Results 61 to 70 of about 5,449,684 (261)
The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
PLoS ONEHow tissue-specific progenitor cells generate adult tissues is a puzzle in organogenesis. Using single-cell RNA sequencing of control and Six3 and Six6 compound-mutant mouse embryonic eyecups, we demonstrated that these two closely related transcription ...
Alexander Ferrena +4 more
doaj +1 more source
Co-ordinating retinal histogenesis: early cell cycle exit enhances early cell fate determination in the Xenopus retina [PDF]
, 2002 The laminar arrays of distinct cell types in the vertebrate retina are built by a histogenic process in which cell fate is correlated with birth order.
Philpott, A. +4 more
core
Milieu-adopted in vitro and in vivo differentiation of mesenchymal tissues derived from different adult human CD34-negative progenitor cell clones [PDF]
, 2005 Adult mesenchymal stem cells with multilineage differentiation potentially exist in the bone marrow, but have also been isolated from the peripheral blood.
Moser, C. +4 more
core +1 more source
Thioredoxin‐2 Alleviates Osteoporosis by Restraining FOXO3a Nuclear Translocation
Advanced Science, EarlyView.Endothelial TRX2 preserves bone homeostasis by retaining FOXO3a at mitochondria and limiting TRAIL production. Loss of TRX2 or oxidative stress releases FOXO3a for nuclear translocation, increasing endothelial TRAIL secretion and driving osteoclast formation and bone loss.
Chi Zhan +10 more
wiley +1 more source
Pilot trial on determinants of progenitor cell recruitment to the infarcted human myocardium [PDF]
, 2008 Background— Clinical trials indicate a beneficial effect of intracoronary infusion of progenitor cells on myocardial function in patients with ischemic heart disease.
Dimmeler, S +11 more
core
Advanced Intelligent Systems, EarlyView.This review highlights recent advances in automated iPSC culture systems integrating robotics, advanced imaging, artificial intelligence, and process control. These technologies improve reproducibility, scalability, and quality in cell expansion, differentiation, and real‐time monitoring, while emerging AI‐enabled and closed‐loop approaches offer new ...
Hyoryong Lee +3 more
wiley +1 more source
Notch Signaling Activation Enhances Human Adipose-Derived Stem Cell Retinal Differentiation
Stem Cells International, 2018 Retinal disease treatment by stem cell-based replacement relies on stem cell differentiation into retinal cells. We previously demonstrated that human periodontal ligament-derived stem cells can be directed into retinal lineage upon induction.
Yuqiang Huang +6 more
doaj +1 more source
Influence of microglia on retinal progenitor cell turnover and cell replacement [PDF]
Eye, 2008 Microglia within the retina are continually replaced from the bone marrow and are the resident myeloid-derived cells within the retina. Throughout life, microglial function is conditioned by the microenvironment affording immunomodulation to control inflammation as well as functioning to enable normal development and, during adulthood, maintain normal ...
openaire +2 more sources
Distribution of doublecortin in the developing retina of birds: A comparative analysis
The Anatomical Record, EarlyView.Abstract The avian retina presents an elegant and highly accessible model for investigating the spatial and temporal dynamics of neurogenesis within the central nervous system. In recent years, the microtubule cytoskeleton has emerged not merely as a structural scaffold, but as a dynamic regulator of the transition of a morphologically homogeneous pool
Javier Francisco‐Morcillo +5 more
wiley +1 more source