Results 101 to 110 of about 55,898 (311)

Self-rated health in middle-aged and elderly Chinese : distribution, determinants and associations with cardio-metabolic risk factors [PDF]

open access: yes, 2009
Background: Self-rated health (SRH) has been demonstrated to be an accurate reflection of a person's health and a valid predictor of incident mortality and chronic morbidity.
A Pan   +40 more
core   +3 more sources

Identification of genetically predicted protein biomarkers and drug targets for prostate cancer via Mendelian randomization

open access: yesVIEW, EarlyView.
Prostate cancer, a leading cause of cancer in men globally, urgently requires improved diagnostic and treatment strategies. This study analyzed large genetic datasets and identified five key proteins (THBD, DST, IFI27L2, OSBPL10, PPP1R14A) that either increase or decrease cancer risk, while also exploring their roles in immune response and potential ...
Maoping Cai   +11 more
wiley   +1 more source

Prospective Relation of Circulating Adipokines to Incident Metabolic Syndrome: The Framingham Heart Study

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundAdipokines are elaborated by adipose tissue and are associated with glycemic, lipid, and vascular traits. We hypothesized that in a cross‐sectional analysis circulating adipokines are altered among subsets of obesity stratified by presence ...
Justin P. Zachariah   +6 more
doaj   +1 more source

Transthyretin levels in the vitreous correlate with change in visual acuity after vitrectomy [PDF]

open access: yes, 2009
Background/aim: Little is known about biochemical markers related to change in visual acuity after vitrectomy. The potential use of transthyretin (TTR), a carrier of the retinol/retinol-binding protein, as a biochemical marker protein, was investigated ...
De Letter, Els   +7 more
core   +3 more sources

An engineered epididymal cell line provides a sustainable source of functional extracellular vesicles for in vitro sperm preservation: A multi‐omics and functional study

open access: yesVIEW, EarlyView.
ABSTRACT This study investigated the function of epididymal extracellular vesicles (EVs) in overcoming sperm post‐testicular modification deficiencies. Although EVs derived from the epididymis play a crucial role in intercellular communication and molecular exchange, there is limited research addressing how EVs released by in vitro cultured epididymal ...
Long Li   +10 more
wiley   +1 more source

Serum retinol-binding protein 4 and the risk of ischemic stroke in Egyptian patients with hypothyroidism

open access: yesThe Egyptian Journal of Internal Medicine, 2019
Objective Ischemic stroke (IS) is one of the major causes of disability and death worldwide. Effective prevention remains the best approach to reduce the burden of stroke.
Nearmeen M Rashad   +5 more
doaj   +1 more source

Examination of Fluconazole-Induced Alopecia in an Animal Model and Human Cohort. [PDF]

open access: yes, 2019
Fluconazole-induced alopecia is a significant problem for patients receiving long-term therapy. We evaluated the hair cycle changes of fluconazole in a rat model and investigated potential molecular mechanisms.
Aaron, Phylicia A   +15 more
core  

A supramolecular assembly of cone‐specific G‐protein and cryptochrome 4a on lipid bilayer

open access: yesThe FEBS Journal, EarlyView.
Immobilized phospholipid bilayers on a sensor chip surface serve as membrane platform to investigate critical protein–lipid and protein–protein interaction processes by surface plasmon resonance. The putative magnetoreceptor cryptochrome 4a and the myristoylated cone‐specific G‐protein α‐subunit (Gtα) bind with high affinity to immobilized lipid ...
Ümmügülsüm Güzelsoy‐Flügge   +3 more
wiley   +1 more source

Cellular retinol-binding protein-1 expression in endometrial stromal cells: physiopathological and diagnostic implications [PDF]

open access: yes, 2004
Cellular retinol-binding protein-1 (CRBP-1) contributes to the maintenance of the differentiated state of the endometrium through retinol bioavailability regulation.
Ciucci, A   +7 more
core   +1 more source

Bioretinoids from microalgae: Boosting retinol performance and tolerability

open access: yesInternational Journal of Cosmetic Science, EarlyView.
A novel microalgae‐derived bioretinoid (MBR) enhances skin regeneration, improves pigmentation, and reduces signs of ageing more effectively than bakuchiol and comparably to retinol—without the irritation. MBR also synergizes with retinol, boosting hydration and safety. A powerful, gentle alternative for advanced skincare.
Silvia Sánchez‐Díez   +3 more
wiley   +1 more source

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