Results 21 to 30 of about 68,477 (247)

Expression of MMP-14 and CD44 associated with proliferation of retinoblastoma cells

Medicine Science, 2019
Retinoblastoma is a the most common primary intraocular malignant tumor in childhood. The eexpressions of CD44 and MMP-14 and Their role in proliferation and migration cells appear crucial for retinoblastoma invasion.
Hendrian D. Soebagjo, Evelyn Komaratih, Susy Fatmariyanti, Nurwasis Nurwasis, Aulanniam Aulanniam   +4 more
doaj   +1 more source

Retinoblastoma genetics in India: From research to implementation

Indian Journal of Ophthalmology, 2015
Retinoblastoma is the prototypic genetic cancer. India carries the biggest burden of retinoblastoma globally, with an estimated 1500 new cases annually.
Helen Dimaras
doaj   +1 more source

A rare case of adult onset retinoblastoma

Oman Journal of Ophthalmology, 2011
Retinoblastoma usually manifests before five years of age. Retinoblastoma in an adult is extremely rare. Twenty-three cases of retinoblastoma in adults 20 years or older have been reported in world literature.
Sunil Kumar Singh, Dipankar Das, Harsha Bhattacharjee, Jyotirmay Biswas, Ganesh Kuri, Kasturi Bhattacharjee, Hemlata Deka, Akshay Chandra Deka   +7 more
doaj   +1 more source

Nitric oxide suppression by secreted frizzled-related protein 2 drives retinoblastoma

Cell Reports, 2023
Summary: Retinoblastoma is a cancer of the infant retina primarily driven by loss of the Rb tumor suppressor gene, which is undruggable. Here, we report an autocrine signaling, mediated by secreted frizzled-related protein 2 (SFRP2), which suppresses ...
Panneerselvam Jayabal, Fuchun Zhou, Xiuye Ma, Kathryn M. Bondra, Barron Blackman, Susan T. Weintraub, Yidong Chen, Patricia Chévez-Barrios, Peter J. Houghton, Brenda Gallie, Yuzuru Shiio   +10 more
doaj   +1 more source

Retinoblastoma: A spectrum of manifestations in three cases on B-scan

Indian Journal of Radiology and Imaging, 2007
Retinoblastoma is a primary intraocular neoplasm of childhood, presenting with leukocoria.We present a spectrum of three cases. First two cases are of bilateral retinoblastoma and last case is a retinoblastoma of right eye.
V. D. Aironi, Sonesh Chougule, Suneet Khetarpal, Gopalsingh Bhati   +3 more
doaj   +1 more source

Retinoblastoma in Calabar Nigeria: An 18-Month Retrospective Review of Clinical Presentation at a Tertiary Eye Center

Nigerian Journal of Medicine, 2022
Background: Retinoblastoma, although rare, is the most frequently occurring primary intraocular tumor of childhood. While a cure is often achieved where appropriate treatment is instituted early in the disease, late presentation often leads to ...
Elizabeth Dennis Nkanga, Iwassam Elemi Agbor, Sunday Nnamdi Okonkwo, Ido Didi Fabian, Ekpereonne Babatunde Esu, Dennis George Nkanga, Friday Akwagiobe Odey, Jacintha Banku Okoi-Obuli   +7 more
doaj   +1 more source

Inhibitory activity of bevacizumab to differentiation of retinoblastoma cells. [PDF]

PLoS ONE, 2012
Vascular endothelial growth factor (VEGF) is a major regulator in retinal and choroidal angiogenesis, which are common causes of blindness in all age groups.
Jang Won Heo, Jin Hyoung Kim, Chang Sik Cho, Hyoung Oh Jun, Dong Hun Kim, Young Suk Yu, Jeong Hun Kim   +6 more
doaj   +1 more source

Adjuvant therapy for children treated by enucleation at diagnosis of retinoblastoma

EJC Paediatric Oncology, 2023
Introduction: Advanced localized retinoblastoma can be cured by enucleation, but extraocular spread of retinoblastoma cells is associated with a high mortality.
Yelena Diarra, Christina Brockmeyer, Karen Fischhuber, Isabel Hülsenbeck, Saskia Ting, Madlen Reschke, Tobias Kiefer, Anna Hannbücken, Maren Wagemanns, Leyla Jabbarli, Selma Sirin, Regina Wieland, Gudrun Fleischhack, Johannes H. Schulte, Martin Ebinger, Dietmar Lohmann, Bert Müller, Daniela Süsskind, Christoph Schwab, Ines Brecht, Angelika Eggert, Stefan Schönberger, Petra Ritter-Sovinz, Nikolaos Bechrakis, Sophia Göricke, Beate Timmermann, Eva Biewald, Petra Ketteler   +27 more
doaj   +1 more source

Differentiating MYCN-amplified RB1 wild-type retinoblastoma from biallelic RB1 mutant retinoblastoma using MR-based radiomics: a retrospective multicenter case–control study

Scientific Reports
MYCN-amplified RB1 wild-type (MYCN amp RB1 +/+) retinoblastoma is a rare and aggressive subtype, often resistant to standard therapies. Identifying unique MRI features is crucial for diagnosing this subtype, as biopsy is not recommended. This study aimed
Christiaan M. de Bloeme , Robin W. Jansen, Liesbeth Cardoen, Sophia Göricke, Sabien van Elst, Jaime Lyn Jessen, Aparna Ramasubramanian, Alison H. Skalet, Audra K. Miller, Philippe Maeder, Ogul E. Uner, G. Baker Hubbard, Hans Grossniklaus, H. Culver Boldt, Kim E. Nichols, Rachel C. Brennan, Saugata Sen, Mériam Koob, Selma Sirin, Hervé J. Brisse, Paolo Galluzzi, Charlotte J. Dommering, Matthijs Cysouw, Ronald Boellaard, Josephine C. Dorsman, Annette C. Moll, Marcus C. de Jong, Pim de Graaf, European Retinoblastoma Imaging Collaboration   +28 more
doaj   +1 more source

Current therapy and recent advances in the management of retinoblastoma

Indian Journal of Medical and Paediatric Oncology, 2012
Retinoblastoma is the most common intraocular malignancy in children. The survival of retinoblastoma patients and visual outcome has improved dramatically in the developed world.
Rachna Meel, Venkatraman Radhakrishnan, Sameer Bakhshi   +2 more
doaj   +1 more source