Results 41 to 50 of about 138,851 (338)

Retinal pigment epithelium changes in Kartagener syndrome

American Journal of Ophthalmology Case Reports, 2018
Purpose: We present the first case in the literature of a patient with Kartagener syndrome and ocular findings of nonexudative age-related macular degeneration. Observations: A 55-year-old woman with Kartagener syndrome and chronic angle closure glaucoma
Maria D. Garcia, Camila V. Ventura, João R. Dias, Ta Chen P. Chang, Audina M. Berrocal   +4 more
doaj   +1 more source

Blue light regenerates functional visual pigments in mammals through a retinyl-phospholipid intermediate. [PDF]

, 2017
The light absorbing chromophore in opsin visual pigments is the protonated Schiff base of 11-cis-retinaldehyde (11cRAL). Absorption of a photon isomerizes 11cRAL to all-trans-retinaldehyde (atRAL), briefly activating the pigment before it dissociates ...
Fain, Gordon L, Hakobyan, Hayk, Ingram, Norianne T, Kaylor, Joanna J, Travis, Gabriel H, Tsan, Avian, Xu, Tongzhou   +6 more
core   +1 more source

Long term evolution of combined hamartoma of the retina and retinal pigment epithelium

Vision Pan-America, 2014
Combined hamartoma of the retina and of the retinal pigment epithelium are extremely rare benign tumors distinguished by retinal pigment epithelium (RPE) and glial tissue proliferation, provoking severe peripapillary and retinal distortion ...
Miriam García Fernández, Joaquín Castro Navarro   +1 more
doaj   +1 more source

Association of drusen deposition with choroidal intercapillary pillars in the aging human eye [PDF]

, 2004
PURPOSE. To determine the pattern of drusen accumulation with age and to investigate the initial sites of deposition and their relationship to choroidal capillaries in human donor eyes from the eye bank of Moorfields Eye Hospital.METHODS.
Al Hosaini, H, Bird, AC, Jeffery, G, Lengyel, I, Luthert, P, Tufail, A   +5 more
core   +1 more source

Dissecting the transcriptome landscape of the human fetal neural retina and retinal pigment epithelium by single-cell RNA-seq analysis

PLoS Biology, 2019
The developmental pathway of the neural retina (NR) and retinal pigment epithelium (RPE) has been revealed by extensive research in mice. However, the molecular mechanisms underlying the development of the human NR and RPE, as well as the interactions ...
Yuqiong Hu, Xiaoye Wang, Boqiang Hu, Yunuo Mao, Yidong Chen, Liying Yan, Jun Yong, Ji Dong, Yuan Wei, Wei Wang, Lu Wen, J. Qiao, Fuchou Tang   +12 more
semanticscholar   +1 more source

Foveal simple hamartoma of retinal pigment epithelium

TNOA Journal of Ophthalmic Science and Research, 2018
Congenital anomalies of retinal pigment epithelium (RPE) are rare entities among which simple hamartoma of RPE is extremely rare. Majority of reported cases of congenital simple hamartoma were extrafoveal and patients were asymptomatic. These lesions may
Prabu Baskaran, Nagesha Chokahalli, Pratyusha Ganne   +2 more
doaj   +1 more source

A Single-Cell Transcriptome Atlas of the Human Retinal Pigment Epithelium

Frontiers in Cell and Developmental Biology, 2021
Human retinal pigment epithelium cells are arranged in a monolayer that plays an important supporting role in the retina. Although the heterogeneity of specific retinal cells has been well studied, the diversity of hRPE cells has not been reported. Here,
Zongren Xu, Zongren Xu, Zongren Xu, Zongren Xu, Xingyun Liao, Xingyun Liao, Xingyun Liao, Xingyun Liao, Na Li, Hongxiu Zhou, Hongxiu Zhou, Hongxiu Zhou, Hong Li, Hong Li, Hong Li, Qi Zhang, Qi Zhang, Qi Zhang, Ke Hu, Ke Hu, Ke Hu, Peizeng Yang, Peizeng Yang, Peizeng Yang, Peizeng Yang, Shengping Hou, Shengping Hou, Shengping Hou, Shengping Hou   +28 more
doaj   +1 more source

Combining hyaluronic acid with chitosan enhances gene delivery [PDF]

, 2014
The low gene transfer efficiency of chitosan-DNA polyplexes is a consequence of their high stability and consequent slow DNA release. The incorporation of an anionic polymer is believed to loosen chitosan interactions with DNA and thus promote higher ...
Bitoque, Diogo, Oliveira, Ana, Silva, Gabriela   +2 more
core   +3 more sources

Impaired ABCA1/ABCG1-mediated lipid efflux in the mouse retinal pigment epithelium (RPE) leads to retinal degeneration

eLife, 2019
Age-related macular degeneration (AMD) is a progressive disease of the retinal pigment epithelium (RPE) and the retina leading to loss of central vision.
F. Storti, Katrin Klee, V. Todorova, Regula Steiner, A. Othman, S. D. van der Velde-Visser, M. Samardzija, I. Meneau, M. Barben, D. Karademir, Valda Pauzuolyte, S. Boye, Frank Blaser, C. Ullmer, J. Dunaief, T. Hornemann, L. Rohrer, A. D. den Hollander, A. von Eckardstein, J. Fingerle, C. Maugeais, C. Grimm   +21 more
semanticscholar   +1 more source

Congenital hypertrophy of retinal pigment epithelium [PDF]

BMJ Case Reports, 2020
A 45-year-old man was referred to the ocular oncology service for evaluation due to a black asymptomatic lesion in his right eye. His medical history included hyperlipidemia and high myopia. On clinical examination, a flat black lesion that looked like a flower was observed ([figure 1A,B][1 ...
Ofira, Zloto, Iris, Moroz, Vicktoria, Vishnevskia-Dai   +2 more
openaire   +2 more sources