optical coherence tomography are detectable in early Parkinson's disease (PD), highlighting the potential of ophthalmic biomarkers for diagnosis and monitoring. Objective We set out to investigate the relationship between optic disc pallor measured in fundoscopy images
Samuel Gibbon +3 more
wiley +1 more source
Ophthalmic imaging in diabetic retinopathy: A review
Clinical &Experimental Ophthalmology, Volume 50, Issue 9, Page 1082-1096, December 2022., 2022 Abstract Retinal imaging has been a key tool in the diagnosis, evaluation, management and documentation of diabetic retinopathy (DR) and diabetic macular oedema (DMO) for many decades. Imaging technologies have rapidly evolved over the last few decades, yielding images with higher resolution and contrast with less time, effort and invasiveness.
Onnisa Nanegrungsunk +2 more
wiley +1 more source
Phagocytosis of outer segments by retinal pigment epithelium: phagosome-lysosome interaction. [PDF]
, 1993 Elena Bosch, Joseph Horwitz, Dean Bok
openalex +1 more source
The Hsp90β Isoform: An Attractive Target for Drug Development
Medicinal Research Reviews, EarlyView.ABSTRACT The beta isoform of 90 kDa heat shock protein (Hsp90β) plays a critical role in maintaining cellular proteostasis by assisting in the folding and refolding of proteins, which is essential for both normal cellular function and stress response.
Subhabrata Chaudhury +2 more
wiley +1 more source
Metabolic Deregulation of the Blood-Outer Retinal Barrier in Retinitis Pigmentosa
Cell Reports, 2019 Summary: Retinitis pigmentosa (RP) initiates with diminished rod photoreceptor function, causing peripheral and night-time vision loss. However, subsequent loss of cone function and high-resolution daylight and color vision is most debilitating.
Wei Wang +19 more
doaj
Post-traumatic hyperlipofuscinosis in the human retinal pigment epithelium. [PDF]
, 1991 M K Ko +3 more
openalex +1 more source
Assessment of the value of congenital hypertrophy of the retinal pigment epithelium as an ocular marker for familial adenomatous polyposis coli [PDF]
, 1993 Marie Hickey-Dwyer, Colin E. Willoughby
openalex +1 more source