Results 41 to 50 of about 142,219 (404)
Drusenoid retinal pigment epithelium detachments
Revista Brasileira de Oftalmologia, 2015 The authors make a review of drusenoid retinal pigment epithelium detachments(DPDs), a form of retinal pigment epithelium detachment(PED) that evolves from confluent and large soft drusen.Drusenoidretinal pigment epithelial detachments are a recognized ...
Miguel Hage Amaro +5 more
doaj +1 more source
Retinal pigment epithelium changes in Kartagener syndrome
American Journal of Ophthalmology Case Reports, 2018 Purpose: We present the first case in the literature of a patient with Kartagener syndrome and ocular findings of nonexudative age-related macular degeneration. Observations: A 55-year-old woman with Kartagener syndrome and chronic angle closure glaucoma
Maria D. Garcia +4 more
doaj +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2018 Significance Recessive Stargardt macular degeneration (STGD1) and a subset of cone–rod dystrophies are caused by mutations in the Abca4 gene. The ABCA4 protein is a flippase in photoreceptor cells that helps eliminate retinaldehyde, a toxic photoproduct ...
T. Lenis +14 more
semanticscholar +1 more source
Blue light regenerates functional visual pigments in mammals through a retinyl-phospholipid intermediate. [PDF]
, 2017 The light absorbing chromophore in opsin visual pigments is the protonated Schiff base of 11-cis-retinaldehyde (11cRAL). Absorption of a photon isomerizes 11cRAL to all-trans-retinaldehyde (atRAL), briefly activating the pigment before it dissociates ...
Fain, Gordon L +6 more
core +1 more source
Long term evolution of combined hamartoma of the retina and retinal pigment epithelium
Vision Pan-America, 2014 Combined hamartoma of the retina and of the retinal pigment epithelium are extremely rare benign tumors distinguished by retinal pigment epithelium (RPE) and glial tissue proliferation, provoking severe peripapillary and retinal distortion ...
Miriam García Fernández +1 more
doaj +1 more source
Association of drusen deposition with choroidal intercapillary pillars in the aging human eye [PDF]
, 2004 PURPOSE. To determine the pattern of drusen accumulation with age and to investigate the initial sites of deposition and their relationship to choroidal capillaries in human donor eyes from the eye bank of Moorfields Eye Hospital.METHODS.
Al Hosaini, H +5 more
core +1 more source
Mass spectrometry in ocular drug research
Mass Spectrometry Reviews, EarlyView., 2023 Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo +6 more
wiley +1 more source
Foveal simple hamartoma of retinal pigment epithelium
TNOA Journal of Ophthalmic Science and Research, 2018 Congenital anomalies of retinal pigment epithelium (RPE) are rare entities among which simple hamartoma of RPE is extremely rare. Majority of reported cases of congenital simple hamartoma were extrafoveal and patients were asymptomatic. These lesions may
Prabu Baskaran +2 more
doaj +1 more source
Cell Death and Disease, 2018 AimsBlue light is an identified risk factor for age-related macular degeneration (AMD). We investigated oxidative stress markers and mitochondrial changes in A2E-loaded retinal pigment epithelium cells under the blue–green part of the solar spectrum that
M. Marie +10 more
semanticscholar +1 more source
Optical Coherence Tomographic Angiography Imaging in Age-Related Macular Degeneration. [PDF]
, 2017 Optical coherence tomographic angiography (OCTA) is emerging as a rapid, noninvasive imaging modality that can provide detailed structural and flow information on retinal and choroidal vasculature.
Desai, Ria +5 more
core +3 more sources