The use of deidentified organ donor testes for research
Abstract Our knowledge of testis development and function mainly comes from research using mammalian model organisms, primarily the mouse. However, there are integral differences between men and other mammalian species regarding cellular composition and expression profiles during fetal and post‐natal testis development and in the mature testis ...
Marina V. Pryzhkova+4 more
wiley +1 more source
Antagonizing Retinoic Acid Receptors Increases Myeloid Cell Production by Cultured Human Hematopoietic Stem Cells. [PDF]
Brown G+4 more
europepmc +1 more source
Differential Transcriptional Regulation of the Apoal Gene by Retinoic Acid Receptor Homo- and Heterodimers in Yeast [PDF]
Anthony Salerno+4 more
openalex +1 more source
Molecular and cellular mechanisms underlying gyrate atrophy: Why is the retina primarily affected?
Abstract Gyrate atrophy of the choroid and retina (GACR; OMIM #258870) is a rare early‐onset autosomal recessive disorder, caused by bi‐allelic pathogenic variants in the gene coding for ornithine aminotransferase (OAT) resulting in hyperornithinaemia.
Mark J. N. Buijs+12 more
wiley +1 more source
Expression of retinoic acid-binding proteins and retinoic acid receptors in sebaceous cell carcinoma of the eyelids. [PDF]
Tsai YJ+7 more
europepmc +1 more source
Tissue-Specific Distribution of a Novel C-Terminal Truncation Retinoic Acid Receptor Mutant Which Acts as a Negative Repressor in a Promoter- and Cell-Type-Specific Manner [PDF]
Takashi Matsui, Shunsuke Sashihara
openalex +1 more source
ZIP10 as a potential therapeutic target in acute myeloid leukaemia
Increased intracellular zinc levels in acute myeloid leukaemia blasts with upregulated expression of zinc influx transporters ZIP6 and ZIP10. Targeting ZIP10 with a surface antibody represents a potential therapeutic strategy. Created in BioRender. Rolles, B. (2025) https://BioRender.com/bwrtof1.
Benjamin Rolles+18 more
wiley +1 more source
Simultaneous detection of type A and type B PML/retinoic acid receptor alpha fusion transcripts in acute promyelocytic leukemia [letter] [PDF]
Vikas Kohli, CA Koller
openalex +1 more source
The molecular physiology of nuclear retinoic acid receptors. From health to disease.
V. Duong, C. Rochette-Egly
semanticscholar +1 more source
HSV‐1 infection alters MAPT splicing and promotes Tau pathology in neural models of Alzheimer's disease. HSV‐1 infection in brain organoids and neuronal models increase 4R‐MAPT splicing and Tau hyperphosphorylation. HSV‐1 ICP27 is both necessary and sufficient for inducing these changes highlighting the potential role of HSV‐1 in Alzheimer's disease ...
Emmanuel C. Ijezie+9 more
wiley +1 more source