Results 41 to 50 of about 93,615 (295)

Therapeutic targeting of the RB1 pathway in retinoblastoma with the oncolytic adenovirus VCN-01

open access: yesScience Translational Medicine, 2019
An oncolytic adenovirus shows antitumor efficacy in patient-derived models of intraocular retinoblastoma and appears safe for human use. An oncolytic virus to blast retinoblastoma Eyes afflicted by chemoresistant retinoblastoma may need to be surgically ...
Guillem Pascual-Pasto   +40 more
semanticscholar   +1 more source

MR Imaging Features to Differentiate Retinoblastoma from Coats’ Disease and Persistent Fetal Vasculature

open access: yesCancers, 2020
Simple Summary Retinoblastoma is a rare cancer that develops in the retina of children. Accurate differentiation between retinoblastoma and conditions that show similarities with retinoblastoma (pseudoretinoblastoma or retinoblastoma mimickers) is vital ...
Robin W. Jansen   +16 more
semanticscholar   +1 more source

Intra-arterial chemotherapy in retinoblastoma – A paradigm change

open access: yesIndian Journal of Ophthalmology, 2019
Intra-arterial chemotherapy (IAC), also known as superselective ophthalmic artery chemotherapy or chemosurgery, is currently widely accepted as one of the primary treatment modalities for intraocular retinoblastoma worldwide.
Fairooz P Manjandavida   +4 more
semanticscholar   +1 more source

Retinoblastoma: A spectrum of manifestations in three cases on B-scan

open access: yesIndian Journal of Radiology and Imaging, 2007
Retinoblastoma is a primary intraocular neoplasm of childhood, presenting with leukocoria.We present a spectrum of three cases. First two cases are of bilateral retinoblastoma and last case is a retinoblastoma of right eye.
V. D. Aironi   +3 more
doaj   +1 more source

Inhibitory activity of bevacizumab to differentiation of retinoblastoma cells. [PDF]

open access: yesPLoS ONE, 2012
Vascular endothelial growth factor (VEGF) is a major regulator in retinal and choroidal angiogenesis, which are common causes of blindness in all age groups.
Jang Won Heo   +6 more
doaj   +1 more source

Circular RNA hsa_circ_0000034 promotes the progression of retinoblastoma via sponging microRNA-361-3p

open access: yesBioengineered, 2020
Retinoblastoma is the commonest eye cancer occurring in the pediatric population. Circular RNAs (circRNAs) are essential regulators of tumorigenesis and development.
Zhe Sun, Ai Zhang, Mingyu Hou, T. Jiang
semanticscholar   +1 more source

Current therapy and recent advances in the management of retinoblastoma

open access: yesIndian Journal of Medical and Paediatric Oncology, 2012
Retinoblastoma is the most common intraocular malignancy in children. The survival of retinoblastoma patients and visual outcome has improved dramatically in the developed world.
Rachna Meel   +2 more
doaj   +1 more source

Retinoblastoma in an adult [PDF]

open access: yesBMC Research Notes, 2013
Retinoblastoma is the most common pediatric ocular tumour. It may rarely present in adults. The present case adds to the number of 26 cases already published in literature since 1919 till 2013. Our aim is to highlight the rare occurrence of retinoblastoma in adults along with its features which differentiate it from paediatric retinoblastoma.We ...
Nadeem Zafar   +2 more
openaire   +3 more sources

Differentiating MYCN-amplified RB1 wild-type retinoblastoma from biallelic RB1 mutant retinoblastoma using MR-based radiomics: a retrospective multicenter case–control study

open access: yesScientific Reports
MYCN-amplified RB1 wild-type (MYCN amp RB1 +/+) retinoblastoma is a rare and aggressive subtype, often resistant to standard therapies. Identifying unique MRI features is crucial for diagnosing this subtype, as biopsy is not recommended. This study aimed
Christiaan M. de Bloeme   +28 more
doaj   +1 more source

Adjuvant therapy for children treated by enucleation at diagnosis of retinoblastoma

open access: yesEJC Paediatric Oncology, 2023
Introduction: Advanced localized retinoblastoma can be cured by enucleation, but extraocular spread of retinoblastoma cells is associated with a high mortality.
Yelena Diarra   +27 more
doaj   +1 more source

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