Results 21 to 30 of about 5,449,684 (261)

SURGICAL RETINAL EXPLANTS AS A SOURCE OF RETINAL PROGENITOR CELLS

Retina, 2021
Purpose: To describe the novel observation of spontaneously migrating retinal cells from living donor surgical retinal explants that express progenitor cell markers in the absence of exogenous growth factors. Methods: Surgical retinal explants were harvested from 5 consecutive ...
Too, Lay Khoon, Shen, Weiyong, Mammo, Zaid, Osaadon, Perach, Gillies, Mark C., Simunovic, Matthew P.   +5 more
openaire   +3 more sources

Physiological Postnatal Neurogenesis, Development, and Maturation in the Regenerable Retina [PDF]

J Comp Neurol
Retinal structural remodeling from hatchlings to preadults in axolotls involves neurogenesis, cell redistribution, increased expression of photopsins and connexins, and enhanced inhibitory regulation. The peripheral retina of young animals possesses more columnar undifferentiated cells, resembling the columnar DCX‐positive progenitor cells in the ...
Pang V, Zhong W, Yang Z, Wu S, Pang J.
europepmc   +2 more sources

Morphological asymmetry in dividing retinal progenitor cells [PDF]

Development, Growth & Differentiation, 2003
For the understanding of histogenetic events in the 3‐D retinal neuroepithelium, direct observation of the progenitor cells and their morphological changes is required. A slice culture method has been developed by which the behavior of single progenitor cells can be monitored.
Kanako, Saito, Ayano, Kawaguchi, Saori, Kashiwagi, Sadao, Yasugi, Masaharu, Ogawa, Takaki, Miyata   +5 more
openaire   +2 more sources

A microfabricated scaffold for retinal progenitor cell grafting [PDF]

Biomaterials, 2008
Diseases that cause photoreceptor cell degeneration afflict millions of people, yet no restorative treatment exists for these blinding disorders. Replacement of photoreceptors using retinal progenitor cells (RPCs) represents a promising therapy for the treatment of retinal degeneration.
William L, Neeley, Stephen, Redenti, Henry, Klassen, Sarah, Tao, Tejal, Desai, Michael J, Young, Robert, Langer   +6 more
openaire   +2 more sources

Dual requirement for Pax6 in retinal progenitor cells [PDF]

Development, 2008
Throughout the developing central nervous system, pre-patterning of the ventricular zone into discrete neural progenitor domains is one of the predominant strategies used to produce neuronal diversity in a spatially coordinated manner. In the retina, neurogenesis proceeds in an intricate chronological and spatial sequence, yet it remains unclear ...
Oron-Karni, Varda, Farhy, Chen, Elgart, Michael, Marquardt, Till, Remizova, Lena, Yaron, Orly, Xie, Qing, Cvekl, Ales, Ashery-Padan, Ruth   +8 more
openaire   +3 more sources

Intravitreal Injection of Human Retinal Progenitor Cells for Treatment of Retinal Degeneration [PDF]

Medical Science Monitor, 2020
BACKGROUND Retinal degeneration causes irreversible blindness. Human retinal progenitor cells (hRPCs) have the potential to treat retinal diseases. The vitreous cavity is a relatively immune-privileged site that is suitable for stem cell transplantation in the treatment of retinal diseases.
Wang, Zhuoshi, Gao, Fei, Zhang, Mingqi, Zheng, Yuqiang, Zhang, Fenglei, Xu, Ling, Cao, Liu, He, Wei   +7 more
openaire   +2 more sources

Gap junctions modulate interkinetic nuclear movement in retinal progenitor cells [PDF]

, 2005
During early retinal development, progenitor cells must divide repeatedly to expand the progenitor pool. During G1 and G2 of the cell cycle, progenitor cell nuclei migrate back-and-forth across the proliferative zone in a process termed interkinetic ...
Lüneborg, N.L., Mobbs, Peter, Becker, D.L., Becker, David L., Pearson, R.A., Mobbs, P., Pearson, Rachael A.; id_orcid, Lüneborg, Nanna L.   +7 more
core   +1 more source

Stabilization of the retinal vascular network by reciprocal feedback between blood vessels and astrocytes [PDF]

, 2005
Development of the retinal vasculature is controlled by a hierarchy of interactions among retinal neurons, astrocytes and blood vessels. Retinal neurons release platelet-derived growth factor (PDGFA) to stimulate proliferation of astrocytes, which in ...
Heloise West, Richardson, WD, West, H, William D. Richardson, Fruttiger, M, Marcus Fruttiger   +5 more
core   +1 more source

Purinergic and muscarinic modulation of the cell cycle and calcium signaling in the chick retinal ventricular zone [PDF]

, 2002
Spontaneous calcium transients occur in the ventricular zone of the chick retina and result from the endogenous release of neurotransmitters in the absence of action potentials.
Catsicas, M., Peter Mobbs, Pearson, R., Pearson, Rachel; id_orcid, Becker, D., Pearson, R, Rachel Pearson, Becker, D, Mobbs, P, Becker, David, Marina Catsicas, Catsicas, Marina, Catsicas, M, Mobbs, Peter, David Becker, Mobbs, P.   +15 more
core   +1 more source

Profound Re-Organization of Cell Surface Proteome in Equine Retinal Pigment Epithelial Cells in Response to In Vitro Culturing [PDF]

, 2012
The purpose of this study was to characterize the cell surface proteome of native compared to cultured equine retinal pigment epithelium (RPE) cells. The RPE plays an essential role in visual function and represents the outer blood-retinal barrier.
Kerstin N. Euler, Ueffing, Marius, Fröhlich, K.J.H., Stefanie Hauck, Marius Ueffing, Euler, K.N., Fröhlich, Kristina J. H., Kerstin Euler, Claudia Alge-priglinger, Stefanie M. Hauck, Deeg, Cornelia A., Hauck, Stefanie M., Kristina J. H. Fröhlich, Euler, Kerstin N., Cornelia A. Deeg, Christoph Szober, Szober, Christoph M., Hauck, S.M., Ueffing, M., Kristina Fröhlich, Cornelia Deeg, Christoph M. Szober, Szober, C.M., Alge-Priglinger, C.S., Alge-Priglinger, Claudia, Deeg, C.A.   +25 more
core   +1 more source