Results 131 to 140 of about 5,117,644 (334)

Epigenotoxicity: Decoding the epigenetic imprints of genotoxic agents and their implications for regulatory genetic toxicology

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Regulatory genetic toxicology focuses on DNA damage and subsequent gene mutations. However, genotoxic agents can also affect epigenetic marks, and incorporation of epigenetic data into the regulatory framework may thus enhance the accuracy of risk assessment.
Roger Godschalk, Christopher Faulk, Jessica LaRocca, Jan van Benthem, Francesco Marchetti   +4 more
wiley   +1 more source

Pathways of Retinoic Acid and Retinol Metabolism

, 1969
Hector F. DeLuca, Anita B. Roberts
openalex   +1 more source

Genetic epilepsies with myoclonic seizures: Mechanisms and syndromes

Epilepsia Open, EarlyView.
Abstract Genetic epilepsy with myoclonic seizures encompasses a heterogeneous spectrum of conditions, ranging from benign and self‐limiting forms to severe, progressive disorders. While their causes are diverse, a significant proportion stems from genetic abnormalities.
Antonietta Coppola, Marica Rubino, Antonella Riva, Pasquale Striano   +3 more
wiley   +1 more source

Effects of dietary retinoic acid on cellular retinol- and retinoic acid-binding protein levels in various rat tissues.

Journal of Lipid Research, 1990
A study was conducted to explore the effects of retinoic acid, fed to retinol-deficient rats, on the tissue distribution and levels of cellular retinol-binding protein (CRBP) and cellular retinoic acid-binding protein (CRABP).
W S Blaner, K Das, J R Mertz, S R Das, D S Goodman   +4 more
doaj  

Oxidative decarboxylation of retinoic acid in microsomes of rat liver and kidney

, 1968
Anita B. Roberts, Hector F. DeLuca
openalex   +1 more source

Early retinoic acid-induced F9 teratocarcinoma stem cell gene ERA-1: alternate splicing creates transcripts for a homeobox-containing protein and one lacking the homeobox. [PDF]

, 1988
G J LaRosa, Lorraine J. Gudas
openalex   +1 more source

Microglial Activation and Inflammatory Responses in Parkinson's Disease Models Are Attenuated by TRPM2 Depletion

Glia, EarlyView.
Trpm2 partial and complete knockout reduce neuroinflammation in male and female mice. Microglial morphological changes are not found in Trpm2 knockout 6‐OHDA‐induced mice. TRPM2 is involved in microglial phagocytosis and IL1β, IL6, and iNOS expression. ABSTRACT Inflammation, and particularly microglial cells, has become a central feature in Parkinson's
Ana Flávia F. Ferreira, Zhong‐Ping Feng, Hong‐Shuo Sun, Luiz Roberto G. Britto   +3 more
wiley   +1 more source

Reciprocal TH17 and Regulatory T Cell Differentiation Mediated by Retinoic Acid

Science, 2007
D. Mucida, Yunji Park, Gisen Kim, O. Turovskaya, Iain Scott, M. Kronenberg, H. Cheroutre   +6 more
semanticscholar   +1 more source

Retinoic acid syndrome in a elderly male with psoriasis- A case report

Respiratory Medicine Case Reports, 2018
The retinoic acid derivatives are used for disorders of keratinization such as psoriasis. Retinoic acid syndrome is a cytokine release syndrome, commonly encountered in patients with acute promyelocytic leukaemia (APL).
Chandan Metage, Basanta Hazarika, Jogesh Sarma, Rahul Karwa   +3 more
doaj  

Vitamin A-Retinoic Acid Signaling Regulates Hematopoietic Stem Cell Dormancy

Cell, 2017
N. Cabezas-Wallscheid, F. Buettner, Pia Sommerkamp, Daniel Klimmeck, Luisa Ladel, F. Thalheimer, Daniel Pastor-Flores, L. Roma, Simon Renders, Petra Zeisberger, A. Przybylla, Katharina Schönberger, R. Scognamiglio, S. Altamura, Carolina M. Florian, Malak Fawaz, Dominik Vonficht, M. Tesio, Paul G Collier, D. Pavlinić, H. Geiger, T. Schroeder, V. Beneš, T. Dick, M. Rieger, O. Stegle, A. Trumpp   +26 more
semanticscholar   +1 more source