Results 41 to 50 of about 6,065,806 (347)

Detection and mode of action of retinoids on ovarian development in the mud crab, Scylla serrata

International Journal of Aquatic Biology, 2019
In the current study, the retinoic acid isomers such as 9-cis retinoic acid and all-trans retinoic acid were detected in the mature ovaries of mud crabs, Scylla serrata using HPLC analysis.
Kaduru Venkaiah, Daveedu Thathapudi, Sri Bhashyam Sainath   +2 more
doaj   +1 more source

Potential Therapeutic Effect of All-Trans Retinoic Acid on Atherosclerosis

Biomolecules, 2022
Atherosclerosis is a major risk factor for myocardial infarction and ischemic stroke, which are the leading cause of death worldwide. All-trans retinoic acid (ATRA) is a natural derivative of essential vitamin A.
Qile Deng, Jixiang Chen
doaj   +1 more source

Impact of Retinoic Acid on Immune Cells and Inflammatory Diseases

Mediators of Inflammation, 2018
Vitamin A metabolite retinoic acid (RA) plays important roles in cell growth, differentiation, organogenesis, and reproduction and a key role in mucosal immune responses.
L. Oliveira, F. Teixeira, M. Sato
semanticscholar   +1 more source

Maternal smoking and the retinoid pathway in the developing lung

Respiratory Research, 2012
Background Maternal smoking is a risk factor for pediatric lung disease, including asthma. Animal models suggest that maternal smoking causes defective alveolarization in the offspring.
Manoli Sara E, Smith Lacey A, Vyhlidal Carrie A, An Chang, Porrata Yolanda, Cardoso Wellington V, Baron Rebecca M, Haley Kathleen J   +7 more
doaj   +1 more source

Pathogenesis of retinoic acid-induced spina bifida in rat embryos

, 2008
In a previous study, we showed that the intrauterine exposure of rat embryos to retinoic acid (RA) in the organogenesis period (8-11 days of gestation) induced various malformations according to the dose and timing of RA administration.
コニシ, ヒロヨシ, 小西, 啓悦, 1430, Konishi, Hiroyoshi   +3 more
core   +1 more source

In vivo biosynthesis of retinoic acid from beta-carotene involves and excentric cleavage pathway in ferret intestine

Journal of Lipid Research, 1996
This study was done to determine whether retinoic acid can be produced by excentric cleavage of beta-carotene in vivo. By using an inhibitor of retinaldehyde oxidation, citral, either retinaldehyde or beta-carotene was incorporated in a micellar solution
X Hébuterne, X D Wang, D E Smith, G Tang, R M Russell   +4 more
doaj   +1 more source

Retinoic acid and arsenic trioxide for acute promyelocytic leukemia.

New England Journal of Medicine, 2013
BACKGROUND All-trans retinoic acid (ATRA) with chemotherapy is the standard of care for acute promyelocytic leukemia (APL), resulting in cure rates exceeding 80%.
F. Lo‐Coco, G. Avvisati, M. Vignetti, C. Thiede, S. Orlando, S. Iacobelli, F. Ferrara, P. Fazi, L. Cicconi, E. di Bona, G. Specchia, S. Sica, M. Divona, A. Levis, W. Fiedler, E. Cerqui, M. Breccia, G. Fioritoni, H. Salih, M. Cazzola, L. Melillo, A. Carella, C. Brandts, E. Morra, M. von Lilienfeld-Toal, B. Hertenstein, M. Wattad, M. Lübbert, M. Hänel, N. Schmitz, H. Link, M. Kropp, A. Rambaldi, G. La Nasa, M. Luppi, F. Ciceri, O. Finizio, A. Venditti, F. Fabbiano, K. Döhner, M. Sauer, A. Ganser, S. Amadori, F. Mandelli, H. Döhner, G. Ehninger, R. Schlenk, U. Platzbecker   +47 more
semanticscholar   +1 more source

1,25(OH)2 vitamin D3, and retinoic acid antagonize endothelin-stimulated hypertrophy of neonatal rat cardiac myocytes.

, 1996
1,25 (OH)(2) Vitamin D-3 (VD3) and retinoic acid (RA) function as ligands for nuclear receptors which regulate transcription, Though the cardiovascular system is not thought to represent a classical target for these ligands, it is clear that both cardiac
Gardner, D. G., J Wu, Garami, Miklós, Cheng, T., T Cheng, Wu, J., M Garami, D G Gardner   +7 more
core   +1 more source

A Role for All-Trans-Retinoic Acid in the Early Steps of Lymphatic Vasculature Development [PDF]

, 2010
The molecular mechanisms that regulate the earliest steps of lymphatic vascular system development are unknown. To identify regulators of lymphatic competence and commitment, we used an in vitro vascular assay with mouse embryonic stem cell-derived ...
Dabouras, Vasilios, Marino, Daniela, Vasilios Dabouras, Detmar, Michael, Braendli, Andre W., Michael Detmar, André W. Brändli, Daniela Marino   +7 more
core   +1 more source

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid–inducible gene-I and melanoma differentiation–associated gene 5

Journal of Experimental Medicine, 2008
The ribonucleic acid (RNA) helicases retinoic acid-inducible gene-I (RIG-I) and melanoma differentiation–associated gene 5 (MDA5) recognize distinct viral and synthetic RNAs, leading to the production of interferons.
H. Kato, O. Takeuchi, Eriko Mikamo-Satoh, R. Hirai, T. Kawai, Kazufumi Matsushita, Akane Hiiragi, T. Dermody, T. Fujita, S. Akira   +9 more
semanticscholar   +1 more source