Results 151 to 160 of about 1,703 (209)
There is no straightforward method to visualize the intracellular distribution of nuclear receptors, such as retinoid X receptors (RXRs), which are trafficked between the cytosol and nucleus.
Mayu Kawasaki (7320929) +6 more
core +1 more source
ABSTRACT Background Aging skin is a universal complaint among diverse patient populations. It encompasses physiologic changes to the skin, such as skin laxity, dyspigmentation, fine lines, and wrinkles. However, different populations may show different signs of aged skin.
Zill‐e‐human Khan +5 more
wiley +1 more source
Recent Polygenic Adaptation in Heavily Fished Malawi Cichlids
ABSTRACT Intense fishing pressure can drive rapid evolution in wild populations, yet the underlying genomic mechanisms often remain elusive. Here, we investigate the genomic consequences of five decades of intense harvesting on the cichlid fish Copadichromis mloto in Lake Malombe, Malawi.
Alexander Hooft van Huysduynen +5 more
wiley +1 more source
Retinol‐Loaded Mannosylerythritol Lipid Nanoliposome for Enhanced Human Skin Penetration
ABSTRACT Background Functional cosmetic materials with anti‐aging properties, such as wrinkle reduction, often struggle to penetrate the skin's stratum corneum (skin barrier). Therefore, to exert anti‐aging effects, these materials must pass through the skin barrier and reach fibroblasts in the dermal layer.
Han‐woong Park +3 more
wiley +1 more source
This study investigates the role of the vision gene RGR using novel dual knockout zebrafish models. The loss of rgra and rgrb results in zebrafish larvae having reduced visual function and altered retinoid profiles under light but not dark conditions. The OKR phenotype is enhanced under higher light intensities.
Grace Ruddin +13 more
wiley +1 more source
Liver X Receptor and Retinoid X Receptor in Cartilage Development and Homeostasis [PDF]
Osteoarthritis (OA) is a heterogeneous and multifactorial degenerative disease characterized by cartilage degradation in the joint. Available treatment options target symptoms but do not address the underlying issue of joint tissue degeneration. A better understanding of the molecular mechanisms maintaining cartilage health is essential for developing ...
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