Results 41 to 50 of about 24,391 (241)

Characterization of Progenitor Cells during Canine Retinal Development [PDF]

Stem Cells International, 2012
We identify the presence of progenitor cells during retinal development in the dog, as this species represents a natural model for studying several breed-specific degenerative retinal disorders. Antibodies to detected progenitor cells (Pax6, C-kit, and nestin) and ganglion cells (BDNF, Brn3a, and Thy1) were used in combination with H3 for the purpose ...
Mallely Ávila-García, Gustavo García-Sánchez, Esmeralda Lira-Romero, Norma Moreno-Mendoza   +3 more
openaire   +3 more sources

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

Mesenchymal stem cell–derived small extracellular vesicles enhance the therapeutic effect of retinal progenitor cells in retinal degenerative disease rats

Neural Regeneration Research
Our previous study demonstrated that combined transplantation of bone marrow mesenchymal stem cells and retinal progenitor cells in rats has therapeutic effects on retinal degeneration that are superior to transplantation of retinal progenitor cells ...
Chunge Ren, Min Chen, Bangqi Ren, Yuxiao Zeng, Qiang Tan, Qiyou Li, Xue Zhang, Yajie Fang, Yixiao Zhou, Weitao Zhang, Fang Chen, Baishijiao Bian, Yong Liu   +12 more
doaj   +1 more source

Mesenchymal Stem Cells: Signaling Pathways in Transdifferentiation Into Retinal Progenitor Cells

Basic and Clinical Neuroscience, 2021
Several signaling pathways and transcription factors control the cell fate in its in vitro development and differentiation. The orchestrated use of these factors results in cell specification. In coculture methods, many of these factors secrete from host
Hamid Aboutaleb Kadkhodaeian
doaj  

Activation of c-Jun N-terminal kinase (JNK) during mitosis in retinal progenitor cells. [PDF]

PLoS ONE, 2012
Most studies of c-Jun N-terminal Kinase (JNK) activation in retinal tissue were done in the context of neurodegeneration. In this study, we investigated the behavior of JNK during mitosis of progenitor cells in the retina of newborn rats.
Vinicius Toledo Ribas, Bruno Souza Gonçalves, Rafael Linden, Luciana Barreto Chiarini   +3 more
doaj   +1 more source

Gap junctions modulate interkinetic nuclear movement in retinal progenitor cells

, 2005
During early retinal development, progenitor cells must divide repeatedly to expand the progenitor pool. During G1 and G2 of the cell cycle, progenitor cell nuclei migrate back-and-forth across the proliferative zone in a process termed interkinetic ...
Lüneborg, N.L., Mobbs, Peter, Becker, D.L., Becker, David L., Pearson, R.A., Mobbs, P., Pearson, Rachael A.; id_orcid, Lüneborg, Nanna L.   +7 more
core   +1 more source

Cultured subventricular zone progenitor cells transduced with neurogenin-2 become mature glutamatergic neurons and integrate into the dentate gyrus. [PDF]

, 2012
We have previously shown that transplantation of immature DCX+/NeuN+/Prox1+ neurons (found in the neonatal DG), but not undifferentiated neuronal progenitor cells (NPCs) from ventral subventricular zone (SVZ), results in neuronal maturation in vivo ...
Xia Chen, Lepier Alexandra, Tolkovsky Aviva M., Alexandra Lepier, Chen, Xia, Aviva M Tolkovsky, Lepier, Alexandra, Chen, X., Berninger, Benedikt, Herbert, Joe, Chen Xia, Herbert Joe, Lepier, A., Tolkovsky, A.M., Berninger Benedikt, Tolkovsky, Aviva M., Benedikt Berninger, Joe Herbert, Berninger, B., Herbert, J.   +19 more
core   +1 more source

Retinal progenitor cells (jCell) for retinitis pigmentosa

Frontiers in Cellular Neuroscience
ObjectiveTo assess the safety and tolerability of intravitreal injection of human retinal progenitor cells (RPCs) at multiple dose levels in adults with non-syndromic retinitis pigmentosa (RP).DesignA prospective, multicenter, open-label, single-arm, Phase I/IIa safety study of RPCs in adults with RP (n = 28). Two patient cohorts were studied: Cohort 1:
Yang, Jing, Kuppermann, Baruch D, Liao, David, Mehta, Mitul C, Hsiang, Chinhui, Menges, Steven, Boyer, David S, Klassen, Henry   +7 more
openaire   +3 more sources

Electrospun PGS/PCL, PLLA/PCL, PLGA/PCL and pure PCL scaffolds for retinal progenitor cell cultivation

, 2020
Recent advances in cell transplantation technologies have shown that polymeric fibrous tissue-engineered scaffolds provide a suitable physical environment, including the structural support, for cell delivery and effectively mimic the transplanted cells ...
Masaeli, Elahe, Karamali, Fereshteh, Behtaj, Sanaz, G. Anissimov, Yuri, Rybachuk, Maksym   +4 more
core   +1 more source

Polo-Like Kinase 3 Appears Dispensable for Normal Retinal Development Despite Robust Embryonic Expression. [PDF]

PLoS ONE, 2016
During retinogenesis seven different cell types are generated in distinct yet overlapping timepoints from a population of retinal progenitor cells.
Jillian J Goetz, Lauren A Laboissonniere, Andrea K Wester, Madison R Lynch, Jeffrey M Trimarchi   +4 more
doaj   +1 more source