Results 101 to 110 of about 50,541 (213)

Dissecting Cellulitis and Hidradenitis Suppurativa: Two Diseases or One Follicular‐Occlusion Spectrum?

International Journal of Dermatology, EarlyView.
Graphical abstract summarizing evidence that dissecting cellulitis of the scalp (DC) and hidradenitis suppurativa (HS) may represent site‐modified expressions of a shared follicular‐occlusion pathway, highlighting convergent clinical, histopathologic, and therapeutic features, the diagnostic‐context paradox, and the need for paired molecular studies ...
Giuseppe Gallo, Federica Repetto, Orsola Crespi, Isotta Giunipero di Corteranzo, Luca Mastorino, Pietro Quaglino, Simone Ribero   +6 more
wiley   +1 more source

Intracellular Retinoid-Binding Proteins (CRBP, CRALBP, CRABP) as Emerging Drug Targets in Retinal Disease. [PDF]

Int J Mol Sci
Regmi Bagale L, Kim HJ.
europepmc   +1 more source

Scalp Dysesthesia: Emerging Pathophysiologic Insights and Therapeutic Implications

International Journal of Dermatology, EarlyView.
Scalp dysesthesia is a chronic condition diagnosed through exclusion. This scoping review synthesized data from 59 patients to identify recurrent clinical features, comorbidities, and management strategies that may support earlier diagnosis. Emerging patterns suggest that neuronal sensitization may underlie common symptoms.
Aditya K. Gupta, Jaspreet Kaur, Amanda Liddy, Paradi Mirmirani, Vincent Piguet   +4 more
wiley   +1 more source

Cumulative isotretinoin dosing, treatment response and acne relapse: A randomized controlled trial

Journal of the European Academy of Dermatology and Venereology, EarlyView.
In this randomized controlled trial, cumulative isotretinoin doses of 120 and 150 mg/kg showed similar relapse rates at 12 months. Both regimens achieved substantial and comparable reductions in inflammatory acne lesions across the face, chest and back.
Ruggero Cascio Ingurgio, Angela Alfano, Antonio Costanzo, Julie S. Cronk, Rebecca Cummins, Benjamin S. Daniel, Ben J. Koszegi, Linda K. Martin, Clarisse G. Mendoza, Mae Ramirez‐Quizon, Lesley M. Rhodes, Heather I. Rishel, Adam I. Rubin, Fanny Satgé, Supriya Venugopal, Anna Wilson, Dedee F. Murrell   +16 more
wiley   +1 more source

Lipid-Retinoid Metabolic Network Links Genetic Variation to Molecular Heterogeneity in Inherited Retinal Degeneration. [PDF]

Int J Mol Sci
Sołek P, Cholewińska E, Rejdak R, Nowomiejska K, Ognik K.   +4 more
europepmc   +1 more source

Male genital lichen sclerosus

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Male genital lichen sclerosus is driven by chronic, occluded exposure of susceptible genital epithelium to urine, rather than infection or autoimmunity. This review synthesizes clinical, anatomical and molecular evidence showing how microincontinence and occlusion initiate inflammation, fibrosis and carcinogenesis, and explains the curative effect of ...
Georgios Kravvas, Rory Barry, Richard E. Watchorn, Christopher B. Bunker   +3 more
wiley   +1 more source

Topical retinoids and risk of major congenital malformations and spontaneous abortion: a systematic review and meta-analysis. [PDF]

Front Drug Saf Regul
Alali AB, Alhammad FA, Almohammed Saleh JA, Alshaikh SB, Alshayeb ZK, Al Nujaidi AJ, Albinsaleh AA, Almutawah MR, Alhodibi MH, Albesher MA.   +9 more
europepmc   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger, Yuxi Zhou, Jiawen Yong, Lei Wang, Sabine Ruf, Joerg Meyle   +5 more
wiley   +1 more source

Conformational signatures of native ligand and pharmacochaperone binding in rhodopsin. [PDF]

Structure
Pashandi Z, Ortega JT, Miyagi M, Golczak M, Jastrzebska B.   +4 more
europepmc   +1 more source

Established and Emerging Biomarkers to Characterize Persons at Risk for Obesity—Paving the Way for Targeted Clinical Intervention Trials—A Comprehensive Position Paper

Obesity Reviews, EarlyView.
ABSTRACT Despite all efforts, obesity remains a major health concern worldwide, with continuously increasing rates, affecting approx. 14% of the total world population, being as high as 43% in some countries. As obesity is related to numerous comorbidities, including type 2 diabetes, cardiovascular diseases, and some types of cancer, the consequences ...
Farhad Vahid, Victoria Stopa, Laurent Malisoux, Yvan Devaux, Elsa Lamy, Fernando Capela e Silva, Sarah Forberger, Tiziana de Magistris, Antoni Sureda, Margalida Monserrat‐Mesquida, Maria Pérez‐Jiménez, Rajini Nagrani, Maria Giovanna Onorati, Michele Filippo Fontefrancesco, Jonathan Turner, Mahesh S. Desai, Josep Tur, Cristina Bouzas, Gino Gabriel Bonetti, Oliver Riedel, Gitte Ravn‐Haren, Rikke Andersen, Torsten Bohn   +22 more
wiley   +1 more source