Results 21 to 30 of about 50,812 (253)

Defending the genome from the enemy within:mechanisms of retrotransposon suppression in the mouse germline [PDF]

open access: yes, 2013
The viability of any species requires that the genome is kept stable as it is transmitted from generation to generation by the germ cells. One of the challenges to transgenerational genome stability is the potential mutagenic activity of transposable ...
Richard R. Meehan   +9 more
core   +1 more source

Small RNA pathways in mammalian oocytes. [PDF]

open access: yesFEBS Open Bio
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Svoboda P, Pasulka J.
europepmc   +2 more sources

Lost in translation : The biogenesis of non-LTR retrotransposon proteins [PDF]

open access: yes, 2013
This research was supported by UK Biotechnology and Biological Sciences Research Council (BBSRC) and the Wellcome Trust.“Young” APE-type non-LTR retrotransposons (non-LTRs) typically encode two open reading frames (ORFs 1 and 2).
Roulston, Claire   +11 more
core   +1 more source

Application of iPBS in high-throughput sequencing for the development of retrotransposon-based molecular markers

open access: yesCurrent Plant Biology, 2014
Retrotransposons are major components of higher plant genomes, and long terminal repeat (LTR) retrotransposons are especially predominant. Thus, numerous LTR retrotransposon families with high copy numbers exist in most plant genomes.
Yuki Monden   +2 more
doaj   +1 more source

An extracellular vesicle targeting ligand that binds to Arc proteins and facilitates Arc transport in vivo

open access: yeseLife, 2023
Communication between distant cells can be mediated by extracellular vesicles (EVs) that deliver proteins and RNAs to recipient cells. Little is known about how EVs are targeted to specific cell types.
Peter H Lee   +4 more
doaj   +1 more source

Comparative retrotransposon analysis of mutant and non-mutant rice varieties grown at different salt concentrations

open access: yesBiotechnology & Biotechnological Equipment, 2022
This study investigated the effects of retrotransposon movements on the regeneration of 15- and 30-day-old leaves and roots of four different rice varieties grown in tissue culture medium at different salt concentrations (0, 50, 100, and 200 mmol/L) by ...
Yunus Emre Arvas   +3 more
doaj   +1 more source

Retrotransposon-mediated evolutionary rewiring of a pathogen response orchestrates a resistance phenotype in an insect host

open access: yes, 2023
Ongoing host–pathogen interactions can trigger a coevolutionary arms race, while genetic diversity within the host can facilitate its adaptation to pathogens.
Shi Kang (722033)   +13 more
core   +1 more source

Short-term mutagenicity test by using IRAP molecular marker in rice grown under herbicide treatment

open access: yesBiotechnology & Biotechnological Equipment, 2018
Rice is an economically important plant as well as a model organism. The rice genome consists of 35% retrotransposons. Although most of the retrotransposons are inactivated through evolutionary processes, they can be activated under various biotic and ...
Sibel Yilmaz   +3 more
doaj   +1 more source

R-loop landscape in mature human sperm: Regulatory and evolutionary implications

open access: yesFrontiers in Genetics, 2023
R-loops are three-stranded nucleic acid structures consisting of an RNA:DNA hybrid and a displaced DNA strand. While R-loops pose a potential threat to genome integrity, they constitute 5% of the human genome.
Maurice Scheuren   +2 more
doaj   +1 more source

Comparative Analysis of Homologous Sequences of Saccharum officinarum and Saccharum spontaneum Reveals Independent Polyploidization Events

open access: yesFrontiers in Plant Science, 2018
Sugarcane (Saccharum spp. hybrids) is an economically important crop widely grown in tropical and subtropical regions for sugar and ethanol production.
Anupma Sharma   +11 more
doaj   +1 more source

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