Results 151 to 160 of about 23,550 (202)
Role of the retinoid X receptor-peroxisome proliferator-activated receptor-γ axis in adolescent attention-deficit hyperactivity disorder. [PDF]
Hsu JW +4 more
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Th,-e mechanistic insights into the application of retinoids and possible adjunct therapeutic treatment to androgenic alopecia. [PDF]
Irfan H +4 more
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A Comprehensive Review: The Bidirectional Role of Sebum in Skin Health. [PDF]
Li D +7 more
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The role of RARG in solid tumor progression and therapeutic potential. [PDF]
Guo S, Han H, Ding B, Zhang W, Qin L.
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Retinoid X receptors and retinoid response in neuroblastoma cells
Journal of Cellular Biochemistry, 2002AbstractRetinoic acid (RA) modulates differentiation and apoptosis of neural cells via RA receptors (RARs) and retinoid X receptors (RXRs). Neuroblastoma cells are potentially useful models for elucidating the molecular mechanisms of RA in neural cells, and responses to different isomers of RA have been interpreted in terms of differential homo‐ and ...
Rana +7 more
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Retinoids Selective for Retinoid X Receptor Response Pathways
Science, 1992Retinoids have a broad spectrum of biological activities and are useful therapeutic agents. Their physiological activities are mediated by two types of receptors, the retinoic acid receptors (RARs) and the retinoid X receptors (RXRs). RARs, as well as several related receptors, require heterodimerization with RXRs for effective DNA binding
J M, Lehmann +7 more
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Synthesis of Novel Retinoid X Receptor-Selective Retinoids
The Journal of Organic Chemistry, 2001Retinoids 1-5 have been identified as potent RXR agonists for evaluation in the treatment of non-insulin-dependent (type II) diabetes mellitus (NIDDM). Highly convergent syntheses of 1-5 have been developed. The core tetrahydronaphthalene 7, employed in the synthesis of 1 and 2, was prepared in 98% yield using an AlCl(3)-catalyzed (0.03 equiv) Friedel ...
M M, Faul +4 more
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