Results 71 to 80 of about 55,792 (268)

KRAB Zinc‐Finger Protein ZNF205 Promotes Hepatocellular Carcinoma via p53 Pathway Repression

Cancer Science, EarlyView.
ZNF205 functions as a critical oncogenic regulator in hepatocellular carcinoma (HCC), where it interacts with p53 and functionally suppresses its transcriptional activity by competitively inhibiting p53 binding to target gene promoters. This p53 inactivation mechanism critically contributes to tumor progression in HCC. ABSTRACT The tumor suppressor p53
Xiaofen Huang, Yingchuan Yang, Yuan Ma, Wei Hao, Jingzhuo Jin, Yue Ding, Yiming Zhang, Xiuyuan Zhang, Xinli Li, Qin Song, Jiaqi Liu, Bingxin Liu, Yuanjun Zhai, Chunling Zhao, Jin Wu, Chunyan Tian   +15 more
wiley   +1 more source

Genomic resource development for a diploid mint: Mentha longifolia [PDF]

, 2010
This research project aimed to develop genomic resources needed to enable construction of a genetic linkage map of the diploid mint species Mentha longifolia.
Hadadian, Zahra
core   +1 more source

FISH mapping and molecular organization of the major repetitive sequences of tomato [PDF]

, 2008
This paper presents a bird's-eye view of the major repeats and chromatin types of tomato. Using fluorescence in-situ hybridization (FISH) with Cot-1, Cot-10 and Cot-100 DNA as probes we mapped repetitive sequences of different complexity on pachytene ...
Chang, S.B., Datema, E., Jacobsen, E., Jong, J.H.S.G.M., de, Klein Lankhorst, R.M., Kuipers, A., Meznikova, M., Szinay, D., Vosman, B., Vugt, J., van, Yang, T.J.   +10 more
core   +2 more sources

Widespread horizontal transfer of retrotransposons [PDF]

Proceedings of the National Academy of Sciences, 2012
In higher organisms such as vertebrates, it is generally believed that lateral transfer of genetic information does not readily occur, with the exception of retroviral infection. However, horizontal transfer (HT) of protein coding repetitive elements is the simplest way to explain the patchy distribution of BovB, a long interspersed element (LINE ...
Walsh, A., Kortschak, R., Gardner, M., Bertozzi, T., Adelson, D.   +4 more
openaire   +3 more sources

Genome‐wide and gene‐specific DNA methylation across developmental stages in Pogonomyrmex californicus: A socially polymorphic ant

Insect Molecular Biology, EarlyView.
Comparison between developmental stages (larvae, pupae, worker) in Pogonomyrmex californicus revealed significant stage‐specific differences in Gene Body Methylated frequencies. Methylation sites were highly correlated between WGBS and ONT in P. californicus Genome‐wide methylation was low (~3%) and highly clustered within gene bodies (GBM), especially
Tania Chavarria‐Pizarro, Mohammed Errbii, Janina Rinke, Lukas Schrader, Jürgen Gadau   +4 more
wiley   +1 more source

The genome-defence gene Tex19.1 suppresses LINE-1 retrotransposons in the placenta and prevents intra-uterine growth retardation in mice [PDF]

, 2013
DNA methylation plays an important role in suppressing retrotransposon activity in mammalian genomes, yet there are stages of mammalian development where global hypomethylation puts the genome at risk of retrotransposition-mediated genetic instability ...
Aravin, Baillie, Barbosa-Morais, Barrett, Beck, Bersinger, Bode, Bourc'his, Celebi, Chapman, Chen, Coan, David Read, de Koning, Diana Best, Du, Dupressoir, Finkenzeller, Fowden, Frost, Gabory, Gautier, Goodier, Hackett, Hackett, Haig, Hajkova, Hajkova, Horst, Hudson, Hutnick, Ian R. Adams, Jackson-Grusby, James P. Reddington, Ji, Judith Reichmann, Karimi, Krackow, Kumaki, Lander, Leeb, Ma, Maksakova, Mao, Martin, Mi, Mietz, Ono, Popp, R Development Core Team, Razin, Reichmann, Reik, Reiss, Reynolds, Richard R. Meehan, Rossant, Rowe, Rupert Öllinger, Salas, Santos, Schütt, Sekita, Shaut, Simmons, Simmons, Simmons, Singer, Smyth, Solyom, Thorrez, Tsumura, Tunster, Walsh, Watanabe, Waterston, Yang, Yoder, Zheng, Öllinger, Öllinger   +80 more
core   +1 more source

Proteomic analysis of the zone of degeneration at the mitosis–meiosis transition stage in wild‐caught male catshark (Scyliorhinus canicula), correlated with an unusually high‐water temperature in the English Channel

Journal of Fish Biology, EarlyView.
Abstract In the context of current global change, variations in water temperature are one of the environmental conditions with serious consequences for marine life, including reproductive processes. In the small spotted catshark Scyliorhinus canicula, spermatogenesis occurs in spermatocysts composed of synchronously developing germ cells associated ...
Fabian Jeanne, Stanislas Pilet, Sean Heighton, Benoît Bernay, Pascal Sourdaine   +4 more
wiley   +1 more source

Assessment of genetic diversity in Iranian confectionary sunflower (Helianthus annuus L.) populations using retrotransposon based IRAP markers [PDF]

مجله بیوتکنولوژی کشاورزی, 2014
Genetic diversity is necessary for plant breeders to obtain new cultivars either with high yield, better quality, more adapted to abiotic stress or more resistant to pest and pathogens. Retrotransposons are current component of plant genomes. Ubiquitous,
Ashkan Basir Niya, Reza Darvish Zadeh, Babak Abdollahi, Alireza Nabi Pour   +3 more
doaj   +1 more source

Amplification and adaptation of centromeric repeats in polyploid switchgrass species. [PDF]

, 2018
Centromeres in most higher eukaryotes are composed of long arrays of satellite repeats from a single satellite repeat family. Why centromeres are dominated by a single satellite repeat and how the satellite repeats originate and evolve are among the most
Braz, Guilherme T, Casler, Michael D, Han, Yonghua, Jiang, Jiming, Schmutz, Jeremy, Yang, Xueming, Zeng, Zixian, Zhang, Pingdong, Zhang, Tao, Zhao, Hainan, Zhu, Bo   +10 more
core   +2 more sources

Restricting retrotransposons: a review [PDF]

Mobile DNA, 2016
Retrotransposons have generated about 40 % of the human genome. This review examines the strategies the cell has evolved to coexist with these genomic "parasites", focussing on the non-long terminal repeat retrotransposons of humans and mice. Some of the restriction factors for retrotransposition, including the APOBECs, MOV10, RNASEL, SAMHD1, TREX1 ...
openaire   +2 more sources