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A new mouse model for retinal degeneration due to Fam161a deficiency
FAM161A mutations are the most common cause of inherited retinal degenerations in Israel. We generated a knockout (KO) mouse model, Fam161a tm1b/tm1b , lacking the major exon #3 which was replaced by a construct that include LacZ under the expression of ...
Avigail Beryozkin +7 more
doaj +1 more source
Vitamin A deficiency affects gene expression in the Drosophila melanogaster head
Insufficient dietary intake of vitamin A causes various human diseases. For instance, chronic vitamin A deprivation causes blindness, slow growth, impaired immunity, and an increased risk of mortality in children.
Deepshe Dewett +4 more
doaj +1 more source
Retinal Pigment Epithelium Tear [PDF]
Retinal pigment epithelium tear is a potentially vision threatening complication of retinal pigment epithelial detachment associated with neovascular age-related macular degeneration. Retinal pigment epithelium tear has been reported to occur spontaneously and after treatment with anti-vascular growth endothelial factor agents.
Aleksandra V, Rachitskaya +1 more
openaire +2 more sources
This article is part of a Special Issue entitled: Retinal Proteins - You can teach an old dog new tricks.Cone visual pigments are visual opsins that are present in vertebrate cone photoreceptor cells and act as photoreceptor molecules responsible for ...
Imamoto, Yasushi, Shichida, Yoshinori
core +1 more source
Structure and Conformation of the Carotenoids in Human Retinal Macular Pigment. [PDF]
Human retinal macular pigment (MP) is formed by the carotenoids lutein and zeaxanthin (including the isomer meso-zeaxanthin). MP has several functions in improving visual performance and protecting against the damaging effects of light, and MP levels are
Ana-Andreea Arteni +7 more
doaj +1 more source
Probing how initial retinal configuration controls photochemical dynamics in retinal proteins
The effects of the initial retinal configuration and the active isomerization coordinate on the photochemistry of retinal proteins (RPs) are assessed by comparing photochemical dynamics of two stable retinal ground state configurations (all-trans,15-anti
Sheves M. +6 more
doaj +1 more source
Background: The art of scleral buckle (SB) surgery is being largely forgotten. However, it still remains a good option for selected cases of rhegmatogenous retinal detachment.
Shobhit Varma +4 more
doaj +1 more source
Origin of color tuning in human red, green, and blue cone pigments: SAC-CI and QM/MM study [PDF]
Human color vision is controlled by the red, green, and blue cone pigments. Their photo-absorption wavelengths spread uniquely over the three primary colors, although these pigments include common chromophore, retinal.
Hasegawa, Jun-Ya +2 more
core +1 more source
Early evolution of purple retinal pigments on Earth and implications for exoplanet biosignatures [PDF]
We propose that retinal-based phototrophy arose early in the evolution of life on Earth, profoundly impacting the development of photosynthesis and creating implications for the search for life beyond our planet.
DasSarma, Shiladitya +1 more
core +1 more source
Spectral Tuning Mechanism of Primate Blue-sensitive Visual Pigment Elucidated by FTIR Spectroscopy
Protein-bound water molecules are essential for the structure and function of many membrane proteins, including G-protein-coupled receptors (GPCRs). Our prior work focused on studying the primate green- (MG) and red- (MR) sensitive visual pigments using ...
Kota Katayama +4 more
doaj +1 more source

