Results 41 to 50 of about 145,462 (345)
Longer Lag Time in Early-Stage Retinoblastoma
Folia Medica Indonesiana, 2022 Highlights: • Patients with IRSS I stage have the longest lag time than IVB stage. • Lag time is no significant with stage retinoblastoma. Abstract: Retinoblastoma is a rare neoplasm disease that occurs in children, generally under the age of ...
Anindya Citra +2 more
doaj +1 more source
Retinoblastoma in Late Childhood
Journal of Nepal Medical Association, 2003 Retinoblastoma, the commonest intra-ocular tumor of childhood, is rare after the age of 5 years. We report a case of retinoblastoma in a 10 year-old boy, who presented with a fungating proptosed tender mass involving the entire left eye and the orbit.
B Badhu, S P Sah, S Kumar, R P Sah
doaj +1 more source
Phosphorylation of pRb: mechanism for RB pathway inactivation in MYCN-amplified retinoblastoma. [PDF]
, 2017 A small, but unique subgroup of retinoblastoma has been identified with no detectable mutation in the retinoblastoma gene (RB1) and with high levels of MYCN gene amplification.
Bhatti, Tricia R. +6 more
core +2 more sources
OncoTargets and Therapy, 2020 Background MicroRNAs (miRNAs) have been shown to contribute to the initiation and progression of human cancer, including retinoblastoma. However, expression levels and potential roles of miRNAs in retinoblastoma remain largely unknown.
Lidong Yang +3 more
semanticscholar +1 more source
Thoracic Cancer, Volume 14, Issue 1, Page 68-72, January 2023., 2023 Abstract Objective Our study evaluated the renal safety of abemaciclib plus endocrine therapy (ET) with bisphosphonate as a treatment option for hormone receptor positive, human epidermal growth factor receptor 2 (HER‐2) negative (HR+/HER2−) advanced breast cancer (ABC), especially with bone metastasis.
Chunfang Hao +4 more
wiley +1 more source
Mutations in the RB1 Gene in Argentine Retinoblastoma Patients and Uncommon Clinical Presentations [PDF]
, 2015 Background: Retinoblastoma, the most common ocular cancer of childhood, is caused by inactivation of the RB1 tumor suppressor gene in the developing retina.
Alonso, Cristina +6 more
core +1 more source
Aging Cell, Volume 21, Issue 12, December 2022., 2022 Diabetes mellitus (DM) is a common chronic metabolic disease and an independent risk factor for atrial fibrillation (AF). However, the regulatory mechanisms underlying atrial electrical remodeling in diabetes are not fully understood. This study presents new insights into the role and mechanism of atrial myocyte senescence in diabetic‐induced AF ...
Dan‐Lin Zheng +13 more
wiley +1 more source
Analysis of MDM2 and MDM4 single nucleotide polymorphisms, mRNA splicing and protein expression in retinoblastoma. [PDF]
PLoS ONE, 2012 Retinoblastoma is a childhood cancer of the developing retina that begins in utero and is diagnosed in the first years of life. Biallelic RB1 gene inactivation is the initiating genetic lesion in retinoblastoma.
Justina McEvoy +6 more
doaj +1 more source
Early Prediction and Diagnosis of Retinoblastoma Using Deep Learning Techniques [PDF]
arXiv, 2021 Retinoblastoma is the most prominent childhood primary intraocular malignancy that impacts the vision of children and adults worldwide. In contrasting and comparing with adults it is uveal melanoma. It is an aggressive tumor that can fill and destroy the eye and the surrounding structures. Therefore early detection of retinoblastoma in childhood is the
arxiv
Retinoblastoma: Identifying the Diagnostic Signs for Early Treatment [PDF]
, 2015 Retinoblastoma is a rare but significant cause of childhood eye cancer world-wide. The prognosis depends upon early diagnosis and treatment but also upon accurate classification of the tumours.
Barratt, K. +4 more
core +2 more sources