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Conjugated linoleic acid (CLA) is a polyunsaturated fatty acid obtained from ruminant products. Previous studies in rats and pigs showed that a dietary equimolar mixture of c9,t11 and t10,c12 CLA isomers induces changes in serum and tissue levels of ...
Berenice Ortiz +5 more
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Dietary Vitamin A Impacts Refractory Telogen
Hair follicles cycle through periods of growth (anagen), regression (catagen), rest (telogen), and release (exogen). Telogen is further divided into refractory and competent telogen based on expression of bone morphogenetic protein 4 (BMP4) and wingless ...
Liye Suo +6 more
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Alcohol and retinoid metabolism [PDF]
See article on page 825 The complex interactions between the metabolism of retinoids and ethanol have been reported for a long time. Clinically, chronic ethanol consumption leads to vitamin A deficiency but also to enhanced toxicity of vitamin A and beta-carotene when supplemented.
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All-trans and 9-cis retinoic acids function as ligands for retinoic acid receptors (RARs and RXRs), which are ligand-dependent transcription factors and play important roles in development and cellular differentiation.
Helene Brodeur +3 more
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High‐sensitivity chemical imaging offers a window to decipher the molecular orchestra inside a living system. Based on vibrational fingerprint signatures, coherent Raman scattering microscopy provides a label‐free approach to map biomolecules and drug ...
Minghua Zhuge +10 more
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Retinoid Metabolism and Mode of Action
Vitamin A and its derivaties (retinoids) are necessary for the maintenance of normal phenotypic expression. An attempt at understanding the biochemical role of vitamin A had led to the demonstration of a new pathway for retinol. In this pathway, vitamin A is phosphorylated to retinylphosphate (RP), which is then glycosylated to retinylphosphatemannose (
L. M. De Luca +6 more
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Retinoids are a group of vitamin A-related chemicals that are essential to chordate mammals. They regulate a number of basic processes, including embryogenesis and vision.
Vinesh Dhokia, Salvador Macip
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Chylomicron remnant-vitamin A metabolism by the human hepatoma cell line HepG2.
The binding and metabolism of [3H]vitamin A-containing chylomicron (CM) remnants by the human hepatoma cell line HepG2 were studied. Mesenteric lymph chylomicrons were collected from [3H]retinol-fed rats and incubated with lipoprotein lipase to obtain CM
C M Lenich, A C Ross
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Retinoids can act as transcriptional regulators to regulate cell proliferation, differentiation, and other processes. Here, the authors show that uncompromised vitamin A (retinoid) metabolism and signaling in alveolar lipofibroblasts, endothelial and ...
Igor O. Shmarakov +5 more
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Systemic Organ Involvement and Retinoid Signaling Disorder in COVID-19
Although more than a year has passed since the COVID-19 outbreak, the pathogenesis of the disease has not yet been clearly explained. The way to develop effective vaccines and drugs against the disease depends on a clear elucidation of the pathogenesis ...
Aziz Rodan Sarohan
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