Results 111 to 120 of about 41,997 (234)

Toll Like Receptor 4: A Potential Link Between Obesity and Metabolic Diseases

open access: yesObesity Reviews, Volume 27, Issue 8, August 2026.
ABSTRACT Epidemiological evidence shows that obesity increases the risk of developing metabolic diseases. Nevertheless, the mechanisms behind this connection remain underappreciated. The substantial impact of these disorders on global health has led to extensive research efforts aimed at identifying the pathophysiological links between them.
Ghadeer Alhamar   +4 more
wiley   +1 more source

Natural History of Chronic Kidney Disease in Sickle Cell Disease

open access: yesAmerican Journal of Hematology, Volume 101, Issue 7, Page 1456-1477, July 2026.
ABSTRACT Kidney complications, referred to as nephropathy, develop early in sickle cell disease (SCD). In addition to its known morbidity, abundant data show that chronic kidney disease (CKD) is associated with an increased mortality risk in SCD. Increasing evidence suggests that the natural history of SCD nephropathy is progressive. Initial glomerular
Kenneth I. Ataga
wiley   +1 more source

Caenorhabditis elegans and Drosophila melanogaster as Model Organisms in Biofactor Research

open access: yesBioFactors, Volume 52, Issue 4, July/August 2026.
This review presents Caenorhabditis elegans and Drosophila melanogaster as powerful and ethically sound invertebrate model organisms that can be used to investigate nutritional science questions relating to biofactors. Such nutritional phenotyping studies can bridge the gap between in vitro studies and in vivo research in mammals.
Kai Lüersen   +2 more
wiley   +1 more source

CCT7 Expression Affects the Prognosis of Lung Adenocarcinoma

open access: yesCancer Reports, Volume 9, Issue 7, July 2026.
ABSTRACT Background CCT7 is a chaperonin containing tailless complex polypeptide 1 subunit. The study focused on investigating its prognostic significance for lung adenocarcinoma (LUAD). Methods CCT7 expression in LUAD and matched non‐carcinoma lung samples was examined via TCGA database. Besides, we utilized the GEO database and RT‐qPCR for validating
Yue Li   +8 more
wiley   +1 more source

Retinol, Carotenoid, and Tocopherol Intake and Status, and the Risk of Islet Autoimmunity and Type 1 Diabetes: The Environmental Determinants of Diabetes in the Young Study

open access: yesDiabetes/Metabolism Research and Reviews, Volume 42, Issue 5, July 2026.
ABSTRACT Aims To study the associations of dietary intake of A and E vitamins, as well as plasma retinols, carotenoids, and tocopherols in relation to development of islet autoimmunity and progression to T1D. Materials and Methods The Environmental Determinants of Diabetes in the Young (TEDDY) Study followed 7659 newborns with genetic susceptibility to
Leena Hakola   +18 more
wiley   +1 more source

Therapeutic Potential of Berberis vulgaris in Modulating Metabolic Syndrome Biomarkers: Mechanistic Insights and Functional Food Implications

open access: yesFood Frontiers, Volume 7, Issue 4, July 2026.
ABSTRACT Barberry (Berberis vulgaris) has emerged as a promising functional food candidate for the management of metabolic syndrome due to its diverse bioactive constituents, particularly berberine. This review synthesizes current experimental and clinical evidence regarding its effects on glycemic control, lipid metabolism, blood pressure regulation ...
Fakhar Shahid   +5 more
wiley   +1 more source

Steviol Glycosides (E960) From Stevia rebaudiana: Technological Innovations, Safety Assessment, Regulatory Aspects and Their Role in Sustainable Food Systems

open access: yesFood Science &Nutrition, Volume 14, Issue 7, July 2026.
Steviol Glycosides (E960) from Stevia rebaudiana: Technological Innovations, Safety Assessment, Regulatory Aspects and their Role in Sustainable Food Systems. ABSTRACT Stevia (Stevia rebaudiana Bertoni) is a small perennial herb widely recognized as a natural sweetener.
Aswin Sakthivel Manoharan   +1 more
wiley   +1 more source

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