Results 201 to 210 of about 5,117,644 (334)

Single‐cell spatial transcriptomic sequencing and machine learning models uncover molecular mechanisms and diagnostic biomarkers of Peyronie's disease formation in rats

VIEW, EarlyView.
Peyronie's disease (PD) is a common male reproductive system disorder. The exact etiology of PD remains unclear. This study aimed to investigate molecular and cellular changes in PD using single‐cell spatial transcriptomics. Abstract Peyronie's disease (PD), commonly known as penile induration, is a prevalent male reproductive system disorder with ...
Keyuan Lou, Qiancheng Mao, Junpeng Chi, Jiankun Zhang, Hao Guo, Jitao Wu, Yuanshan Cui   +6 more
wiley   +1 more source

Mesenchymal retinoic acid signaling is required for normal diaphragm development in mice. [PDF]

FASEB J
Garcia Rivas JF, Applin NHM, Albrechtsen JFP, Ghazanfari A, Doschak M, Clugston RD.   +5 more
europepmc   +1 more source

Sevoflurane induces the inattention, cognitive impairment, and motor dysfunction by hypermethylation of retinoic acid receptor α in the medial prefrontal cortex of neonatal mice

VIEW, EarlyView.
The mechanisms underlying neurodevelopmental toxicity induced by repeated exposure to general anesthesia in neonatal mice remain to be fully elucidated. In this study, neonatal mice were exposed to sevoflurane on postnatal days 6, 8, and 10. On postnatal day 30, the medial prefrontal cortex was collected for whole‐genome bisulfite sequencing and RNA ...
Yu Hou, Shuai Li, Qi Hou, Runjia Wang, Zhenghao Deng, Xiyuan Xu, Zhichao Li, Linhui Ma, Yuan Shen, Qidong Liu, Hui Zheng   +10 more
wiley   +1 more source

Erratum: "Effects of Bisphenol A and Retinoic Acid Exposure on Neuron and Brain Formation: A Study in Human Induced Pluripotent Stem Cells and Zebrafish Embryos". [PDF]

Environ Health Perspect
Nishie T, Taya T, Omori S, Ueno K, Okamoto Y, Higaki S, Oka M, Mitsuishi Y, Tanaka T, Nakamoto M, Kawahara H, Teraguchi N, Kotaka T, Sawabe M, Takahashi M, Kitaike S, Wada M, Iida K, Yamashita A, Jinno H, Ichimura A, Tooyama I, Sakai N, Hibi M, Hirasawa A, Takada T.   +25 more
europepmc   +1 more source

Overexpression of the cellular retinoic acid binding protein-I (CRABP-I) results in a reduction in differentiation-specific gene expression in F9 teratocarcinoma cells. [PDF]

, 1991
J F Boylan, Lorraine J. Gudas
openalex   +1 more source

Role of NRP1/HDAC4/CREB/RIPK1 Axis in SARS‐CoV2 S1 Spike Subunit‐Induced Neuronal Toxicity

FASEB BioAdvances, EarlyView.
Extracellular SARS‐CoV2 Spike‐S1 protein via NRP1 internalizes in the cytosol of SH‐SY5Y cells. Once inside, it upregulates the epigenetic eraser HDAC4, which binds transcriptional factor CREB, causes RIPK1 up‐regulation, and therefore necroptotic cell death.
Luca Sanguigno, Natascia Guida, Mariarosaria Cammarota, Silvia Ruggiero, Angelo Serani, Francesca Galasso, Vincenzo Pizzorusso, Francesca Boscia, Luigi Formisano   +8 more
wiley   +1 more source

Notch3 enhances the synergistic effect of all-trans retinoic acid and calcipotriol in pancreatic stellate cell activation. [PDF]

J Transl Med
Lian Z, Du WH, Tusup-Han PG, Zhang YX.
europepmc   +1 more source

A retinoic acid responsive gene MK found in the teratocarcinoma system is expressed in spatially and temporally controlled manner during mouse embryogenesis. [PDF]

, 1990
Kenji Kadomatsu, R P Huang, Tatsuo Suganuma, F. Murata, Takashi Muramatsu   +4 more
openalex   +1 more source

Organ Specificity and Commonality of Epigenetic Aging in Low‐ and High‐Running Capacity Rats

Aging Cell, EarlyView.
Cardiorespiratory fitness (CRF) is not associated with epigenetic clocks, including newly developed ones. On the other hand, CRF is associated with global methylation profiles and promoter methylation in organ‐specific and organ‐common manner. ABSTRACT Epigenetic drift, which is gradual age‐related changes in DNA methylation patterns, plays a ...
Takuji Kawamura, Csaba Kerepesi, Juliet Polok Sarkar, Ferenc Torma, Zoltan Bori, Lei Zhou, Peter Bakonyi, Attila Kolonics, Laszlo Balogh, Mitsuru Higuchi, Vivien Pillár, Karolina Pircs, Lauren Gerard Koch, Steven Loyal Britton, Erika Koltai, Zsolt Radak   +15 more
wiley   +1 more source

Comparison of the Effectiveness of Fractional Carbon Dioxide Laser and Retinoic Acid Peel in the Treatment of Acanthosis Nigricans: A Randomized Controlled Trial. [PDF]

Cureus
Gnanasuriyan R, Shanmugam S.
europepmc   +1 more source