Results 31 to 40 of about 3,830 (170)

An LC/MS/MS method for stable isotope dilution studies of β-carotene bioavailability, bioconversion, and vitamin A status in humans[S]

Journal of Lipid Research, 2014
Isotope dilution is currently the most accurate technique in humans to determine vitamin A status and bioavailability/bioconversion of provitamin A carotenoids such as β-carotene.
Anthony Oxley, Philip Berry, Gordon A. Taylor, Joseph Cowell, Michael J. Hall, John Hesketh, Georg Lietz, Alan V. Boddy   +7 more
doaj   +1 more source

An LC/MS method for d8-β-carotene and d4-retinyl esters: β-carotene absorption and its conversion to vitamin A in humans

Journal of Lipid Research, 2012
The intestinal absorption and metabolism of β-carotene is of vital importance in humans, especially in populations that obtain the majority of their vitamin A from provitamin A carotenoids.
Matthew K. Fleshman, Ken M. Riedl, Janet A. Novotny, Steven J. Schwartz, Earl H. Harrison   +4 more
doaj   +1 more source

Acyl CoA:retinol acyltransferase in rat small intestine: its activity and some properties of the enzymic reaction.

Journal of Lipid Research, 1982
The present study was conducted to examine whether the intestinal esterification of retinol could be due to a microsomal acyl-CoA transferase. When the 'microsomal fraction' of rat mucosa was incubated with [3H]retinol and palmitoyl-CoA or oleoyl-CoA ...
P Helgerud, L B Petersen, K R Norum
doaj   +1 more source

Histological manifestations of vitamin A toxicity in the liver

Histopathology, EarlyView.
Analysing clinicopathological data from 1960 to 2025, this study characterizes the spectrum of liver injury associated with chronic vitamin A toxicity. Hepatic stellate cell hypertrophy/hyperplasia and sinusoidal fibrosis emerge as the predominant features, providing a morphological basis for diagnosing vitamin A hepatotoxicity.
Giorgio Cazzaniga, Georg Lietz, Dina G. Tiniakos   +2 more
wiley   +1 more source

Cell proliferation inhibition and alterations in retinol esterification induced by phytanic acid and docosahexaenoic acid

Journal of Lipid Research, 2007
We investigated the effects of two natural dietary retinoid X receptor (RXR) ligands, phytanic acid (PA) and docosahexaenoic acid (DHA), on proliferation and on the metabolism of retinol (vitamin A) in both cultured normal human prostate epithelial cells
Xiao-Han Tang, Moo-Jin Suh, Rong Li, Lorraine J. Gudas   +3 more
doaj   +1 more source

Targeted keratin repair: A plant‐based approach to hair strength and surface restoration

International Journal of Cosmetic Science, EarlyView.
Application of Avena strigosa seed extract may reinforce keratin bonding, restoring hair fibre integrity by promoting intramolecular interactions at damaged sites of keratin proteins. Abstract Objective Chemical and thermal stress disrupts the intramolecular and intermolecular interactions that stabilize hair keratin, leading to structural degradation ...
Emina Besic Gyenge, Loya Schoeffel, Stefan Hettwer, Andreas Bosch, Cosimo Kropp, Brigit Suter, Barbara Obermayer   +6 more
wiley   +1 more source

Long-term kinetic study of β-carotene, using accelerator mass spectrometry in an adult volunteer

Journal of Lipid Research, 2000
We present a sensitive tracer method, suitable for in vivo human research, that uses β-[14C]carotene coupled with accelerator mass spectrometry (AMS) detection.
Stephen R. Dueker, Yumei Lin, Bruce A. Buchholz, Phillip D. Schneider, Michael W. Lamé, H.J. Segall, John S. Vogel, Andrew J. Clifford   +7 more
doaj   +1 more source

Bakuchiol: From structural mimicry to systems‐level skin biology

International Journal of Cosmetic Science, EarlyView.
Convergent outcomes, divergent mechanisms: bakuchiol vs. retinol. Bakuchiol exhibits functional convergence with retinol in improving extracellular matrix integrity, epidermal differentiation and barrier function, while operating through distinct mechanisms.
Ratan K. Chaudhuri
wiley   +1 more source

Metabolism of retinol-binding protein and vitamin A during hypervitaminosis A in the rat

Journal of Lipid Research, 1975
Vitamin A is normally transported in plasma as retinol bound to a specific protein, retinol-binding protein (RBP). Detailed studies were conducted to examine the effects of excess vitamin A on the plasma concentration and metabolism of RBP, and to obtain
A.K. Mallia, J.E. Smith, D.W. Goodman
doaj   +1 more source

Retbindin Dynamically Redistributes to Preserve Retinal Flavin‐Dependent Homeostasis in Response to Riboflavin Availability and Circadian Demand

The FASEB Journal, Volume 40, Issue 18, 30 September 2026.
The retina is a part of the central nervous system, has remarkably high energy demands that require efficient retinal metabolism. Dysregulation of retinal metabolism disrupts energy supply and redox balance, leading to the pathogenesis of diverse retinal diseases. Riboflavin and its cofactors, flavin mononucleotide (FMN) and flavin adenine dinucleotide
Xue Zhao, Mustafa S. Makia, Gennadiy P. Moiseyev, Muna I. Naash, Muayyad R. Al‐Ubaidi   +4 more
wiley   +1 more source