Results 41 to 50 of about 33,802 (359)

Deep Learning-Based Detection of Pigment Signs for Analysis and Diagnosis of Retinitis Pigmentosa

Sensors, 2020
Ophthalmological analysis plays a vital role in the diagnosis of various eye diseases, such as glaucoma, retinitis pigmentosa (RP), and diabetic and hypertensive retinopathy.
Muhammad Arsalan, Na Rae Baek, Muhammad Owais, Tahir Mahmood, Kang Ryoung Park   +4 more
doaj   +1 more source

Challenges in Age-Related Macular Degeneration: From Risk Factors to Novel Diagnostics and Prevention Strategies

Frontiers in Medicine, 2022
Age-related macular degeneration (AMD) is a chronic multifactorial eye disease representing the primary cause of vision loss in people aged 60 years and older.
Marco Lombardo, Marco Lombardo, Sebastiano Serrao, Sebastiano Serrao, Giuseppe Lombardo, Giuseppe Lombardo   +5 more
doaj   +1 more source

Sex-related differences in chromatic sensitivity [PDF]

, 2008
Generally women are believed to be more discriminating than men in the use of colour names and this is often taken to imply superior colour vision. However, if both X-chromosome linked colour deficient males (~8%) and females (
J.A. HARLOW, J.L. BARBUR, L.T. SHARPE, Levine, M. RODRÍGUEZ-CARMONA, Rodriguez-Carmona, Rodriguez-Carmona, Sharpe   +7 more
core   +1 more source

Infrared spectroscopy of phytochrome and model pigments [PDF]

, 1990
Fourier-transform infrared difference spectra between the red-absorbing and far-red-absorbing forms of oat phytochrome have been measured in H2O and 2H2O. The difference spectra are compared with infrared spectra of model compounds, i.e. the (5Z,10Z,15Z)-
Bagley K., Bagley K. A., Braiman M. S., Braslavsky S. E., Brock H., Cavaleiro J. A. S., Chai Y.-G., Eilfeld P., Engelhard M., Falk H., Farrens D. L., Fodor S. P. A., Furuya M., Ganter U. M., Grimm R., Grombein S., Holt R. E., Hsieh Y.-Z., Kendrick R. E., Kufer W., Lagarias J. C., Lagarias J. C., Lagarias J. C., Margulies L., Margulies L., Margulies L., Mathies R. A., Moon D.-K., Oseroff A. R., Rospendowski B. N., Rothschild K. J., Rudiger W., Sarkar H. K., Sawatzki J., Scheer H., Scheer H., Schendel R., Schirmer T., Schneider S., Shropshire W., Siebert F., Siebert F., Siebert F., Sulkes M., Szalontai B., Thummler F.   +45 more
core   +1 more source

A novel source of methylglyoxal and glyoxal in retina: implications for age-related macular degeneration. [PDF]

PLoS ONE, 2012
Aging of retinal pigment epithelial (RPE) cells of the eye is marked by accumulations of bisretinoid fluorophores; two of the compounds within this lipofuscin mixture are A2E and all-trans-retinal dimer.
Kee Dong Yoon, Kazunori Yamamoto, Keiko Ueda, Jilin Zhou, Janet R Sparrow   +4 more
doaj   +1 more source

Retinal pigment epithelial cell proliferation [PDF]

Experimental Biology and Medicine, 2015
The human retinal pigment epithelium forms early in development and subsequently remains dormant, undergoing minimal proliferation throughout normal life. Retinal pigment epithelium proliferation, however, can be activated in disease states or by removing retinal pigment epithelial cells into culture.
Jeffrey, Stern, Sally, Temple
openaire   +2 more sources

CryoEM structure and small-angle X-ray scattering analyses of porcine retinol-binding protein 3

Open Biology
The vertebrate visual cycle hinges on enzymatically converting all-trans-retinol (at-ROL) into 11-cis-retinal (11c-RAL), the chromophore that binds to opsins in photoreceptors, forming light-responsive pigments.
Vineeta Kaushik, Luca Gessa, Nelam Kumar, Matyáš Pinkas, Mariusz Czarnocki-Cieciura, Krzysztof Palczewski, Jiří Nováček, Humberto Fernandes   +7 more
doaj   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Drosophila melanogaster rhodopsin Rh7 is a UV-to-visible light sensor with an extraordinarily broad absorption spectrum

Scientific Reports, 2017
The genome of Drosophila melanogaster contains seven rhodopsin genes. Rh1-6 proteins are known to have respective absorption spectra and function as visual pigments in ocelli and compound eyes.
Kazumi Sakai, Kei Tsutsui, Takahiro Yamashita, Naoyuki Iwabe, Keisuke Takahashi, Akimori Wada, Yoshinori Shichida   +6 more
doaj   +1 more source

Non-viral delivery and optimized optogenetic stimulation of retinal ganglion cells led to behavioral restoration of vision [PDF]

, 2012
Stimulation of retinal neurons using optogenetics via use of chanelrhodopsin-2 (ChR2) has opened up a new direction for restoration of vision for treatment of retinitis pigmentosa (RP).
Edward Wong, Ling Gu, Mathew Ficinski, Samarendra Mohanty, Samarendra Mohanty, Shivaranjani Shivalingaiah   +5 more
core   +2 more sources