Results 231 to 240 of about 349,317 (300)

All-Trans Retinoic Acid Impacts Early Palatal Shelves Development via the Wnt and TGF-β Signaling Pathways. [PDF]

Biomedicines
Ma Y, Wang B, Gao S, Song T.
europepmc   +1 more source

Retinoic Acid Receptors Control Spermatogonia Cell-Fate and Induce Expression of the SALL4A Transcription Factor. [PDF]

PLoS Genet, 2015
Gely-Pernot A, Raverdeau M, Teletin M, Vernet N, Féret B, Klopfenstein M, Dennefeld C, Davidson I, Benoit G, Mark M, Ghyselinck NB.   +10 more
europepmc   +1 more source

Keratinocyte‐Associated Biomarkers Reveal Pathogenic Mechanisms in Acne

FASEB BioAdvances, Volume 8, Issue 2, February 2026.
The study workflow integrates scRNA‐seq and bulk RNA‐seq data to characterize acne pathogenesis. Step 1 identifies expanded keratinocyte populations using single‐cell analysis. Step 2 filters candidate genes via WGCNA and differential expression integration.
Sini Cai, Yinjing Lin, Heng Xie, Xian Ao, Qiwei Liu, Lining Huang   +5 more
wiley   +1 more source

Modifications of Cytochrome <i>c</i> by Retinoic Acid Play a Crucial Role in Mitochondrial Dysfunction of Triple-Positive Human Breast Cancer Cells: Raman Spectroscopy and Imaging Study. [PDF]

ACS Omega
Abramczyk H, Kopeć M, Surmacki J.
europepmc   +1 more source

Analysis of the all-trans retinoic acid (ATRA) and retinoic acid receptor-γ (RARγ/Rarg)-regulated transcriptomes in F9 cells

, 2015
D Su
openalex   +1 more source

Proximal Pulmonary Artery Stiffening as a Biomarker of Cardiopulmonary Aging

Aging Cell, Volume 25, Issue 2, February 2026.
Mouse models revealed age‐associated increased circumferential stiffness of the proximal pulmonary artery that was associated with reorientation of collagen and decreased function of the lung and right ventricle. Age‐related transcriptional changes were indicative of senescence, ECM turnover, TGFβ signaling, and altered intercellular signaling among ...
Ruben De Man, Zhongyu Cai, Pramath Doddaballapur, Nicole Guerrera, Alexandria Regan, Liqin Lin, Erica Schwarz, Aurelien Justet, Nebal S. Abu Hussein, Jack Di Palo, Cristina Cavinato, Micha Sam B. Raredon, Paul M. Heerdt, Inderjit Singh, Xiting Yan, Min‐Jong Kang, Danielle R. Bruns, Patty J. Lee, George Tellides, Jay D. Humphrey, Naftali Kaminski, Abhay B. Ramachandra, Edward P. Manning   +22 more
wiley   +1 more source

Modulation of axon excitable domains by astrocytes and microglia. [PDF]

Front Cell Neurosci
Garrido JJ.
europepmc   +1 more source

Dietary Protein Restriction Ameliorates Cardiac Inflammaging via AMPK‐ULK1‐Mediated Mitochondrial Quality Control

Aging Cell, Volume 25, Issue 2, February 2026.
Dietary protein restriction protects the aging heart in the context of obesity by limiting mitochondrial DNA leakage and suppressing cGAS–STING‐driven inflammation. Through AMPK–ULK1‐dependent mitophagy, protein restriction restores mitochondrial quality control, reduces cardiac remodeling, and preserves metabolic homeostasis during obesity‐associated ...
Wagner S. Dantas, Elizabeth R. M. Zunica, Elizabeth C. Heintz, Charles L. Hoppel, Cristal M. Hill, Christopher D. Morrison, Christopher L. Axelrod, Gangarao Davuluri, John P. Kirwan   +8 more
wiley   +1 more source

Signaling through retinoic acid receptors in cardiac development: Doing the right things at the right times. [PDF]

Biochim Biophys Acta, 2015
Xavier-Neto J, Sousa Costa ÂM, Figueira AC, Caiaffa CD, Amaral FN, Peres LM, da Silva BS, Santos LN, Moise AR, Castillo HA.   +9 more
europepmc   +1 more source

Comparative multi‐omics in female mice reveals tissue‐specific vulnerabilities to chronic alcohol intake

Alcohol, Clinical and Experimental Research, Volume 50, Issue 2, February 2026.
Using mice, we applied multi‐omics to compare liver and skeletal muscle after chronic alcohol consumption. The liver responded more strongly across genes, proteins, and metabolites, with a lowered PC:PE ratio. Muscle showed inflammation, extracellular matrix activation, impaired mitochondrial energetics, and an elevated PC:PE ratio. Lipidomics affected
Craig R. G. Willis, Muni Swamy Ganjayi, Austin M. Brown, Samantha E. Moser, Nathaniel J. Szewczyk, Brian C. Clark, Cory W. Baumann   +6 more
wiley   +1 more source