Results 21 to 30 of about 121,956 (356)

Bactericidal and Anti-biofilm Activity of the Retinoid Compound CD437 Against Enterococcus faecalis

Frontiers in Microbiology, 2019
Enterococcus faecalis (E. faecalis), a biofilm-forming pathogen, causes nosocomial infections. In recent years, drug resistance by enterococci has become increasingly severe due to widespread antibiotic abuse.
Fang Tan, Pengfei She, Linying Zhou, Yiqing Liu, Lihua Chen, Zhen Luo, Yong Wu   +6 more
doaj   +1 more source

Vitamin A affects flatfish development in a thyroid hormone signaling and metamorphic stage dependent manner [PDF]

, 2017
Vitamin A (VA) and retinoid derivatives are known morphogens controlling vertebrate development. Despite the research effort conducted during the last decade, the precise mechanism of how VA induces post-natal bone changes, and particularly those ...
Balmer, Basset, Boglino, Boglione, Boglione, Bustin, Campinho, Cardeira, Cañavate, Fernández, Fernández, Fernández, Fernández, Fernández, Fernández, Fernández, Fernández-Díaz, Fiaz, Folch, Fröhlich, Funkenstein, Gavaia, Gavaia, Geffen, Georga, Germain, Germain, Giménez, Gogakos, Gomes, Haga, Haga, Hamade, Hamre, Infante, Karsenty, Kilkenny, Klymkowsky, Laue, Le Du, Li, Li, Lie, Lie, Manchado, Manchado, Mazurais, Morais, Moren, Mühlbauer, Negm, Negm, Okada, Oliveira, Ortiz-Delgado, Pfaffl, Pinto, Pittman, Richard, Ronnestad, Ross, Shao, Silva, Sire, Spoorendonk, Sternberg, Takeuchi, Takeuchi, Targovnik, Totland, van der Meeren, Villeneuve, Wagemans, Witten   +73 more
core   +3 more sources

Traffic lights for retinoids in oncology: molecular markers of retinoid resistance and sensitivity and their use in the management of cancer differentiation therapy

BMC Cancer, 2018
For decades, retinoids and their synthetic derivatives have been well established anticancer treatments due to their ability to regulate cell growth and induce cell differentiation and apoptosis. Many studies have reported the promising role of retinoids
Viera Dobrotkova, P. Chlapek, P. Mazánek, J. Štěrba, R. Veselska   +4 more
semanticscholar   +1 more source

Metabolic interactions between vitamin A and conjugated linoleic acid [PDF]

, 2014
Lipid-soluble molecules share several aspects of their physiology due to their common adaptations to a hydrophilic environment, and may interact to regulate their action in a tissue-specific manner.
BANNI, SEBASTIANO, Belury, MA, CARTA, GIANFRANCA, Cordeddu, L, Giordano, E, MURRU, MARIA ELISABETTA, Ortiz, B, Quadro, L   +7 more
core   +2 more sources

The retina visual cycle is driven by cis retinol oxidation in the outer segments of cones [PDF]

, 2017
Vertebrate rod and cone photoreceptors require continuous supply of chromophore for regenerating their visual pigments after photoactivation. Cones, which mediate our daytime vision, demand a particularly rapid supply of 11-cis retinal chromophore in ...
Cornwall, M. Carter, Frederiksen, Rikard, Kefalov, Vladimir J, Sato, Shinya   +3 more
core   +2 more sources

Effect of Hyperoxia on Retinoid Metabolism and Retinoid Receptor Expression in the Lungs of Newborn Mice. [PDF]

PLoS ONE, 2015
Preterm newborns that receive oxygen therapy often develop bronchopulmonary dysplasia (BPD), which is abnormal lung development characterized by impaired alveologenesis.
Hsing-Jin Chen, Bor-Luen Chiang
doaj   +1 more source

Retinoid X receptor activation reverses age-related deficiencies in myelin debris phagocytosis and remyelination.

Brain : a journal of neurology, 2015
The efficiency of central nervous system remyelination declines with age. This is in part due to an age-associated decline in the phagocytic removal of myelin debris, which contains inhibitors of oligodendrocyte progenitor cell differentiation.
M. Natrajan, A. G. de la Fuente, A. Crawford, E. Linehan, Vanessa Núñez, Kory R. Johnson, Tianxia Wu, D. Fitzgerald, M. Ricote, B. Bielekova, R. Franklin   +10 more
semanticscholar   +1 more source

Differential effects of steroids and retinoids on bovine myelopoiesis in vitro [PDF]

, 2004
Pregnancy and parturition are associated with physiological changes caused by steroid hormones. Alterations in number, maturity, and function of polymorphonuclear leukocytes observed in dairy cows at parturition suggest a common causative relationship ...
Burvenich, Christian, Duchateau, Luc, Meyer, Evelyne, VAN MERRIS, V   +3 more
core   +1 more source

Synthetic Retinoid Kills Drug‐Resistant Cancer Stem Cells via Inducing RARγ‐Translocation‐Mediated Tension Reduction and Chromatin Decondensation

Advanced Science, 2022
A recently developed synthetic retinoid abrogates proliferation and induces apoptosis of drug‐resistant malignant‐cancer‐stem‐cell‐like cells. However, the underlying mechanisms of how the synthetic retinoid induces cancer‐stem‐cell‐like cell tumor ...
Yao Zhang, Qi Dong, Quanlin An, Chumei Zhang, Erfan Mohagheghian, Bing Niu, Feng Qi, Fuxiang Wei, Sihan Chen, Xinman Chen, Anqi Wang, Xin Cao, Ning Wang, Junwei Chen   +13 more
doaj   +1 more source

Retinoids and Retinoid Receptors in Teratogenesis* [PDF]

Congenital Anomalies, 1995
AbstractThere is overwhelming evidence that vitamin A (retinol), presumably through its metabolite retinoic acid, participates in organogenesis at several stages and sites during normal development. Besides the important role of retinol and retinoic acid (RA) as micronutrients in growth and development, these retinoids and their synthetic analogs are ...
openaire   +2 more sources