Results 101 to 110 of about 16,020 (245)

Participation of retroelements in chromoanagenesis in cancer development

open access: yesСибирский онкологический журнал
Purpose of the study: to determine the role of retroelements in chromoanagenesis mechanisms in cancer etiopathogenesis.Material and Methods. The search for relevant sources was carried out in the Scopus, Web of Science, PubMed, Elibrary systems ...
R. N. Mustafin
doaj   +1 more source

Position-effect variegation revisited: HUSHing up heterochromatin in human cells. [PDF]

open access: yes, 2016
Much of what we understand about heterochromatin formation in mammals has been extrapolated from forward genetic screens for modifiers of position-effect variegation (PEV) in the fruit fly Drosophila melanogaster.
Lehner, Paul J   +2 more
core   +1 more source

Exosomal Long Interspersed Nuclear Element‐1 Analytes Discriminate Histologic Subtypes, Sex, and Clinicopathological Characteristics of Patients with Non‐Small Cell Lung Cancer

open access: yesMedComm, Volume 6, Issue 11, November 2025.
Exosomal long interspersed nuclear element‐1 (LINE‐1) analytes exhibit distinct expression profiles across histologic subtypes of non‐small cell lung cancer (NSCLC) and demonstrate significant associations with clinicopathological characteristics. These findings underscore the potential of exosomal LINE‐1 mRNA as a minimally invasive biomarker for ...
Abeer A. I. Hassanin, Kenneth S. Ramos
wiley   +1 more source

Retroelement-Linked H3K4me1 Histone Tags Uncover Regulatory Evolution Trends of Gene Enhancers and Feature Quickly Evolving Molecular Processes in Human Physiology

open access: yesCells, 2019
Background: Retroelements (REs) are mobile genetic elements comprising ~40% of human DNA. They can reshape expression patterns of nearby genes by providing various regulatory sequences.
Daniil Nikitin   +8 more
doaj   +1 more source

Artificial Intelligence and the Evolving Landscape of Immunopeptidomics

open access: yesPROTEOMICS – Clinical Applications, Volume 19, Issue 6, November 2025.
ABSTRACT Background Immunopeptidomics is the large‐scale study of peptides presented by major histocompatibility complex (MHC) molecules and plays a central role in neoantigen discovery and cancer immunotherapy. However, the complexity of mass spectrometry data, the diversity of peptide sources, and variability in immune responses present major ...
Thanh Hoa Vo   +4 more
wiley   +1 more source

Distribution of a Ty3/gypsy-like retroelement on the A and B-chromosomes of Cestrum strigilatum Ruiz & Pav. and Cestrum intermedium Sendtn. (Solanaceae)

open access: yesGenetics and Molecular Biology, 2007
Retroelements are a diversified fraction of eukaryotic genomes, with the Ty1/copia and Ty3/gypsy groups being very common in a large number of plant genomes. We isolated an internal segment of the Ty3/gypsy retroelement of Cestrum strigilatum (Solanaceae)
Jéferson Nunes Fregonezi   +4 more
doaj   +1 more source

Endonuclease-containing Penelope retrotransposons in the bdelloid rotifer Adineta vaga exhibit unusual structural features and play a role in expansion of host gene families [PDF]

open access: yes, 2013
© The Author(s), 2013. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Mobile DNA 4 (2013): 19, doi:10.1186/1759-8753-4-19.Penelope-like elements (PLEs) are an enigmatic ...
Arkhipova, Irina R.   +2 more
core   +2 more sources

Saprotrophic Arachnopeziza Species as New Resources to Study the Obligate Biotrophic Lifestyle of Powdery Mildew Fungi

open access: yesMolecular Ecology Resources, Volume 25, Issue 8, November 2025.
ABSTRACT Obligate biotrophic plant pathogens like the powdery mildew fungi commit to a closely dependent relationship with their plant hosts and have lost the ability to grow and reproduce independently. Thus, at present, these organisms are not amenable to in vitro cultivation, which is a prerequisite for effective genetic modification and functional ...
Anne Loos   +7 more
wiley   +1 more source

HIV/AIDS Pandemia — a Problem Requiring Rethinking On the 30th Anniversary of the Discovery of Human Immunodeficiency Virus

open access: yesAktualʹnaâ Infektologiâ, 2014
Hazard of HIV/AIDS pandemia is greatly underestimated due to lack of understanding of its role in the processes that are not related to medicine. The principal difference between HIV/AIDS pandemia and the pandemic processes, against which the advances ...
M.V. Supotnitsky
doaj   +1 more source

The APOBEC3 Family of Retroelement Restriction Factors [PDF]

open access: yes, 2013
The ability to regulate and even target mutagenesis is an extremely valuable cellular asset. Enzyme-catalyzed DNA cytosine deamination is a molecular strategy employed by vertebrates to promote antibody diversity and defend against foreign nucleic acids.
Eric W, Refsland, Reuben S, Harris
openaire   +2 more sources

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