Results 11 to 20 of about 905,398 (250)
Retinoid metabolism in the rat small intestine [PDF]
British Journal of Nutrition, 2005 Vitamin A (retinol) is essential for epithelial cell growth, differentiation and proliferation. The absorption of retinol occurs in the small intestine, and the metabolism of this vitamin is not well studied in this organ. The intestinal epithelium has a high rate of cell proliferation and differentiation, and the present study looked at the level of ...
Simmy, Thomas +2 more
openaire +3 more sources
STRA6 and Placental Retinoid Metabolism in Gestational Diabetes Mellitus. [PDF]
J Pers Med, 2021 Background: Recent reports indicate the potential role of the stimulated by retinoic acid 6 (STRA6) protein in developing insulin resistance. The study’s objective was to assess placental STRA6 expression and staining pattern in human pregnancy ...
Fruscalzo A +7 more
europepmc +3 more sources
Cellular retinoid binding-proteins, CRBP, CRABP, FABP5: Effects on retinoid metabolism, function and related diseases. [PDF]
Pharmacol Ther, 2017 Cellular binding-proteins (BP), including CRBP1, CRBP2, CRABP1, CRABP2, and FABP5, shepherd the poorly aqueous soluble retinoids during uptake, metabolism and function.
Napoli JL.
europepmc +2 more sources
Retinoids and the metabolic syndrome [PDF]
Expert Review of Endocrinology & Metabolism, 2008 The metabolic syndrome comprises a number of metabolic disorders, including abdominal obesity, dyslipidemia, hypertension and impaired fasting glucose, that contribute to increased cardiovascular d...
Sheila M, O'Byrne, William S, Blaner
openaire +2 more sources
Hepatology, EarlyView., 2022 Graphical summary of obesity‐induced NASH progression by LCN2 targeted to HSC activation. Abstract Background and Aims In obesity and type 2 diabetes mellitus, leptin promotes insulin resistance and contributes to the progression of NASH via activation of hepatic stellate cells (HSCs).
Kyung Eun Kim +12 more
wiley +1 more source
Retinoid homeostasis in major depressive disorder
Translational Psychiatry, 2023 The small, hormone-like molecule retinoic acid (RA) is a vital regulator in several neurobiological processes that are affected in depression. Next to its involvement in dopaminergic signal transduction, neuroinflammation, and neuroendocrine regulation ...
Lisa Rebecca Otto +5 more
doaj +1 more source
Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis
Hepatology, EarlyView., 2022 Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis. Abstract Background and Aims Nucleotide‐binding oligomerization domain‐like receptor‐family pyrin domain‐containing 3 (NLRP3) inflammasome activation has been shown to result in liver fibrosis.
Jana Knorr +19 more
wiley +1 more source
Neural Development, 2020 Background Neural tube defects (NTDs) are failure of neural tube closure, which includes multiple central nervous system phenotypes. More than 300 mouse mutant strains exhibits NTDs phenotypes and give us some clues to establish association between ...
Jizhen Zou +6 more
doaj +1 more source
Clinical Epigenetics, 2023 Background MTR gene encodes the cytoplasmic enzyme methionine synthase, which plays a pivotal role in the methionine cycle of one-carbon metabolism.
Karim Matmat +14 more
doaj +1 more source
Skin Health and Disease, 2021 Background Retinoid‐based therapies are commonly used in the treatment of disorders of keratinization and other skin disorders but can result in non‐specific effects and adverse reactions.
J.G.S. Veit +9 more
doaj +1 more source