Results 111 to 120 of about 16,020 (245)

The Impact of Polyploid Giant Cancer Cells: The Root of Stress Resilience

open access: yesCancer Science, Volume 116, Issue 11, Page 2949-2958, November 2025.
Among the diverse characteristics of polyploid giant cancer cells (PGCCs) observed in various contexts, stress resilience is one of their key features, enabling survival and adaptation under harsh conditions. This review discusses the unique stress tolerance mechanisms of PGCCs and their implications for cancer progression, therapy resistance, and ...
Yuta Ogawa   +2 more
wiley   +1 more source

Targeted Variant Assessments of Human Endogenous Retroviral Regions in Whole Genome Sequencing Data Reveal Retroviral Variants Associated with Papillary Thyroid Cancer

open access: yesMicroorganisms
Papillary thyroid cancer (PTC) is one of the fastest-growing cancers worldwide, lacking established causal factors or validated early diagnostics. Human endogenous retroviruses (HERVs), comprising 8% of human genomes, have potential as PTC biomarkers due
Erik Stricker   +4 more
doaj   +1 more source

The 5'-end transitional CpGs between the CpG islands and retroelements are hypomethylated in association with loss of heterozygosity in gastric cancers [PDF]

open access: yes, 2006
BACKGROUND: A loss of heterozygosity (LOH) represents a unilateral chromosomal loss that reduces the dose of highly repetitive Alu, L1, and LTR retroelements.
Eun-Joo Seo   +6 more
core   +2 more sources

CDT retroelement [PDF]

open access: yesPlant Signaling & Behavior, 2008
The resurrection plant Craterostigma plantagineum can tolerate up to 96% loss of its water content and recover from such extreme dehydration within several hours. This property is not shared by callus which has a strict requirement for exogenous abscissic acid (ABA) to survive severe water loss.
openaire   +3 more sources

Supplementary Data from Endogenous Retroelement Activation by Epigenetic Therapy Reverses the Warburg Effect and Elicits Mitochondrial-Mediated Cancer Cell Death

open access: gold, 2023
Vicente Fresquet   +22 more
openalex   +1 more source

Identification and characterization of abundant repetitive sequences in Eragrostis tef cv. Enatite genome [PDF]

open access: yes, 2016
Multiple alignment of Ty1-copia RT paralog sequences identified in teff cv Enantite and Tsedey.
Bertolini, Edoardo   +3 more
core   +11 more sources

On the Origin and Evolutionary Relationships of the Reverse Transcriptases Associated With Type III CRISPR-Cas Systems

open access: yesFrontiers in Microbiology, 2018
Reverse transcriptases (RTs) closely related to those encoded by group II introns but lacking the intron RNA structure have been found associated with type III clustered regularly interspaced short palindromic repeats (CRISPR)-Cas systems, a prokaryotic ...
Nicolás Toro   +3 more
doaj   +1 more source

A pipeline of programs for collecting and analyzing group II intron retroelement sequences from GenBank [PDF]

open access: gold, 2013
Michael Abebe   +11 more
openalex   +1 more source

LINE-1 Retroelements Get ZAPped!

open access: yesPLOS Genetics, 2015
An acute viral infection begins a cascade of events in host organisms. Primed by an interferon response, host cells dramatically increase the expression of hundreds of interferon-stimulated genes (ISGs) that collectively attempt to block the virus at various stages of its intracellular cycle.
Richard N McLaughlin, Harmit S Malik
openaire   +4 more sources

Contribution of Mobile Group II Introns to Sinorhizobium meliloti Genome Evolution

open access: yesFrontiers in Microbiology, 2018
Mobile group II introns are ribozymes and retroelements that probably originate from bacteria. Sinorhizobium meliloti, the nitrogen-fixing endosymbiont of legumes of genus Medicago, harbors a large number of these retroelements.
Nicolás Toro   +4 more
doaj   +1 more source

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