Results 101 to 110 of about 932,750 (311)

Review Article: Renal Safety Profiles of Tenofovir Alafenamide, Tenofovir Disoproxil Fumarate, and Entecavir for the Treatment of Chronic Hepatitis B Infection—General and Special Populations

Alimentary Pharmacology &Therapeutics, EarlyView.
Current first‐line NUCs show comparable renal safety profiles in CHB patients with no or mild kidney dysfunction, with growing evidence that favours TAF. Future prospective studies are needed to validate these findings, and more research should focus on CHB patients with diabetes mellitus who are at risk of CKD.
Lung‐Yi Mak, Tsung‐Hui Hu, Desmond Y. H. Yap   +2 more
wiley   +1 more source

Changes in Serum Levels of Retinol Binding Protein 4, Glucose and Insulin in Adaptation to Nettle Supplementation and Combination Training in Overweight Men With Type 2 Diabetes [PDF]

, 2021
Vahid Tayid, Aziz Zinivand Lorestani, Mahbanoo Ghaderi, Hadi Gharani, Yaser Mehdizadeh, Marzieh Havasi   +5 more
openalex   +1 more source

SRP-35, a newly identified protein of the skeletal muscle sarcoplasmic reticulum, is a retinol dehydrogenase [PDF]

, 2011
In the present study we provide evidence that SRP-35, a protein we identified in rabbit skeletal muscle sarcoplasmic reticulum, is an all-trans-retinol dehydrogenase.
Bergamelli, Leda, Csernoch, Laszlo, Mosca, Barbara, Oberhauser, Vitus, Ronjat, Michel, Szentesi, Peter, Thurnheer, Raphael, Treves, Susan, Voltan, Rebecca, Vukcevic, Mirko, Zorzato, Francesco   +10 more
core   +1 more source

A supramolecular assembly of cone‐specific G‐protein and cryptochrome 4a on lipid bilayer

The FEBS Journal, EarlyView.
Immobilized phospholipid bilayers on a sensor chip surface serve as membrane platform to investigate critical protein–lipid and protein–protein interaction processes by surface plasmon resonance. The putative magnetoreceptor cryptochrome 4a and the myristoylated cone‐specific G‐protein α‐subunit (Gtα) bind with high affinity to immobilized lipid ...
Ümmügülsüm Güzelsoy‐Flügge, Srđan Vujinović, Alexander Scholten, Karl‐Wilhelm Koch   +3 more
wiley   +1 more source

Application of retinol to human skin in vivo induces epidermal hyperplasia and cellular retinoid binding proteins characteristic of retinoic acid but without measurable retinoic acid levels or irritation.

Journal of Investigative Dermatology, 1995
We investigated the clinical, histologic, and molecular responses of normal human skin to all-trans-retinol (ROL) application, compared to those induced by topical all-trans-retinoic acid (RA), and measured ROL-derived metabolites. Up to 1.6% ROL, 0.025%
S. Kang, E. Duell, G. Fisher, S. Datta, Z. Wang, A. Reddy, A. Tavakkol, J. Yi, C. Griffiths, James T. Elder   +9 more
semanticscholar   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth, Zhou Yuxi, Yong Jiawen, Wang Lei, Ruf Sabine, Meyle Joerg   +5 more
wiley   +1 more source

Retinol and retinol binding protein 4 levels and COVID-19: a Mendelian randomization study

BMC Pulmonary Medicine
Background The Corona Virus Disease 2019 (COVID-19) pandemic has struck globally. Whether the related proteins of retinoic acid (RA) signaling pathway are causally associated with the risk of COVID-19 remains unestablished.
Haixia Wang, Zhiyun Zhang, Li Xie, Kongli Lu, Shuyi Zhang, Shunpeng Xing   +5 more
doaj   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

Analysis of the interaction of calcitriol with the disulfide isomerase ERp57 [PDF]

, 2016
Calcitriol, the active form of vitamin D3, can regulate the gene expression through the binding to the nuclear receptor VDR, but it can also display nongenomic actions, acting through a membrane- associated receptor, which has been discovered as the ...
Altieri, Fabio, Cervoni, Laura, Chichiarelli, Silvia, Eufemi, Margherita, Gaucci, Elisa, Grillo, Caterina, Nittari, Giulio, Raimondo, Domenico   +7 more
core   +1 more source

Electrophoretic patterns of proteinuria in dogs with Cushing’s syndrome

Journal of Small Animal Practice, EarlyView.
Objectives To describe the electrophoretic pattern of proteinuria in dogs with naturally occurring Cushing’s syndrome. We hypothesised that urine protein electrophoresis in dogs with spontaneous Cushing’s syndrome will reveal glomerular proteinuria. We also hypothesised that the severity of proteinuria would decrease during treatment with trilostane ...
J. Milenkovic, T. Francey, A. Schweighauser, J. Howard, S. Kittl, M. Campos   +5 more
wiley   +1 more source