Results 161 to 170 of about 1,703 (209)
Role of PPARs and Retinoid X Receptors in the Regulation of Lung Maturation and Development
PPAR Research, 2007 Thomas J. Mariani, Dawn M. Simon
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Characterization of the locust retinoid X receptors
, 2007 The retinoid X receptor (RXR) participates in a multitude of nuclear receptor signaling pathways and is induced by its highly sought-after cognate ligand, 9-cis-retinoic acid (9-cis-RA). In flies and moths, molting is mediated by the ecdysone receptor that consists of a heterodimer comprising the ecdysone receptor monomer (EcR) and the invertebrate RXR
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Retinoid-X Receptor Action and Disruption in Development
Developmental BiologyBrenda J. Mengeling, J. David Furlow
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Differential expression of retinoid receptors in the adult mouse central nervous system
Neuroscience, 1999 International audienceThe immunocytochemical distribution of retinoid receptors has been analysed in the mouse adult central nervous system. All retinoic acid receptors (alpha, beta and gamma) and retinoid X receptors (alpha, beta and gamma) were ...
Wojciech Krezel +2 more
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Retinoid receptors in ovarian cancer: expression and prognosis [PDF]
Annals of Oncology, 2005 BACKGROUND Ovarian cancer is frequently lethal despite aggressive multimodal therapy, and new therapies are therefore needed. Retinoids are potential candidate drugs: they prevent the development of ovarian carcinoma and enhance the efficacy of ...
Meike Körner +2 more
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Active repression by unliganded retinoid receptors in development [PDF]
Journal of Cell Biology, 2003 The retinoid receptors have major roles throughout development, even in the absence of ligand. Here, we summarize an emerging theme whereby gene repression, mediated by unliganded retinoid receptors, can dictate cell fate.
Andrea D Weston +2 more
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Retinoid X receptors and retinoid response in neuroblastoma cells
Journal of Cellular Biochemistry, 2002AbstractRetinoic acid (RA) modulates differentiation and apoptosis of neural cells via RA receptors (RARs) and retinoid X receptors (RXRs). Neuroblastoma cells are potentially useful models for elucidating the molecular mechanisms of RA in neural cells, and responses to different isomers of RA have been interpreted in terms of differential homo‐ and ...
Rana +7 more
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Neuroscience, 2004 Peroxisome proliferator-activated and retinoid X receptors (PPARs and RXRs) are transcription factors belonging to the steroid hormone receptor superfamily.
Maria Paola Ceru
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Retinoids Selective for Retinoid X Receptor Response Pathways
Science, 1992Retinoids have a broad spectrum of biological activities and are useful therapeutic agents. Their physiological activities are mediated by two types of receptors, the retinoic acid receptors (RARs) and the retinoid X receptors (RXRs). RARs, as well as several related receptors, require heterodimerization with RXRs for effective DNA binding
J M, Lehmann +7 more
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