Retinoic acid-resistant HL-60 cells exclusively contain mutant retinoic acid receptor-alpha [PDF]
Yaping Li, F Said, RE Gallagher
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A tumour suppressive relationship between mineralocorticoid and retinoic acid receptors activates a transcriptional program consistent with a reverse Warburg effect in breast cancer. [PDF]
Doan TB+10 more
europepmc +1 more source
Multiple isoforms of the mouse retinoic acid receptor alpha are generated by alternative splicing and differential induction by retinoic acid. [PDF]
Pierre Leroy+7 more
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Structure-based analysis of the ultraspiracle protein and docking studies of putative ligands [PDF]
The ultraspiracle protein (USP) is the insect ortholog of the mammalian retinoid X receptor (RXR). Fundamental questions concern the functional role of USP as the heterodimerization partner of insect nuclear receptors such as the ecdysone receptor.
Billas, Isabelle M.L.+4 more
core +3 more sources
Retinoic acid (RA) serves as a metabolic intermediate of vitamin A. It plays a crucial physiological role in regulating cell proliferation, differentiation, apoptosis, embryonic development, and immunomodulation.
Wen Jia, Yang Bi
doaj +1 more source
Murine isoforms of retinoic acid receptor gamma with specific patterns of expression. [PDF]
P Kastner+7 more
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Somatic cell reprogramming for Parkinson's disease treatment
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley +1 more source
Retinoic acid (RA) regulates the transcription of a series of genes involved in cell proliferation, differentiation and apoptosis by binding to the RA Receptor (RAR) and Retinoid X Receptor (RXR) heterodimers.
Daniella de Barros Rossetto+4 more
doaj +2 more sources
Nuclear receptors for retinoic acid: Isolation of mouse cDNAs and human RARß genomic sequences
FrankA.E. Kruyt+4 more
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Rearrangements of the retinoic acid receptor alpha and promyelocytic leukemia zinc finger genes resulting from t(11;17)(q23;q21) in a patient with acute promyelocytic leukemia. [PDF]
S J Chen+8 more
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