Results 21 to 30 of about 131,717 (361)
Regulating Retinoic Acid Availability during Development and Regeneration: The Role of the CYP26 Enzymes. [PDF]
, 2020 This review focuses on the role of the Cytochrome p450 subfamily 26 (CYP26) retinoic acid (RA) degrading enzymes during development and regeneration. Cyp26 enzymes, along with retinoic acid synthesising enzymes, are absolutely required for RA homeostasis
Roberts, C
core +1 more source
The retina visual cycle is driven by cis retinol oxidation in the outer segments of cones [PDF]
, 2017 Vertebrate rod and cone photoreceptors require continuous supply of chromophore for regenerating their visual pigments after photoactivation. Cones, which mediate our daytime vision, demand a particularly rapid supply of 11-cis retinal chromophore in ...
Cornwall, M. Carter +3 more
core +2 more sources
Potential Effects of Oral Isotretinoin on Growth Plate and Height
Endocrines, 2023 Longitudinal growth and puberty are the result of a complex interaction of genetic, hormonal, nutritional, and environmental factors. Acne vulgaris is a chronic disease of the pilosebaceous unit that affects 85% of adolescents worldwide.
Adriane A. Cardoso-Demartini +2 more
doaj +1 more source
Journal of the American Academy of Dermatology, 1993 A 65-year-old woman treated with etretinate for pityriasis rubra pilaris developed chronic active hepatitis. The elevated transaminases were noted 2 months after initiation of therapy and peaked 2 months after discontinuation of etretinate. The spectrum of liver toxicity induced by etretinate is reviewed.
M R, Sanchez +5 more
openaire +2 more sources
Metabolic interactions between vitamin A and conjugated linoleic acid [PDF]
, 2014 Lipid-soluble molecules share several aspects of their physiology due to their common adaptations to a hydrophilic environment, and may interact to regulate their action in a tissue-specific manner.
BANNI, SEBASTIANO +7 more
core +2 more sources
Bactericidal and Anti-biofilm Activity of the Retinoid Compound CD437 Against Enterococcus faecalis
Frontiers in Microbiology, 2019 Enterococcus faecalis (E. faecalis), a biofilm-forming pathogen, causes nosocomial infections. In recent years, drug resistance by enterococci has become increasingly severe due to widespread antibiotic abuse.
Fang Tan +6 more
doaj +1 more source
YAKUGAKU ZASSHI, 1996 Retinoids, retinoic acid and its bioisosters, regulate many biological functions such as cell differentiation, proliferation and embryonic development in vertebrates, through binding to and activating their specific nuclear receptors. There are two classes of nuclear receptors for retinoids, retinoic acid receptors (RAR alpha, beta, gamma) and retinoid
H, Umemiya +4 more
openaire +3 more sources
BMC Cancer, 2018 For decades, retinoids and their synthetic derivatives have been well established anticancer treatments due to their ability to regulate cell growth and induce cell differentiation and apoptosis. Many studies have reported the promising role of retinoids
Viera Dobrotkova +4 more
semanticscholar +1 more source
Assessing the Safety and Efficacy of Trifarotene in the Treatment of Acne Vulgaris
Therapeutics and Clinical Risk Management, 2021 Caitlin M Brumfiel,1 Meera H Patel,2 Katheryn A Bell,1 Michael A Cardis3 1Georgetown University School of Medicine, Washington, DC, USA; 2Creighton University School of Medicine, Phoenix Regional Campus, Phoenix, AZ, USA; 3MedStar Washington Hospital ...
Brumfiel CM +3 more
doaj
Trifarotene: A Current Review and Perspectives in Dermatology
Biomedicines, 2021 Retinoids have numerous applications in inflammatory, dyskeratotic, and oncohematology diseases. Retinoids have now reached the fourth generation, progressively reducing toxicity whilst increasing their efficacy.
Terenzio Cosio +7 more
doaj +1 more source