Results 41 to 50 of about 57,195 (184)

The retinoblastoma tumor suppressor modulates DNA repair and radioresponsiveness. [PDF]

, 2014
PURPOSE: Perturbations in the retinoblastoma pathway are over-represented in advanced prostate cancer; retinoblastoma loss promotes bypass of first-line hormone therapy.
Addya, Sankar, Birbe, Ruth, Boopathi, Ettickan, Ciment, Steve, Den, Robert, MD, Dicker, Adam, MD, PhD, Ertel, Adam, Fortina, Paolo, Knudsen, Karen E, Liu, Yi, McMahon, Steve B, Mellert, Hestia, O\u27Neill, Raymond, Sharma, Ankur, Thangavel, Chellappagounder   +14 more
core   +1 more source

Retinoblastoma in an adult [PDF]

BMC Research Notes, 2013
Retinoblastoma is the most common pediatric ocular tumour. It may rarely present in adults. The present case adds to the number of 26 cases already published in literature since 1919 till 2013. Our aim is to highlight the rare occurrence of retinoblastoma in adults along with its features which differentiate it from paediatric retinoblastoma.We ...
Nadeem Zafar, Saqib Q.ayyum Ahmad, Saemah Nuzhat Zafar   +2 more
openaire   +3 more sources

A rare case of adult onset retinoblastoma

Oman Journal of Ophthalmology, 2011
Retinoblastoma usually manifests before five years of age. Retinoblastoma in an adult is extremely rare. Twenty-three cases of retinoblastoma in adults 20 years or older have been reported in world literature.
Sunil Kumar Singh, Dipankar Das, Harsha Bhattacharjee, Jyotirmay Biswas, Ganesh Kuri, Kasturi Bhattacharjee, Hemlata Deka, Akshay Chandra Deka   +7 more
doaj   +1 more source

Sclero-conjunctival ischaemia secondary to intra-arterial chemotherapy for retinoblastoma

American Journal of Ophthalmology Case Reports, 2020
Purpose: Intra-arterial chemotherapy (IAC), delivered directly to the globe via the internal carotid artery is now an established treatment for retinoblastoma.
Lisa McAnena, Zishan Naeem, Catriona Duncan, Fergus Robertson, Mandeep S. Sagoo, M. Ashwin Reddy   +5 more
doaj  

MiR-613 suppresses retinoblastoma cell proliferation, invasion, and tumor formation by targeting E2F5

Tumor Biology, 2017
Retinoblastoma is a common intraocular malignancy that occurs during childhood. MicroRNAs play critical roles in the regulation of retinoblastoma initiation and progression, and aberrant expression of miR-613 had been reported in various types of cancer.
Yiting Zhang, Xinyue Zhu, Xiaomin Zhu, Yan Wu, Yajun Liu, Borui Yao, Zhenping Huang   +6 more
doaj   +1 more source

Characterization of the Portuguese population diagnosed with retinoblastoma

Scientific Reports, 2022
The purpose of this study is to characterize demographically and genetically the Portuguese population with retinoblastoma; to report the clinical stage at presentation and its impact on survival and ocular preservation rate and, finally, to assess the ...
Guilherme Castela, Joana Providência, Madalena Monteiro, Sonia Silva, Manuel Brito, Joaquim Sá, Barbara Oliveiros, Joaquim Neto Murta, Zelia Correa, Miguel Castelo Branco   +9 more
doaj   +1 more source

DILEMA DALAM MANAJEMEN RETINOBLASTOMA

Majalah Kedokteran Andalas, 2014
Abstrak:Retinoblastoma merupakan keganasan intraokular tersering pada anak-anak. Deteksi dini memegang peranan penting dalam manajemen retinoblastoma karena sangat mempengaruhi prognosa.
Ardizal Rahman
doaj   +1 more source

Differentiating MYCN-amplified RB1 wild-type retinoblastoma from biallelic RB1 mutant retinoblastoma using MR-based radiomics: a retrospective multicenter case–control study

Scientific Reports
MYCN-amplified RB1 wild-type (MYCN amp RB1 +/+) retinoblastoma is a rare and aggressive subtype, often resistant to standard therapies. Identifying unique MRI features is crucial for diagnosing this subtype, as biopsy is not recommended. This study aimed
Christiaan M. de Bloeme , Robin W. Jansen, Liesbeth Cardoen, Sophia Göricke, Sabien van Elst, Jaime Lyn Jessen, Aparna Ramasubramanian, Alison H. Skalet, Audra K. Miller, Philippe Maeder, Ogul E. Uner, G. Baker Hubbard, Hans Grossniklaus, H. Culver Boldt, Kim E. Nichols, Rachel C. Brennan, Saugata Sen, Mériam Koob, Selma Sirin, Hervé J. Brisse, Paolo Galluzzi, Charlotte J. Dommering, Matthijs Cysouw, Ronald Boellaard, Josephine C. Dorsman, Annette C. Moll, Marcus C. de Jong, Pim de Graaf, European Retinoblastoma Imaging Collaboration   +28 more
doaj   +1 more source

Retinoblastoma: A spectrum of manifestations in three cases on B-scan

Indian Journal of Radiology and Imaging, 2007
Retinoblastoma is a primary intraocular neoplasm of childhood, presenting with leukocoria.We present a spectrum of three cases. First two cases are of bilateral retinoblastoma and last case is a retinoblastoma of right eye.
V. D. Aironi, Sonesh Chougule, Suneet Khetarpal, Gopalsingh Bhati   +3 more
doaj   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source