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Os Oncogenes e a Etiologia do Câncer
O artigo de opnião de Hector Seaunez Abreu, Chefe do Serviço de Genética do Instituto Nacional de Câncer (INCA), apresenta um breve resumo e atualização sobre a temática: Oncogenes e a Etiologia do Câncer.
Hector Seaunez Abreu
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Understanding the Enigmatic Dance of Immune-Mediated Viral Infections and Their Pathogenetic Mechanisms. [PDF]
This graphical representation illustrates the multifaceted nature of the immune response in viral infections, demonstrating both its protective and potentially harmful aspects. While a properly regulated immune reaction facilitates viral clearance and promotes general recovery, an overly robust or misdirected response—exemplified by Type III or Type IV
Karabulut MC, Oğuzoğlu TÇ.
europepmc +2 more sources
Envelope Determinants of Equine Lentiviral Vaccine Protection [PDF]
Lentiviral envelope (Env) antigenic variation and associated immune evasion present major obstacles to vaccine development. The concept that Env is a critical determinant for vaccine efficacy is well accepted, however defined correlates of protection ...
A Kumar+76 more
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Genetic diversity of Brazilian isolates of feline immunodeficiency virus [PDF]
We isolated Feline immunodeficiency virus (FIV) from three adult domestic cats, originating from two open shelters in Brazil. Viruses were isolated from PBMC following co-cultivation with the feline T-lymphoblastoid cell line MYA-1.
A Duarte+50 more
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Protease inhibitors targeting coronavirus and filovirus entry. [PDF]
In order to gain entry into cells, diverse viruses, including Ebola virus, SARS-coronavirus and the emerging MERS-coronavirus, depend on activation of their envelope glycoproteins by host cell proteases.
Agudelo, Juliet+10 more
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Feline Leukemia Virus in Cats: A Novel Rapid ELISA Assay for p27 Antigen Detection. [PDF]
Feline leukemia virus (FeLV) is an oncogenic immunosuppressive virus belonging to the Retroviridae family and one of the most common causes of a major infectious disorder in cats that can lead to potentially fatal associated diseases with a worse prognosis.
Ferrero I+4 more
europepmc +2 more sources
Ortervirales: A new viral order unifying five families of reverse-transcribing viruses [PDF]
Reverse-transcribing viruses, which synthesize a copy of genomic DNA from an RNA template, are widespread in animals, plants, algae and fungi (1, 2).
Blomberg, Jonas+29 more
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Influence of Immunogenetic Biomarkers in the Clinical Outcome of HTLV-1 Infected Persons
Human T-lymphotropic virus 1, a member of the Retroviridae family, causes a neglected, silent, persistent infection affecting circa 5 to 10 million people around the world, with biology, immune pathology, clinical diseases, epidemiology, and laboratory ...
Antonio Carlos Rosário Vallinoto+4 more
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HTLV-1 Tax-1 interacts with SNX27 to regulate cellular localization of the HTLV-1 receptor molecule, GLUT1 [PDF]
An estimated 10–20 million people worldwide are infected with human T cell leukemia virus type 1 (HTLV-1), with endemic areas of infection in Japan, Australia, the Caribbean, and Africa.
Al-Saleem, Jacob+6 more
core +3 more sources