Results 251 to 260 of about 222,098 (349)

Histiocytes: Multifaceted Regulators of Health and Disease

Veterinary Clinical Pathology, EarlyView.
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley   +1 more source

TDG orchestrates ATF4-dependent gene transcription during retinoic acid-induced cell fate acquisition. [PDF]

Nucleic Acids Res
Turpin M, Madigou T, Bizot M, Acker R, Avner S, Benot G, Braud M, Fourgeux C, Palierne G, Poschmann J, Sawvell K, Watrin E, Péron CL, Salbert G.   +13 more
europepmc   +1 more source

Dietary interventions in acute kidney injury: From molecular mechanism to clinical trials

Experimental Physiology, EarlyView.
Abstract Ageing impairs renal resilience with an elevated risk of frequent and harmful acute kidney injury (AKI) that causes substantial morbidity and mortality among hospitalized patients. Since different damaging stimuli at the molecular, cellular and functional level contribute to this loss in kidney function, AKI's pathophysiology is heterogeneous ...
Felix C. Koehler, Pedro Rojas‐Morales, Roman‐Ulrich Müller   +2 more
wiley   +1 more source

Understanding the Role of All-Trans Retinoic Acid in Acute Myeloid Leukemia Cells. [PDF]

World J Oncol
Al Sadoun H, Alamoudi F, Alamoudi N, Tayeb H, Felimban R, Alserihi R, Yasin EB, Khan R, Noorwali AW.   +8 more
europepmc   +1 more source

In silico modelling of multi‐electrode arrays for enhancing cardiac drug testing on hiPSC‐CM heterogeneous tissues

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the experimental and computational framework for investigating hiPSC‐CM electrophysiology with MEA systems. The MEA‐based model integrates experimental data with phenotype‐specific ionic models and tissue‐level heterogeneity.
Sofia Botti, Rolf Krause, Luca F. Pavarino   +2 more
wiley   +1 more source

Antitumor Activity of All-Trans Retinoic Acid and Curcumin-Loaded BSA Nanoparticles Against U87 Glioblastoma Cells. [PDF]

Life (Basel)
Sonmez C, Baltacioglu A, Coskun J, Demirbolat GM, Gok O, Ozpinar A.   +5 more
europepmc   +1 more source

Blebbistatin reduces calcium buffering in cardiomyocytes: Consequences for cellular electrophysiology

The Journal of Physiology, EarlyView.
Abstract figure legend Blebbistatin reduces Ca2+ buffering in induced pluripotent stem cell‐derived atrial cardiomyocytes. Blebbistatin, a widely used excitation–contraction uncoupling agent, decreases calcium (Ca2+) buffer affinity (increased buffer dissociation constant), leading to elevated diastolic Ca2+ levels, increased sarcoplasmic reticulum Ca2+
Izzatullo Sobitov, Katharina Ritzenhoff, Marie Gaulrapp, Lea Becker, Aiste Liutkute, Fitzwilliam Seibertz, Funsho E. Fakuade, Fleur E. Mason, Niels Voigt   +8 more
wiley   +1 more source

Retinoic acid and ascorbate synergize to suppress myeloid leukemia via TET2 activation. [PDF]

Cell Rep
Leesang TE, Brabson JP, Yap YS, Barbieri DA, Klimas AS, Pinzone J, Ahearn EL, Lam MQ, Lyon PD, Swirski A, Wolfe NB, Nakata Y, Dos Santos HG, Shiekhattar R, Morey L, Vlantis PI, Figueroa ME, Chandhok N, Beckedorff F, Telonis AG, Cimmino L.   +20 more
europepmc   +1 more source

Half-site spacing and orientation determines whether thyroid hormone and retinoic acid receptors and related factors bind to DNA response elements as monomers, homodimers, or heterodimers

, 1992
B. M. Forman
openalex   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source