Results 31 to 40 of about 8,879 (266)
Spectral Tuning Mechanism of Primate Blue-sensitive Visual Pigment Elucidated by FTIR Spectroscopy
Scientific Reports, 2017 Protein-bound water molecules are essential for the structure and function of many membrane proteins, including G-protein-coupled receptors (GPCRs). Our prior work focused on studying the primate green- (MG) and red- (MR) sensitive visual pigments using ...
Kota Katayama +4 more
doaj +1 more source
Indian Journal of Ophthalmology, 2022 Background: The art of scleral buckle (SB) surgery is being largely forgotten. However, it still remains a good option for selected cases of rhegmatogenous retinal detachment.
Shobhit Varma +4 more
doaj +1 more source
Antioxidants, 2022 Ommochromes are pigments of invertebrates that exhibit oxidative stress protection. The aim of this study was to investigate ommochromes extracted from cephalopod’s skin for their ability to inhibit age-related-macular degeneration (AMD)-related factors ...
Luján Lidianys María Lewis +11 more
doaj +1 more source
Spectral tuning and deactivation kinetics of marine mammal melanopsins.
PLoS ONE, 2021 In mammals, the photopigment melanopsin (Opn4) is found in a subset of retinal ganglion cells that serve light detection for circadian photoentrainment and pupil constriction (i.e., mydriasis).
Jeffry I Fasick +6 more
doaj +3 more sources
A novel source of methylglyoxal and glyoxal in retina: implications for age-related macular degeneration. [PDF]
PLoS ONE, 2012 Aging of retinal pigment epithelial (RPE) cells of the eye is marked by accumulations of bisretinoid fluorophores; two of the compounds within this lipofuscin mixture are A2E and all-trans-retinal dimer.
Kee Dong Yoon +4 more
doaj +1 more source
Retinitis Pigmentosa with Congenital Sensorineural Hearing Loss: Ushers Syndrome
BLDE University Journal of Health Sciences, 2020 Background: Retinitis pigmentosa or pigmentary retinal dystrophy denotes a clinically and genetically diverse group of inherited diffuse retinal degenerative diseases.
M H Patil, Piyushi Sao
doaj +1 more source
Deep Learning-Based Detection of Pigment Signs for Analysis and Diagnosis of Retinitis Pigmentosa
Sensors, 2020 Ophthalmological analysis plays a vital role in the diagnosis of various eye diseases, such as glaucoma, retinitis pigmentosa (RP), and diabetic and hypertensive retinopathy.
Muhammad Arsalan +4 more
doaj +1 more source
RETINAL SPARING BY SELECTIVE RETINAL PIGMENT EPITHELIAL PHOTOCOAGULATION [PDF]
Evidence-Based Eye Care, 1999 To investigate whether photocoagulation of the retinal pigment epithelium is possible with sparing of the photoreceptors.Mild laser effects of a neodymium:yttrium-lithium-fluoride (Nd:YLF) laser (527 nm) were applied to 17 patients. To establish the necessary energy, test exposures were performed to the lower macula (laser variables: 1.7 microseconds ...
J, Roider +4 more
openaire +2 more sources
CryoEM structure and small-angle X-ray scattering analyses of porcine retinol-binding protein 3
Open BiologyThe vertebrate visual cycle hinges on enzymatically converting all-trans-retinol (at-ROL) into 11-cis-retinal (11c-RAL), the chromophore that binds to opsins in photoreceptors, forming light-responsive pigments.
Vineeta Kaushik +7 more
doaj +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source