Results 61 to 70 of about 357,868 (360)

In Vivo Imaging of Retinoic Acid Receptor Activity using a Sodium/Iodide Symporter and Luciferase Dual Imaging Reporter Gene

open access: yesMolecular Imaging, 2004
Retinoic acids are natural derivatives of vitamin A, and play important roles in modulating tumor cell growth by regulating differentiation, thus suggesting the potential use of these derivatives in cancer therapy and prevention.
Min Kyung So   +8 more
doaj   +1 more source

The ubiquitin ligase HECTD1 promotes retinoic acid signaling required for development of the aortic arch

open access: yesDisease Models & Mechanisms, 2019
The development of the aortic arch is a complex process that involves remodeling of the bilaterally symmetrical pharyngeal arch arteries (PAAs) into the mature asymmetric aortic arch.
Kelsey F. Sugrue   +3 more
doaj   +1 more source

Ligand-dependent dynamics of retinoic acid receptor binding during early neurogenesis

open access: yesGenome Biology, 2011
BackgroundAmong its many roles in development, retinoic acid determines the anterior-posterior identity of differentiating motor neurons by activating retinoic acid receptor (RAR)-mediated transcription.
Shaun Mahony   +5 more
semanticscholar   +1 more source

Integration of Bioengineered Tools in Assisted Reproductive Technologies

open access: yesAdvanced Healthcare Materials, EarlyView.
A conceptual illustration depicting the collaboration between a medical professional (right) and a scientist (left). Their connection highlights the integration of scientific research and clinical practice. This representation underscores the role of emerging technologies in bridging fundamental research with applied reproductive healthcare.
Aslı Ak   +3 more
wiley   +1 more source

Normal HC11 and ras-transformed mouse mammary cells are resistant to the antiproliferative effects of retinoic acid

open access: yesBrazilian Journal of Medical and Biological Research, 2003
The objective of the present study was to determine the effects of retinoic acid on the growth of the mouse mammary cells HC11 and HC11ras, which are a model for in vitro breast cancer progression.
Snitcovsky I.   +3 more
doaj  

Retinoic Acid Receptor β Expression in Oral Precancer Progression

open access: yesInternational Dental Journal, 2023
Aim or Purpose: The burden of Oral Squamous Cell Carcinoma (OSCC) is huge because of the permanent impairment, high mortality and associated high cost of treatment. OSCC is often preceded by oral pre-cancer lesions/conditions (PMDs).
Prof Shaleen Chandra   +2 more
doaj  

Additive Effects of Retinoic Acid (RA) and Bone Morphogenetic Protein 4 (BMP-4) Apoptosis Signaling in Retinoblastoma Cell Lines. [PDF]

open access: yesPLoS ONE, 2015
Retinoids have been shown to serve promising therapeutic agents for human cancers, e.g. the treatment of neuroblastoma. Synthetic retinoids, specific for particular retinoic acid (RA) receptors, are tested as new therapy strategies. In the present study,
Patrick Müller   +5 more
doaj   +1 more source

RARA (Retinoic acid receptor, alpha) [PDF]

open access: yesAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on RARA (retinoic acid receptor, alpha), with data on DNA, on the protein encoded, and where the gene is implicated.
openaire   +4 more sources

Oral administration of a retinoic Acid receptor antagonist reversibly inhibits spermatogenesis in mice.

open access: yesEndocrinology, 2011
Here we investigated a pharmacological approach to inhibit spermatogenesis in the mouse model by manipulating retinoid signaling using low doses of the pan-retinoic acid receptor (RAR) antagonist BMS-189453.
Sanny S. W. Chung   +5 more
semanticscholar   +1 more source

Biofabrication of a Filtration Barrier by Integrating Electrospun Membranes and Flow in a Glomerular Co‐Culture

open access: yesAdvanced Healthcare Materials, EarlyView.
An ex vivo glomerular filtration barrier is engineered using electrospun, biomimetic membranes seeded with human glomerular cells. The model supports fenestrated endothelium and podocyte foot processes under flow, mimics size‐selective filtration, and enables disease modeling with hiPSC‐derived podocytes, offering a powerful platform for studying ...
Camilla Mussoni   +8 more
wiley   +1 more source

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