Results 211 to 220 of about 223,790 (352)

Recruitment of Nuclear Receptor Corepressor and Coactivator to the Retinoic Acid Receptor by Retinoid Ligands [PDF]

, 2000
Elliott Klein, Jenny W. Wang, Berket Khalifa, Stacey A. Gavigan, Roshantha A.S. Chandraratna   +4 more
openalex   +1 more source

Transcriptional regulation of human NMNAT2: insights from 3D genome sequencing and bioinformatics

The FEBS Journal, EarlyView.
NMNAT2 is a valuable drug target, as low levels increase the risk of neurodegeneration. We employed 4C‐seq to identify NMNAT2 regulatory regions in the human genome, revealing distinct interactomes of the NMNAT2 promoter in undifferentiated and neuron‐like SH‐SY5Y cells. Additionally, we uncovered NMNAT2‐associated genes and transcription factors. This
Yu Chen Chang, Sen Yang, Minyoung Cho, Kwangsik Nho, José‐Manuel Baizabal, Hui‐Chen Lu   +5 more
wiley   +1 more source

All-Trans Retinoic Acid Attenuates Inflammation and Insulin Resistance Induced by Adipocyte-Macrophage Coculture. [PDF]

Molecules
Baek KR, Kim HK.
europepmc   +1 more source

Influence of all-trans retinoic acid on pigmentation and skeletal formation in larval Japanese flounder

, 2002
Yutaka Haga, Toshio Takeuchi, Tadahisa Seikai   +2 more
openalex   +2 more sources

Hypoxia regulates Th17/Treg balance by altering chromatin accessibility and gene expression

The FEBS Journal, EarlyView.
T‐cell differentiation into Th17 or iTreg cells is key to inflammation control. Integrated RNA‐seq and ATAC‐seq analyses reveal that hypoxia induces more extensive gene expression changes in iTreg cells. Elevated levels of Hif1a and Stat3, along with increased accessibility to key transcription factor motifs, may predispose these cells toward ...
Mariana Cázares‐Olivera, Shiyang Song, Sofia Ylinen, Talha Qureshi, Bin Li, Zhi Chen   +5 more
wiley   +1 more source

Effect of retinoic acid treatment on the retinoic acid signaling pathway in a human siRNA-based aniridia limbal epithelial cell model, in vitro. [PDF]

PLoS One
Hsu SL, Stachon T, Fries FN, Li Z, Li S, Liu S, Seitz B, Kundu S, Amini M, Suiwal S, Szentmáry N.   +10 more
europepmc   +1 more source

Running increases neurogenesis without retinoic acid receptor activation in the adult mouse dentate gyrus [PDF]

, 2008
Elin Åberg, Thomas Perlmann, Luis B. Tovar‐y‐Romo, Stefan Brené   +3 more
openalex   +1 more source

MAVS oligomerization drives a faster and more efficient antiviral signaling activation at peroxisomes compared to mitochondria

The FEBS Journal, EarlyView.
Cells rely on mitochondria and peroxisomes to trigger antiviral defenses via the protein MAVS. This manuscript demonstrates that the robust production of antiviral effectors resulting from MAVS activation at peroxisomes is faster than at mitochondria due to a swifter oligomerization of this protein at peroxisomal membranes. These results underscore the
Bruno Ramos, Jéssica Sarabando, Mariana Marques, Jonathan C. Kagan, Daniela Ribeiro   +4 more
wiley   +1 more source

Understanding the Role of All-Trans Retinoic Acid in Acute Myeloid Leukemia Cells. [PDF]

World J Oncol
Al Sadoun H, Alamoudi F, Alamoudi N, Tayeb H, Felimban R, Alserihi R, Yasin EB, Khan R, Noorwali AW.   +8 more
europepmc   +1 more source

3′UTR variants of ALS‐linked RNAs modify subcellular and cellular phenotypes

The FEBS Journal, EarlyView.
Our study demonstrates that alternative 3′UTR variants of ALS‐linked transcripts modulate subcellular RNA localization and cytoskeletal architecture. NEFH 3′UTR‐Long promotes nuclear RNA clustering, while SOD1 3′UTR‐Long reduces filopodia formation. These results suggest that 3′UTRs, independent of coding sequences, can influence neuronal phenotypes ...
Melis Savasan‐Sogut, Danae Campos‐Melo, Michael J. Strong   +2 more
wiley   +1 more source