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Journal of Education, Health and Sport, 2018 Budny Agnieszka, Grochowski Cezary. Retinoblastoma. Journal of Education, Health and Sport. 2018;8(7):204-213. eISNN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.1299573 http://ojs.ukw.edu.pl/index.php/johs/article/view/5611 https://pbn.nauka.gov.pl/sedno-webapp/works/868825 The journal has had 7 points in Ministry of Science and ...
Agnieszka Budny, Cezary Grochowski
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Retinoblastoma from human stem cell-derived retinal organoids
Nature Communications, 2021 Retinoblastoma is a childhood cancer of the developing retina that initiates with biallelic inactivation of the RB1 gene. Children with germline mutations in RB1 have a high likelihood of developing retinoblastoma and other malignancies later in life ...
Jackie L. Norrie +18 more
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Multi-Functionalized Nanomaterials and Nanoparticles for Diagnosis and Treatment of Retinoblastoma
Biosensors, 2021 Retinoblastoma is a rare type of cancer, and its treatment, as well as diagnosis, is challenging, owing to mutations in the tumor-suppressor genes and lack of targeted, efficient, cost-effective therapy, exhibiting a significant need for novel approaches
R. Arshad +6 more
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Orphanet Journal of Rare Diseases, 2006 Retinoblastoma is a rare eye tumor of childhood that arises in the retina. It is the most common intraocular malignancy of infancy and childhood; with an incidence of 1/15,000-20,000 live births. The two most frequent symptoms revealing retinoblastoma are leukocoria and strabismus.
Laurence Desjardins +5 more
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Global Retinoblastoma Presentation and Analysis by National Income Level
JAMA Oncology, 2020 This cross-sectional analysis reports the retinoblastoma stage at diagnosis across the world during a single year, investigates associations between clinical variables and national income level, and investigates risk factors for advanced disease at ...
semanticscholar +1 more source
Modern treatment of retinoblastoma: A 2020 review
Indian Journal of Ophthalmology, 2020 Retinoblastoma management remains complex, requiring individualized treatment based on International Classification of Retinoblastoma (ICRB) staging, germline mutation status, family psychosocial factors and cultural beliefs, and available institutional ...
D. Ancona-Lezama, L. Dalvin, C. Shields
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The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit. [PDF]
Genes & Development, 1993 The retinoblastoma protein (p110RB) interacts with many cellular proteins in complexes potentially important for its growth-suppressing function. We have developed and used an improved version of the yeast two-hybrid system to isolate human cDNAs ...
T. Durfee +7 more
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The Lancet, 2012 Retinoblastoma is an aggressive eye cancer of infancy and childhood. Survival and the chance of saving vision depend on severity of disease at presentation. Retinoblastoma was the first tumour to draw attention to the genetic aetiology of cancer. Despite good understanding of its aetiology, mortality from retinoblastoma is about 70% in countries of low
Gallie Brenda L. +6 more
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Retinoblastoma: Etiology, Modeling, and Treatment
Cancers, 2020 Retinoblastoma is a retinal cancer that is initiated in response to biallelic loss of RB1 in almost all cases, together with other genetic/epigenetic changes culminating in the development of cancer. RB1 deficiency makes the retinoblastoma cell-of-origin
R. Kaewkhaw, Duangnate Rojanaporn
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Retinoblastoma and vision [PDF]
Eye, 2022 AbstractThe assessment of vision has a growing importance in the management of retinoblastoma in the era of globe-conserving therapy, both prior to and after treatment. As survival rates approach 98–99% and globe salvage rates reach ever-higher levels, it is important to provide families with information regarding the visual outcomes of different ...
Omar Warda +4 more
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