Results 11 to 20 of about 50,812 (253)

Microarray analysis of LTR retrotransposon silencing identifies Hdac1 as a regulator of retrotransposon expression in mouse embryonic stem cells. [PDF]

PLoS Computational Biology, 2012
Retrotransposons are highly prevalent in mammalian genomes due to their ability to amplify in pluripotent cells or developing germ cells. Host mechanisms that silence retrotransposons in germ cells and pluripotent cells are important for limiting the ...
Judith Reichmann, James H Crichton, Monika J Madej, Mary Taggart, Philippe Gautier, Jose Luis Garcia-Perez, Richard R Meehan, Ian R Adams   +7 more
doaj   +2 more sources

Retrotransposon hypomethylation in melanoma and expression of a placenta-specific gene.

PLoS ONE, 2014
In the human placenta, DNA hypomethylation permits the expression of retrotransposon-derived genes that are normally silenced by methylation in somatic tissues.
Erin C Macaulay, Hester E Roberts, Xi Cheng, Aaron R Jeffs, Bruce C Baguley, Ian M Morison   +5 more
doaj   +2 more sources

LINE-1 Retrotransposons and Amyotrophic Lateral Sclerosis. [PDF]

Int J Mol Sci
Korošec T, Rogelj B, Župunski V.
europepmc   +3 more sources

The holozoan Capsaspora owczarzaki possesses a diverse complement of active transposable element families [PDF]

, 2014
Capsaspora owczarzaki, a protistan symbiont of the pulmonate snail Biomphalaria glabrata, is the centre of much interest in evolutionary biology due to its close relationship to Metazoa. The whole genome sequence of this protist has revealed new insights
Suga, Hiroshi, Carr, Martin
core   +4 more sources

Small Extracellular Vesicle Enrichment of a Retrotransposon-Derived Double-Stranded RNA: A Means to Avoid Autoinflammation?

Biomedicines, 2021
Small extracellular vesicles (SEVs) such as exosomes are released by multiple cell types. Originally believed to be a mechanism for selectively removing unwanted cellular components, SEVs have received increased attention in recent years for their ...
Marilou H. Barrios, Alexandra L. Garnham, Andrew D. Foers, Lesley Cheng-Sim, Seth L. Masters, Ken C. Pang   +5 more
doaj   +1 more source

The Imprinted Retrotransposon-Like Gene PEG11 (RTL1) Is Expressed as a Full-Length Protein in Skeletal Muscle from Callipyge Sheep [PDF]

, 2010
peer-reviewedMembers of the Ty3-Gypsy retrotransposon family are rare in mammalian genomes despite their abundance in invertebrates and some vertebrates.
Pearson, Roger, Colgrave, Michelle L., Bidwell, Christopher A., Vuocolo, Tony, Lynn, David J, Fleming-Waddell, Jolena N., Tellam, Ross L, Byrne, Keren, Cockett, Noelle E.   +8 more
core   +2 more sources

Low Sensitivity of Real Time PCRs Targeting Retrotransposon Sequences for the Detection of Schistosoma japonicum Complex DNA in Human Serum

Pathogens, 2021
While hybridization probe-based real-time PCR assays targeting highly repetitive multi-copy genome sequences for the diagnosis of S. mansoni complex or S.
Hagen Frickmann, Ulrike Loderstädt, Beatrice Nickel, Sven Poppert, Peter Odermatt, Somphou Sayasone, Marjan Van Esbroeck, Isabel Micalessi, Lieselotte Cnops, Poom Adisakwattana, Gérard Leboulle, Olfert Landt, Thorsten Thye, Egbert Tannich   +13 more
doaj   +1 more source

Comparative Repeat Profiling of Two Closely Related Conifers (Larix decidua and Larix kaempferi) Reveals High Genome Similarity With Only Few Fast-Evolving Satellite DNAs

Frontiers in Genetics, 2021
In eukaryotic genomes, cycles of repeat expansion and removal lead to large-scale genomic changes and propel organisms forward in evolution. However, in conifers, active repeat removal is thought to be limited, leading to expansions of their genomes ...
Tony Heitkam, Luise Schulte, Luise Schulte, Beatrice Weber, Susan Liedtke, Sarah Breitenbach, Anja Kögler, Kristin Morgenstern, Marie Brückner, Ute Tröber, Heino Wolf, Doris Krabel, Thomas Schmidt   +12 more
doaj   +1 more source

A molecular marker set combining a retrotransposon insertion and SSR polymorphisms is useful for assessing diversity in Vitis

OENO One, 2021
Molecular markers, based on DNA polymorphisms, are useful tools for identifying individuals, establishing phylogenetic relationships, managing collections of genetic material or assisting breeding.
Frederique Pelsy, Lucie Bevilacqua, Sophie Blanc, Didier Merdinoglu   +3 more
doaj   +1 more source

An Endogenous Retrovirus from Human Hookworm Encodes an Ancient Phlebovirus-Like Class II Envelope Fusion Protein

Proceedings, 2020
Within the parasitic nematode Ancylostoma ceylanicum, a ~20 million-year-old Bel/Pao LTR retrotransposon encodes an ancient viral class II envelope fusion protein termed Atlas Gc.
Monique Merchant, Carlos P. Mata, Yorgo Modis   +2 more
doaj   +1 more source