Trifarotene Reduces Risk for Atrophic Acne Scars: Results from A Phase 4 Controlled Study [PDF]
Dermatology and Therapy, 2023 Background Atrophic acne scarring often accompanies acne vulgaris. The efficacy of topical retinoids for treatment of acne is well documented; however, evidence for use in atrophic acne scars is limited.
Rajeev Chavda, James del Rosso
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Trifarotene: A Novel Therapeutic Option for Acne [PDF]
Dermatology Research and Practice, 2022 Acne vulgaris, or acne, is a prevailing cutaneous predicament that customarily crops up on the face, neck, and trunk in the forms of comedones, papules, pustules, and nodules.
Piyu Parth Naik
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A Real-World Approach to Trifarotene Treatment in Patients with Acne and Acne Sequelae Based on the Experience of the Italian Acne Board [PDF]
Dermatology and TherapyAcne and acne sequelae can have an important impact on patients’ quality of life, affecting interpersonal relationships and social functioning. Acne-induced scars (AIS) and acne-induced macular hyperpigmentation (AIH), in particular, are a major concern ...
Giuseppe Monfrecola, Vincenzo Bettoli
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Trifarotene: A Current Review and Perspectives in Dermatology
Biomedicines, 2021 Retinoids have numerous applications in inflammatory, dyskeratotic, and oncohematology diseases. Retinoids have now reached the fourth generation, progressively reducing toxicity whilst increasing their efficacy.
Augusto Orlandi, Luca Bianchi
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Transcriptomics Analysis Indicates Trifarotene Reverses Acne-Related Gene Expression Changes
Frontiers in Medicine, 2021 Background and Objectives: Trifarotene is a topical retinoid selective for retinoic acid receptor gamma that was recently approved for treatment of acne vulgaris.
Sandrine Blanchet-Réthoré +1 more
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Journal of Dermatological Treatment, 2023 Background Irritation with topical retinoids presents a significant impediment to acne treatment adherence. Two studies assessed the irritation potential of tazarotene 0.045% lotion versus adapalene 0.3% gel and trifarotene 0.005% cream.
Zoe Draelos
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Potential Antifungal Activity of Retinoids Against Non-albicans Candida Species [PDF]
MicroorganismsNon-albicans Candida (NAC) species have emerged as significant opportunistic pathogens due to their reduced susceptibility to antifungal agents combined with their strong ability to form biofilms.
Terenzio Cosio +5 more
doaj +2 more sources
Topical Retinoids in Acne Vulgaris and Acne Scars—From Monotherapy to Combining Regimens [PDF]
PharmaceuticalsTopical retinoids are the cornerstone of the treatment of multiple dermatological conditions. Long established in acne therapy, they exert effects on keratinization, inflammation, fibroblast activity, and collagen remodeling, suggesting a potential role ...
Aleksandra Tobiasz +2 more
doaj +2 more sources
Retinoids as Alternative Antifungal Agents Against Candida albicans: In Vitro and In Silico Evidence [PDF]
MicroorganismsCandida albicans (C. albicans) is the most common pathogen responsible for a wide spectrum of human infections ranging from superficial mucocutaneous mycoses to systemic life-threatening diseases.
Terenzio Cosio +9 more
doaj +2 more sources
Assessing the Safety and Efficacy of Trifarotene in the Treatment of Acne Vulgaris
Therapeutics and Clinical Risk Management, 2021 Caitlin M Brumfiel,1 Meera H Patel,2 Katheryn A Bell,1 Michael A Cardis3 1Georgetown University School of Medicine, Washington, DC, USA; 2Creighton University School of Medicine, Phoenix Regional Campus, Phoenix, AZ, USA; 3MedStar Washington Hospital ...
Katheryn A Bell, Michael Cardis
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