Results 71 to 80 of about 474 (133)

The role of COVID-19 in modified cognitive functioning

Якутский медицинский журнал
SARS-CoV-2 virus impairs cognitive functions during illness and in long-term periods: from 3 months (in 44% of patients) to one year (in 16.2% - 63% of patients) after recovery.
R. N. Mustafin, A. V. Kazantseva, E. K. Khusnutdinova   +2 more
doaj   +1 more source

On the Origin and Evolutionary Relationships of the Reverse Transcriptases Associated With Type III CRISPR-Cas Systems

Frontiers in Microbiology, 2018
Reverse transcriptases (RTs) closely related to those encoded by group II introns but lacking the intron RNA structure have been found associated with type III clustered regularly interspaced short palindromic repeats (CRISPR)-Cas systems, a prokaryotic ...
Nicolás Toro, Francisco Martínez-Abarca, Alejandro González-Delgado, Mario Rodríguez Mestre   +3 more
doaj   +1 more source

Contribution of Mobile Group II Introns to Sinorhizobium meliloti Genome Evolution

Frontiers in Microbiology, 2018
Mobile group II introns are ribozymes and retroelements that probably originate from bacteria. Sinorhizobium meliloti, the nitrogen-fixing endosymbiont of legumes of genus Medicago, harbors a large number of these retroelements.
Nicolás Toro, Francisco Martínez-Abarca, María D. Molina-Sánchez, Fernando M. García-Rodríguez, Rafael Nisa-Martínez   +4 more
doaj   +1 more source

Targeted Variant Assessments of Human Endogenous Retroviral Regions in Whole Genome Sequencing Data Reveal Retroviral Variants Associated with Papillary Thyroid Cancer

Microorganisms
Papillary thyroid cancer (PTC) is one of the fastest-growing cancers worldwide, lacking established causal factors or validated early diagnostics. Human endogenous retroviruses (HERVs), comprising 8% of human genomes, have potential as PTC biomarkers due
Erik Stricker, Erin C. Peckham-Gregory, Stephen Y. Lai, Vlad C. Sandulache, Michael E. Scheurer   +4 more
doaj   +1 more source

Significant Improvement of Environmental DNA Assay by Targeting Retrotransposon Sequences Characteristic to Anguilla Eels

Environmental DNA
Environmental DNA (eDNA) analysis faces challenges regarding sensitivity and quantification accuracy, particularly in areas with low target species densities or during seasons when eDNA release decreases.
Itsuki T. Hirayama, Yuta Kunimasa, Aya Takeuchi, Toshifumi Minamoto   +3 more
doaj   +1 more source

Endogenous MOV10 inhibits the retrotransposition of endogenous retroelements but not the replication of exogenous retroviruses

Retrovirology, 2012
Background The identification of cellular factors that regulate the replication of exogenous viruses and endogenous mobile elements provides fundamental understanding of host-pathogen relationships.
Arjan-Odedra Shetal, Swanson Chad M, Sherer Nathan M, Wolinsky Steven M, Malim Michael H   +4 more
doaj   +1 more source

Diel expression dynamics in filamentous cyanobacteria

mBio
Filamentous cyanobacteria of the Nostocaceae family can differentiate into multicellular forms to adapt to environmental stresses, and members can establish symbiosis with various embryophytes.
Sarah J. Kennedy, Douglas D. Risser, Blair G. Paul   +2 more
doaj   +1 more source

Role of Retroelements in Frontotemporal Dementia Development

Frontiers in Bioscience-Scholar
Frontotemporal dementia (FTD) develops in proteinopathies involving TDP-43 (transactive response DNA-binding protein 43 kDa), tau, and FUS (fused in sarcoma) proteins, which possess antiviral properties and exert inhibitory effects on human transposable ...
Rustam Nailevich Mustafin
doaj   +1 more source

Impact of viruses and retrotransposons on genetic instability and aging

Инфекция и иммунитет
Preventive medicine holds significant promise for delaying and even preventing dangerous age-related pathologies. Advances in vaccine development, new preventive medications, cardiovascular implants and early diagnostic tools has increased life ...
Elena V. Lysakova, Marina Y. Burak, Maxim B. Navrotsky, Stanislav A. Rybtsov   +3 more
doaj   +1 more source

Involvement of transposable elements in Alzheimer’s disease pathogenesis

Вавиловский журнал генетики и селекции
Alzheimer’s disease affects an average of 5 % of the population with a significant increase in prevalence with age, suggesting that the same mechanisms that underlie aging may influence this pathology.
R. N. Mustafin, E. K. Khusnutdinova
doaj   +1 more source