Results 1 to 10 of about 2,534 (156)

Exploring Potential Therapeutic Applications of Tazarotene: Gene Regulation Mechanisms and Effects on Melanoma Cell Growth [PDF]

Current Issues in Molecular Biology
Tazarotene, a retinoid derivative, is widely used in treating skin conditions such as psoriasis and acne. Recent studies have demonstrated its potential as a promising therapeutic agent for treating melanoma in situ.
Lu-Kai Wang, Fu-Ming Tsai, Chun-Hua Wang   +2 more
exaly   +5 more sources

Improvements in acne and skin oiliness with tazarotene 0.045% lotion in patients with oily skin

Journal of Dermatological Treatment, 2023
Background Excessive sebum production is a factor in acne development. Tazarotene 0.045% lotion has demonstrated reductions in acne lesions and acne-induced sequelae. Objective Evaluate efficacy, changes in skin oiliness, and safety with tazarotene 0.045%
Emil A. Tanghetti, Joshua A. Zeichner, Michael Gold, Neil Sadick, Fran E. Cook-Bolden, Leon H. Kircik, Linda Stein Gold, Jonathan Weiss, Stephen K. Tyring, James Q. Del Rosso, Eric Guenin   +10 more
doaj   +2 more sources

Head-to-head comparison of tazarotene and calcitriol with or without sequential therapy in mild-to-moderate psoriasis: A randomized open-label study

Journal of Research in Pharmacy Practice, 2023
Objective: Psoriasis is an autoimmune disease that causes rapid turnover of skin cells. It is a chronic disease that affects a patient's quality of life significantly and frequently requires long-term treatment.
Jaspreet Kaur Sidhu, Prithpal Singh Matreja, Ashwani Kumar Gupta, Amandeep Singh, Surjit Singh   +4 more
doaj   +2 more sources

Low irritation potential of tazarotene 0.045% lotion: Head-to-head comparison to adapalene 0.3% gel and trifarotene 0.005% cream in two studies

Journal of Dermatological Treatment, 2023
Background Irritation with topical retinoids presents a significant impediment to acne treatment adherence. Two studies assessed the irritation potential of tazarotene 0.045% lotion versus adapalene 0.3% gel and trifarotene 0.005% cream.
Zoe Draelos
exaly   +2 more sources

Potential Antifungal Activity of Retinoids Against Non-albicans Candida Species [PDF]

Microorganisms
Non-albicans Candida (NAC) species have emerged as significant opportunistic pathogens due to their reduced susceptibility to antifungal agents combined with their strong ability to form biofilms.
Terenzio Cosio, Enrico Salvatore Pistoia, Francesca Pica, Augusto Orlandi, Elena Campione, Roberta Gaziano   +5 more
doaj   +2 more sources

Retinoids as Alternative Antifungal Agents Against Candida albicans: In Vitro and In Silico Evidence [PDF]

Microorganisms
Candida albicans (C. albicans) is the most common pathogen responsible for a wide spectrum of human infections ranging from superficial mucocutaneous mycoses to systemic life-threatening diseases.
Terenzio Cosio, Alice Romeo, Enrico Salvatore Pistoia, Francesca Pica, Claudia Freni, Federico Iacovelli, Augusto Orlandi, Mattia Falconi, Elena Campione, Roberta Gaziano   +9 more
doaj   +2 more sources

Retinoids enhance NK effector function against HIV-infected CD4 T cells [PDF]

Journal of Virology
Novel approaches to sensitize latently infected cells to apoptosis may provide additional methods to eliminate latent reservoirs. Prior research identified several retinoids as potential drugs that increase the sensitivity of HIV-infected cells to cell ...
Elyse K. McMahon, Jonathan S. Lochner, Rebecca M. Lynch, Alberto Bosque   +3 more
doaj   +2 more sources

Comparative efficacy of topical interventions for facial photoaging: a network meta-analysis [PDF]

Scientific Reports
Chronic ultraviolet (UV) exposure is the primary cause of skin photoaging, leading to wrinkles, pigmentation changes, and loss of dermal elasticity. This systematic review and network meta-analysis evaluated the efficacy and safety of topical compounds ...
Lulu Lin, Xueqing Chen, Chuanhui Liu, Qiting Wang, Weishan Lian, Xin Xu, Yawei Guo, Huiyuan Zhong, Jiangming Zhong, Nan Zhao, Weibin Cheng, Peng Shu, Zhongzhi Xu   +12 more
doaj   +2 more sources

Safety and efficacy of tazarotene foam for the treatment of acne vulgaris

Clinical, Cosmetic and Investigational Dermatology, 2013
Erica L Epstein, Linda Stein GoldHenry Ford Hospital, Detroit, MI, USABackground: Tazarotene foam is the first topical retinoid foam approved for the treatment of acne vulgaris.Objective: To review the safety and efficacy studies of tazarotene foam in ...
Linda Stein Gold
exaly   +2 more sources

Comparison of the Efficacy of Tazarotene 0.1% Cream Versus Clindamycin 1% Gel in the Treatment of Acne Vulgaris

Pakistan Armed Forces Medical Journal, 2022
Objective: To compare the efficacy of Tazarotene 0.1% cream versus Clindamycin 1% gel in treating acne vulgaris. Study Design: Quasi-experimental study.
Afnan Bin Haq, Zafar Iqbal Shaikh, Sadia Malik, Amir Ashraf, Syed Sajid Ali Shah, Ayesha Anwar   +5 more
doaj   +1 more source