Results 61 to 70 of about 357,868 (360)
Retinoic acids are natural derivatives of vitamin A, and play important roles in modulating tumor cell growth by regulating differentiation, thus suggesting the potential use of these derivatives in cancer therapy and prevention.
Min Kyung So+8 more
doaj +1 more source
The development of the aortic arch is a complex process that involves remodeling of the bilaterally symmetrical pharyngeal arch arteries (PAAs) into the mature asymmetric aortic arch.
Kelsey F. Sugrue+3 more
doaj +1 more source
Ligand-dependent dynamics of retinoic acid receptor binding during early neurogenesis
BackgroundAmong its many roles in development, retinoic acid determines the anterior-posterior identity of differentiating motor neurons by activating retinoic acid receptor (RAR)-mediated transcription.
Shaun Mahony+5 more
semanticscholar +1 more source
Integration of Bioengineered Tools in Assisted Reproductive Technologies
A conceptual illustration depicting the collaboration between a medical professional (right) and a scientist (left). Their connection highlights the integration of scientific research and clinical practice. This representation underscores the role of emerging technologies in bridging fundamental research with applied reproductive healthcare.
Aslı Ak+3 more
wiley +1 more source
The objective of the present study was to determine the effects of retinoic acid on the growth of the mouse mammary cells HC11 and HC11ras, which are a model for in vitro breast cancer progression.
Snitcovsky I.+3 more
doaj
Retinoic Acid Receptor β Expression in Oral Precancer Progression
Aim or Purpose: The burden of Oral Squamous Cell Carcinoma (OSCC) is huge because of the permanent impairment, high mortality and associated high cost of treatment. OSCC is often preceded by oral pre-cancer lesions/conditions (PMDs).
Prof Shaleen Chandra+2 more
doaj
Additive Effects of Retinoic Acid (RA) and Bone Morphogenetic Protein 4 (BMP-4) Apoptosis Signaling in Retinoblastoma Cell Lines. [PDF]
Retinoids have been shown to serve promising therapeutic agents for human cancers, e.g. the treatment of neuroblastoma. Synthetic retinoids, specific for particular retinoic acid (RA) receptors, are tested as new therapy strategies. In the present study,
Patrick Müller+5 more
doaj +1 more source
RARA (Retinoic acid receptor, alpha) [PDF]
Review on RARA (retinoic acid receptor, alpha), with data on DNA, on the protein encoded, and where the gene is implicated.
openaire +4 more sources
Here we investigated a pharmacological approach to inhibit spermatogenesis in the mouse model by manipulating retinoid signaling using low doses of the pan-retinoic acid receptor (RAR) antagonist BMS-189453.
Sanny S. W. Chung+5 more
semanticscholar +1 more source
An ex vivo glomerular filtration barrier is engineered using electrospun, biomimetic membranes seeded with human glomerular cells. The model supports fenestrated endothelium and podocyte foot processes under flow, mimics size‐selective filtration, and enables disease modeling with hiPSC‐derived podocytes, offering a powerful platform for studying ...
Camilla Mussoni+8 more
wiley +1 more source