Results 91 to 100 of about 16,020 (245)

A Family of Developmentally Excised DNA Elements in \u3cem\u3eTetrahymena\u3c/em\u3e is under Selective Pressure to Maintain an Open Reading Frame Encoding an Integrase-Like Protein [PDF]

open access: yes, 2000
Tlr1 is a member of a family of ~20-30 DNA elements that undergo developmentally regulated excision during formation of the macronucleus in the ciliated protozoan Tetrahymena.
Gershan, Jill A., Karrer, Kathleen M.
core   +1 more source

LTR-retrotransposons from Bdelloid rotifers capture additional ORFs shared between highly diverse retroelement types [PDF]

open access: yes, 2017
© The Author(s), 2017. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Viruses 9 (2017): 78, doi:10.3390/v9040078.Rotifers of the class Bdelloidea, microscopic freshwater ...
Arkhipova, Irina R.   +2 more
core   +1 more source

DNA methylation contributes to plant acclimation to naturally fluctuating light

open access: yesNew Phytologist, Volume 248, Issue 5, Page 2361-2375, December 2025.
Summary Plants in the natural environment experience continuous dynamic changes in light intensity. Here, we exposed Arabidopsis thaliana plants to naturally fluctuating light (FL) regimes alongside traditional square light (SQ) regimes such as those often found in control environment growth chambers.
Robyn A. Emmerson   +5 more
wiley   +1 more source

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, Volume 599, Issue 21, Page 3012-3028, November 2025.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

The use of retrotransposon-based molecular markers to analyze genetic diversity [PDF]

open access: yes, 2011
Molecular markers play an essential role in all aspects of genetics, modern plant breeding, in human forensics, for map-based cloning of genes, ranging from the identification of genes responsible for desired traits to the management of backcrossing ...
Kalendar, Ruslan
core   +2 more sources

Long‐read sequencing reveals genomic and epigenomic variation in the dark genome of human Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 21, Issue 11, November 2025.
Abstract INTRODUCTION Faulty DNA repair and epigenetic regulation contribute to neurodegeneration in Alzheimer's disease. Long‐read sequencing enables analysis of “dark regions” that are difficult to study via traditional sequencing methodologies.
Paulino Ramirez   +8 more
wiley   +1 more source

Role of MicroRNAs and Retroelements in the Pathogenesis of Atherosclerosis

open access: yesАрхивъ внутренней медицины
Atherosclerosis is the leading cause of cardiovascular disease among adults. The incidence of atherosclerosis increases significantly with age, which indicates the possible influence of aging mechanisms on the development of the disease, including ...
R. N. Mustafin, E. A. Galieva
doaj   +1 more source

XMRV and Public Health: The Retroviral Genome Is Not a Suitable Template for Diagnostic PCR, and Its Association with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Appears Unreliable

open access: yesFrontiers in Public Health, 2017
A few years ago, a highly significant association between the xenotropic murine leukemia virus-related virus (XMRV) and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), a complex debilitating disease of poorly understood etiology and no ...
Simona Panelli   +7 more
doaj   +1 more source

A unique regulatory phase of DNA methylation in the early mammalian embryo [PDF]

open access: yes, 2011
DNA methylation is highly dynamic during mammalian embryogenesis. It is broadly accepted that the paternal genome is actively depleted of 5-methylcytosine at fertilization, followed by passive loss that reaches a minimum at the blastocyst stage. However,
Chan, Michelle Mei Wah   +6 more
core   +1 more source

Disrupting endogenous retroelements with a reverse transcriptase inhibitor alleviates DSS-induced colitis in mice [PDF]

open access: hybrid, 2023
Yifan Niu   +8 more
openalex   +1 more source

Home - About - Disclaimer - Privacy