Results 11 to 20 of about 24,391 (241)

Cell Fate of Retinal Progenitor Cells: In Ovo UbC-StarTrack Analysis [PDF]

International Journal of Molecular Sciences, 2022
Clonal cell analysis outlines the ontogenic potential of single progenitor cells, allowing the elucidation of the neural heterogeneity among different cell types and their lineages.
Scicolone, Gabriel Edgardo, Olmos-Carreño, Cindy L., López-Mascaraque, Laura, Cindy L. Olmos-Carreño, Scicolone, Gabriel E., Figueres-Oñate, María, Gabriel E. Scicolone, María Figueres-Oñate, Laura López-Mascaraque, Olmos Carreño, Cindy Lorena, Figueres Oñate, María, López Mascaraque, Laura   +11 more
core   +5 more sources

Activated adult microglia influence retinal progenitor cell proliferation and differentiation toward recoverin-expressing neuron-like cells in a co-culture model

Graefe's Archive for Clinical and Experimental Ophthalmology, 2015
PURPOSE: Microglia contribute to immune homeostasis of the retina, and thus act as a potential regulator determining successful repair or retinal stem cell transplantation.
David A Copland, Andrew D Dick, Copland David A   +2 more
exaly   +2 more sources

Sumoylation controls retinal progenitor proliferation by repressing cell cycle exit in Xenopus laevis

Developmental Biology, 2010
Precisely controlled progenitor proliferation is essential for normal development. However, molecular mechanisms, which control the correct timing of cell cycle withdrawal during development, have been poorly understood.
Koji Terada, Takahisa Furukawa
exaly   +2 more sources

Jarid2 promotes temporal progression of retinal progenitors via repression of Foxp1

Cell Reports, 2023
Summary: Transitions in competence underlie the ability of CNS progenitors to generate a diversity of neurons and glia. Retinal progenitor cells in mouse generate early-born cell types embryonically and late-born cell types largely postnatally.
Jianmin Zhang, Jacqueline M. Roberts, Fei Chang, Joon Schwakopf, Monica L. Vetter   +4 more
doaj   +1 more source

SURGICAL RETINAL EXPLANTS AS A SOURCE OF RETINAL PROGENITOR CELLS

Retina, 2021
Purpose: To describe the novel observation of spontaneously migrating retinal cells from living donor surgical retinal explants that express progenitor cell markers in the absence of exogenous growth factors. Methods: Surgical retinal explants were harvested from 5 consecutive ...
Too, Lay Khoon, Shen, Weiyong, Mammo, Zaid, Osaadon, Perach, Gillies, Mark C., Simunovic, Matthew P.   +5 more
openaire   +3 more sources

Novel Technique for Retinal Nerve Cell Regeneration with Electrophysiological Functions Using Human Iris-Derived iPS Cells

Cells, 2021
Regenerative medicine in ophthalmology that uses induced pluripotent stem cells (iPS) cells has been described, but those studies used iPS cells derived from fibroblasts.
Naoki Yamamoto, Noriko Hiramatsu, Mahito Ohkuma, Natsuko Hatsusaka, Shun Takeda, Noriaki Nagai, Ei-ichi Miyachi, Masashi Kondo, Kazuyoshi Imaizumi, Masayuki Horiguchi, Eri Kubo, Hiroshi Sasaki   +11 more
doaj   +1 more source

Morphological asymmetry in dividing retinal progenitor cells [PDF]

Development, Growth & Differentiation, 2003
For the understanding of histogenetic events in the 3‐D retinal neuroepithelium, direct observation of the progenitor cells and their morphological changes is required. A slice culture method has been developed by which the behavior of single progenitor cells can be monitored.
Kanako, Saito, Ayano, Kawaguchi, Saori, Kashiwagi, Sadao, Yasugi, Masaharu, Ogawa, Takaki, Miyata   +5 more
openaire   +2 more sources

Intravitreal Injection of Human Retinal Progenitor Cells for Treatment of Retinal Degeneration [PDF]

Medical Science Monitor, 2020
BACKGROUND Retinal degeneration causes irreversible blindness. Human retinal progenitor cells (hRPCs) have the potential to treat retinal diseases. The vitreous cavity is a relatively immune-privileged site that is suitable for stem cell transplantation in the treatment of retinal diseases.
Wang, Zhuoshi, Gao, Fei, Zhang, Mingqi, Zheng, Yuqiang, Zhang, Fenglei, Xu, Ling, Cao, Liu, He, Wei   +7 more
openaire   +2 more sources

Dual requirement for Pax6 in retinal progenitor cells [PDF]

Development, 2008
Throughout the developing central nervous system, pre-patterning of the ventricular zone into discrete neural progenitor domains is one of the predominant strategies used to produce neuronal diversity in a spatially coordinated manner. In the retina, neurogenesis proceeds in an intricate chronological and spatial sequence, yet it remains unclear ...
Oron-Karni, Varda, Farhy, Chen, Elgart, Michael, Marquardt, Till, Remizova, Lena, Yaron, Orly, Xie, Qing, Cvekl, Ales, Ashery-Padan, Ruth   +8 more
openaire   +3 more sources

Single-cell RNA sequencing unravels the transcriptional network underlying zebrafish retina regeneration

eLife, 2023
In the lesioned zebrafish retina, Müller glia produce multipotent retinal progenitors that generate all retinal neurons, replacing lost cell types. To study the molecular mechanisms linking Müller glia reactivity to progenitor production and neuronal ...
Laura Celotto, Fabian Rost, Anja Machate, Juliane Bläsche, Andreas Dahl, Anke Weber, Stefan Hans, Michael Brand   +7 more
doaj   +1 more source